Search Results - "Rimoldi, J.M."

Highly selective hydrolysis of kinins by recombinant prolylcarboxypeptidase by Chajkowski, S.M., Mallela, J., Watson, D.E., Wang, J., McCurdy, C.R., Rimoldi, J.M., Shariat-Madar, Z.

“…► The kinetic parameters of the kinin hydrolysis reaction by LC–MS. ► The correlation between K M and k cat values and the substrate structure. ► The IC 50 for…”
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Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis by Rabey, F M, Gadepalli, R S V S, Diano, S, Cheng, Q, Tabrizian, T, Gailani, D, Rimoldi, J M, Shariat-Madar, Z

“…Preclinical pharmacological characterization of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) was investigated. We synthesized and evaluated a…”
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The functional importance of the N-terminal region of human prolylcarboxypeptidase by Mallela, J., Perkins, R., Yang, J., Pedigo, S., Rimoldi, J.M., Shariat-Madar, Z.

“…The renin–angiotensin-system cascade pathway generates the vasopressor and prothrombotic hormones, angiotensin II (Ang II) and angiotensin III (Ang III) from…”
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Effects of the natural bromo-phenol, lanosol, on the expression and activities of various phase I and phase II enzymes from the digestive gland of the gumboot chiton, Cryptochiton stelleri by DeBusk, B.C., Chimote, S.S., Rimoldi, J.M., Schlenk, D.

“…Lanosol, found in the alga Odonthalia dentata, was administered to gumboot chitons ( Chryptochiton stelleri) by oral gavage at 0, 1, 2.5, 5, or 10 mg/kg for 4…”
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Modified Taxols, 9. Synthesis and Biological Evaluation of 7-Substituted Photoaffinity Analogues of Taxol by Rimoldi, John M, Kingston, David G. L, Chaudhary, Ashok G, Samaranayake, Gamini, Grover, Surinder, Hamel, Ernest

“…The 7-substituted taxol analogues 7, 19, 27, and 32 have been prepared as potential photoaffinity-labeled derivatives for studies of the nature of the binding…”
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An Improved Method for the Separation of Paclitaxel and Cephalomannine by Rimoldi, John M, Molinero, Anthony A, Chordia, Mahendra D, Gharpure, Milind M, Kingston, David G. I

“…Treatment of a mixture of paclitaxel and cephalomannine with bromine under mild conditions yields a readily separable mixture of paclitaxel and…”
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Modified traxols. 9. Synthesis and biological evaluation of 7-substituted photoaffinity analogues of taxol by Rimoldi, J.M, Kingston, D.G.I, Chaudhary, A.G, Samaranayake, G, Grover, S, Hamel, E

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