Search Results - "Rima Manafi Shabestari"
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Inhibition of Skp2 enhances doxorubicin‐induced cell death in B cell precursor acute lymphoblastic leukemia
Published in Cell biology international (01-06-2022)“…S‐phase kinase‐associated protein 2 (Skp2) is a well‐defined component of the Skp2‐Culin1‐F‐box (SCF) E3 ubiquitin ligase complex, which is involved in cell…”
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Use of antioxidant nanoparticles to reduce oxidative stress in blood storage
Published in Biotechnology and applied biochemistry (01-08-2022)“…Oxidative damage by free radicals has a negative effect on blood quality during storage. Antioxidant nanoparticles can prevent oxidative stress. We use…”
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Indole-3-carbinol induces apoptosis of chronic myelogenous leukemia cells through suppression of STAT5 and Akt signaling pathways
Published in Tumor biology (01-06-2017)“…Signal transducer and activator of transcription 5 and Akt pathways, implicated in signaling transduction downstream of BCR–ABL, play critical roles in the…”
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Cyclic AMP-Induced p53 Destabilization is Independent of CREB in Pre-B Acute Lymphoblastic Leukemia Cells
Published in International journal of molecular and cellular medicine (2016)“…Elevated cAMP levels in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells attenuate the doxorubicin-induced p53 accumulation and protect cells…”
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Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells
Published in Journal of cellular biochemistry (01-08-2019)“…Despite an old history behind the identification of the leading role of c‐Myc in leukemogenesis, the road to constructing a therapeutic perspective for this…”
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CREB knockdown inhibits growth and induces apoptosis in human pre-B acute lymphoblastic leukemia cells through inhibition of prosurvival signals
Published in Biomedicine & pharmacotherapy (01-03-2017)“…Abstract A majority of acute lymphoblastic leukemia patients overexpress CREB in the bone marrow. However, the functional significance of this up-regulation…”
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A straightforward microfluidic-based approach toward optimizing transduction efficiency of HIV-1-derived lentiviral vectors in BCP-ALL cells
Published in Biotechnology reports (Amsterdam, Netherlands) (01-06-2023)“…•Lentiviral vectors have a limited half-life, and in order to reach the target, the distance between the target cell and the vector should be…”
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Overexpression of long non-coding RNA ANRIL in B-acute lymphoblastic leukemia
Published in Iranian journal of pediatric hematology and oncology (29-06-2021)“…Background: Dysregulation of LncRNA antisense non-coding RNA in the INK4 locus (ANRIL) expression is implicated in pathogenesis and disease progression of a…”
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Overexpression of MiR-138 Inhibits Cell Growth and Induces Caspase-mediated Apoptosis in Acute Promyelocytic Leukemia Cell Line
Published in International journal of molecular and cellular medicine (01-01-2018)“…Dysregulated expression of miRNAs can play a vital role in pathogenesis of leukemia. The shortened telomere length, and elevated telomerase activity in acute…”
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Synergistic apoptotic effect of Mcl-1 inhibition and doxorubicin on B-cell precursor acute lymphoblastic leukemia cells
Published in Molecular biology reports (01-03-2022)“…Background Myeloid cell leukemia-1 (MCL-1) is a component of the Bcl-2 anti-apoptotic family that plays a key role in cell proliferation and differentiation…”
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TLR3 stimulation improves the migratory potency of adipose-derived mesenchymal stem cells through the stress response pathway in the melanoma mouse model
Published in Molecular biology reports (01-03-2023)“…Background Mesenchymal stem cells (MSCs) are utilized as a carrier of anti-tumor agents in targeted anti-cancer therapy. Despite the improvements in this area,…”
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12
The Molecular Structure and Case Fatality Rate of COVID-19
Published in Translational research in urology (01-08-2020)“…A new coronavirus recognized as 2019 novel coronavirus (COVID-19) is the etiological cause in charge of the 2019-2020 viral pneumonia worldwide outbreak. The…”
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