Search Results - "Rimbach, Katharina"

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling by Bretz, Niko P., Ridinger, Johannes, Rupp, Anne-Kathleen, Rimbach, Katharina, Keller, Sascha, Rupp, Christian, Marmé, Frederik, Umansky, Ludmila, Umansky, Viktor, Eigenbrod, Tatjana, Sammar, Marei, Altevogt, Peter

“…Tumor-derived exosomes have been shown to induce various immunomodulatory effects. However, the underlying signaling pathways are poorly understood. Here, we…”
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2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells by Rimbach, Katharina, Kaiser, Steffen, Helm, Mark, Dalpke, Alexander H., Eigenbrod, Tatjana

“…Microbial RNA is an important stimulator of innate immune responses. Differences in posttranscriptional RNA modification profiles enable the immune system to…”
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A modified dinucleotide motif specifies tRNA recognition by TLR7 by Kaiser, Steffen, Rimbach, Katharina, Eigenbrod, Tatjana, Dalpke, Alexander H, Helm, Mark

“…RNA can function as a pathogen-associated molecular pattern (PAMP) whose recognition by the innate immune system alerts the body to an impending microbial…”
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Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity by Gehrig, Stefanie, Eberle, Mariel-Esther, Botschen, Flavia, Rimbach, Katharina, Eberle, Florian, Eigenbrod, Tatjana, Kaiser, Steffen, Holmes, Walter M, Erdmann, Volker A, Sprinzl, Mathias, Bec, Guillaume, Keith, Gérard, Dalpke, Alexander H, Helm, Mark

“…Naturally occurring nucleotide modifications within RNA have been proposed to be structural determinants for innate immune recognition. We tested this…”
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Recognition of Specified RNA Modifications by the Innate Immune System by Eigenbrod, Tatjana, Keller, Patrick, Kaiser, Steffen, Rimbach, Katharina, Dalpke, Alexander H, Helm, Mark

“…Microbial nucleic acids have been described as important activators of human innate immune responses by triggering so-called pattern recognition receptors…”
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