Search Results - "Rimm, IJ"

Tacrolimus (FK506) Increases Neuronal Expression of GAP-43 and Improves Functional Recovery after Spinal Cord Injury in Rats by Madsen, Joseph R., MacDonald, Paul, Irwin, Nina, Goldberg, David E., Yao, Gui-Lan, Meiri, Karina F., Rimm, Ilonna J., Stieg, Philip E., Benowitz, Larry I.

“…Tacrolimus (FK506), a widely used immunosuppressant drug, has neurite-promoting activity in cultured PC12 cells and peripheral neurons. The present study…”
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Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2) by Adler, H, Beland, J L, Del-Pan, N C, Kobzik, L, Brewer, J P, Martin, T R, Rimm, I J

“…Intranasal Herpes simplex virus type 1 (HSV-1) infection of mice caused pneumonia. Manifestations of the disease included: histological pneumonitis, pulmonary…”
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Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease by Antin, JH, Weinstein, HJ, Guinan, EC, McCarthy, P, Bierer, BE, Gilliland, DG, Parsons, SK, Ballen, KK, Rimm, IJ, Falzarano, G

“…Acute graft-versus-host disease (GVHD) that is resistant to therapy is a highly lethal complication of marrow transplantation. Inflammatory cytokines such as…”
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In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis by Adler, Heiko, Beland, Janice L, Del-Pan, Nadia C, Kobzik, Lester, Sobel, Raymond A, Rimm, Ilonna J

“…The importance of natural killer (NK) cells in the resistance to herpes simplex virus type 1 (HSV-1), a common infection of immunocompromised patients, is…”
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Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease by ANTIN, J. H, WEINSTEIN, H. J, BLOEDOW, D. C, ABATE, L, LEBSACK, M, BURAKOFF, S. J, FERRARA, J. L. M, GUINAN, E. C, MCCARTHY, P, BIERER, B. E, GILLILAND, D. G, PARSONS, S. K, BALLEN, K. K, RIMM, I. J, FALZARANO, G

“…Acute graft-versus-host disease (GVHD) that is resistant to therapy is a highly lethal complication of marrow transplantation. Inflammatory cytokines such as…”
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Bone marrow transplantation for therapy-related myelodysplasia : comparison with primary myelodysplasia by BALLEN, K. K, GILLILAND, D. G, GUINAN, E. C, HSIEH, C.-C, PARSONS, S. K, RIMM, I. J, FERRARA, J. L. M, BIERER, B. E, WEINSTEIN, H. J, ANTIN, J. H

“…Therapy-related myelodysplasia (MDS) is a fatal marrow disorder distinct from primary MDS. We examined the efficacy of bone marrow transplantation (BMT) as a…”
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B cell-deficient mice have increased susceptibility to HSV-1 encephalomyelitis and mortality by Beland, Janice L, Sobel, Raymond A, Adler, Heiko, Del-Pan, Nadia C, Rimm, Ilonna J

“…We studied the susceptibility of B cell-deficient mice to encephalomyelitis following intraperitoneal inoculation of HSV-1. B cell-deficient mice developed…”
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Recombinant CD40L Treatment Protects Allogeneic Murine Bone Marrow Transplant Recipients From Death Caused by Herpes Simplex Virus-1 Infection by Beland, Janice L., Adler, Heiko, Del-Pan, Nadia C., Kozlow, Wende, Sung, Janice, Fanslow, William, Rimm, Ilonna J.

“…Posttransplant infection associated with host immune deficiency is the major cause of nonrelapse mortality of human bone marrow transplant recipients. In a new…”
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Restriction of the TCR repertoire inhibits the development of memory T cells and prevents autoimmunity in lpr mice by Perkins, DL, Listman, JA, Marshak-Rothstein, A, Kozlow, W, Kelley, VR, Finn, PW, Rimm, IJ

“…The lpr mutation, a disruption of the fas gene, induces spontaneous autoimmunity characterized by high titers of autoantibodies, lymphadenopathy, autoreactive…”
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Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide by Wheeler, C, Strawderman, M, Ayash, L, Churchill, W H, Bierer, B E, Elias, A, Gilliland, D G, Antman, K, Guinan, E C, Eder, J P

“…We examined a consecutive series of 78 patients with non-Hodgkin's lymphoma treated on prospective protocols with high-dose cyclophosphamide, carmustine…”
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V(beta)8(+) T cells protect from demyelinating disease in a viral model of multiple sclerosis by Drescher, K M, Johnston, S L, Hogancamp, W, Nabozny, G H, David, C S, Rimm, I J, Wettstein, P J, Rodriguez, M

“…Previous studies illustrated the influence of T cell subsets on susceptibility or resistance to demyelination in the Theiler's murine encephalomyelitis virus…”
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T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice by Kuchroo, V K, Collins, M, al-Sabbagh, A, Sobel, R A, Whitters, M J, Zamvil, S S, Dorf, M E, Hafler, D A, Seidman, J G, Weiner, H L

“…Experimental allergic encephalomyelitis (EAE) is an autoimmune disease that can be induced in laboratory animals by immunization with the major myelin…”
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Bone marrow transplantation for the Wiskott-Aldrich syndrome. Long-term follow-up by Rimm, I J, Rappeport, J M

“…Wiskott-Aldrich Syndrome (WAS) is a sex-linked disease characterized by immunodeficiency and thrombocytopenia. Supportive treatment of this disease is…”
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Experimental autoimmune myasthenia gravis in B10.BV8S2 transgenic mice: preferential usage of TCRAV1 gene by lymphocytes responding to acetylcholine receptor by Kaul, R, Wu, B, Goluszko, E, Deng, C, Dedhia, V, Nabozny, GH, David, CS, Rimm, IJ, Shenoy, M, Haqqi, TM, Christadoss, P

“…Multiple TCRBV genes have been implicated in experimental autoimmune myasthenia gravis (EAMG) pathogenesis in susceptible H-2(b) strains of mice. We studied…”
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Superantigen-induced peripheral tolerance inhibits T cell responses to immunogenic peptides in TCR (beta-chain) transgenic mice by Perkins, DL, Wang, Y, Ho, SS, Wiens, GR, Seidman, JG, Rimm, IJ

“…TCR (beta-chain) transgenic mice were tolerized with the superantigen staphylococcal enterotoxin B (SEB). Three to 28 days after tolerization with SEB, flow…”
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Brain tumors after cranial irradiation for childhood acute lymphoblastic leukemia. A 13-year experience from the Dana-Farber Cancer Institute and the Children's Hospital by Rimm, I J, Li, F C, Tarbell, N J, Winston, K R, Sallan, S E

“…Brain tumors developed in two children after they had received cranial irradiation as central nervous system therapy for acute lymphoblastic leukemia. A review…”
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Immunodominance is altered in T cell receptor (beta-chain) transgenic mice without the generation of a hole in the repertoire by Perkins, DL, Wang, YS, Fruman, D, Seidman, JG, Rimm, IJ

“…Despite the tremendous plasticity of the TCR repertoire, T cells recognize a limited number of antigenic sites (frequently a single site, or immunodominant…”
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V beta 8.2 transgene expression interferes with development of experimental autoimmune thyroiditis in CBA k/q but not k/k mice by Lomo, L C, Motte, R W, Giraldo, A A, Nabozny, G H, David, C S, Rimm, I J, Kong, Y M

“…The thyroiditogenic T cell receptor (TCR) repertoire is not yet well defined in murine experimental autoimmune thyroiditis (EAT). Our recent work has shown…”
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Plasticity of the T Cell Receptor Repertoire in TCR β-Chain Transgenic Mice by Listman, James A., Rimm, Ilonna J., Wang, Yunsheng, Geller, Michelle C., Tang, J.C., Ho, Sam, Finn, Patricia W., Perkins, David L.

“…The potential αβ T cell receptor (TCR) repertoire in normal mice is extremely large and estimated by M. M. Davis and P. J. Bjorkman (Nature334, 395, 1988) to…”
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Differentiation of V beta 8.2+ CD4+ T cells induced by a superantigen: roles of antigen-presenting cells and cytokines by McKnight, A J, Shea, C M, Wiens, G R, Rimm, I J, Abbas, A K

“…The activation and subsequent differentiation of naive CD4+ T cells into functionally distinct effector cells is a vital step in the generation of an effective…”
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