Search Results - "Rimelen, Valérie"
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Identification and isolation from either adult human bone marrow or G-CSF−mobilized peripheral blood of CD34+ /CD133+ /CXCR4+ / Lin− CD45− cells, featuring morphological, molecular, and phenotypic characteristics of very small embryonic-like (VSEL) stem cells
Published in Experimental hematology (01-04-2011)“…Objective Recently, we demonstrated that normal human bone marrow (hBM)−derived CD34+ cells, released into the peripheral blood after granulocyte…”
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Developing Molecular Signatures for Chronic Lymphocytic Leukemia
Published in PloS one (05-06-2015)“…Chronic lymphocytic leukemia (CLL) is a clonal malignancy of mature B cells that displays a great clinical heterogeneity, with many patients having an indolent…”
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Long-term benefit of intracardiac delivery of autologous granulocyte–colony-stimulating factor-mobilized blood CD34+ cells containing cardiac progenitors on regional heart structure and function after myocardial infarct
Published in Cytotherapy (Oxford, England) (2009)“…Background aims Starting from experimental data proposing hematopoietic stem cells as candidates for cardiac repair, we postulated that human peripheral blood…”
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Molecular Mechanism of EGFR-TKI Resistance in EGFR -Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring
Published in Cancers (30-09-2021)“…Non-small cell lung cancer (NSCLC) is the most common cancer in the world. Activating epidermal growth factor receptor ( ) gene mutations are a positive…”
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Direct Targeting KRAS Mutation in Non-Small Cell Lung Cancer: Focus on Resistance
Published in Cancers (04-03-2022)“…KRAS is the most frequently mutated oncogene in non-small cell lung cancers (NSCLC), with a frequency of around 30%, and encoding a GTPAse that cycles between…”
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Good Profile of Efficacy/Tolerance of Bortezomib or Idelalisib in Waldenström Macroglobulinemia Associated with Acquired Von Willebrand Syndrome
Published in Journal of blood medicine (01-01-2020)“…Acquired von Willebrand syndrome (AVWS) in the setting of Waldenström macroglobulinemia (WM) is a challenging condition. No real standard of care is…”
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Acquired L718V/ TP53 co-mutation and discordant molecular pattern between plasmatic and cerebrospinal fluid in a bone and meningeal metastatic L858R+ non-small cell lung cancer: a case report
Published in Annals of translational medicine (15-03-2023)“…Osimertinib is approved in first line metastatic epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC). Acquired L718V mutation is…”
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A cytogenetic study of 397 consecutive acute myeloid leukemia cases identified three with a t(7;21) associated with 5q abnormalities and exhibiting similar clinical and biological features, suggesting a new, rare acute myeloid leukemia entity
Published in Cancer genetics (01-07-2012)“…The RUNX1 gene is implicated in numerous chromosomal translocations that occur in acute myeloid leukemia (AML) and result in chimeric genes. In this study, 397…”
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Good Profile of Efficacy/Tolerance of Bortezomib or Idelalisib in Waldenstrom Macroglobulinemia Associated with Acquired Von Willebrand Syndrome
Published in Journal of blood medicine (01-02-2020)“…Acquired von Willebrand syndrome (AVWS) in the setting of Waldenstrom macroglobulinemia (WM) is a challenging condition. No real standard of care is…”
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Acquired L718V/TP53 co-mutation and discordant molecular pattern between plasmatic and cerebrospinal fluid in a bone and meningeal metastatic L858R+ non-small cell lung cancer: a case report
Published in Annals of translational medicine (15-03-2023)“…BackgroundOsimertinib is approved in first line metastatic epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC). Acquired EGFR…”
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Bloodstream Progenitor-Cell Traffic In Primary Myelofibrosis Reveals Cell Subsets Showing Some Features Of Very-Small Embryonnic-Like Stem Cells (VSELs), Along With Endothelial (PEC), Mesenchymal (MPC) and Hematopoietic (HPC) Progenitor Cells
Published in Blood (15-11-2013)“…Primary myelofibrosis (PMF) is accompanied by an increase in the bloodstream circulation of some adult progenitor cells. Extramedullary hematopoiesis observed…”
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Developing Molecular Signatures for Chronic Lymphocytic Leukemia: e0128990
Published in PloS one (01-06-2015)“…Chronic lymphocytic leukemia (CLL) is a clonal malignancy of mature B cells that displays a great clinical heterogeneity, with many patients having an indolent…”
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Three Novel AML Cases Harboring the Semi-Cryptic t(7;21)(p22;q22) Translocation Expressing RUNX1-USP42 Fusion Transcripts Associated with Diploidy/Tetraploidy and/or 5q Alterations: a Probably Underestimated Combination
Published in Blood (19-11-2010)“…Abstract 2708 RUNX1 is implicated in numerous chromosomal abnormalities acquired in acute myeloid leukemia (AML). The most frequent one, the t(8;21) is…”
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