Search Results - "Riley, Robert"
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1
Complex, Higher-Risk, and Indicated PCI (CHIP) Fellowship: Putting Training Into Practice
Published in Journal of the American College of Cardiology (03-03-2020)Get full text
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2
Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Artery Disease
Published in Journal of the American College of Cardiology (01-12-2020)“…Coronary calcification hinders stent delivery and expansion and is associated with adverse outcomes. Intravascular lithotripsy (IVL) delivers acoustic pressure…”
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3
Reply to: Letter to the Editor
Published in Catheterization and cardiovascular interventions (01-11-2020)Get full text
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4
The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development
Published in Archives of toxicology (01-08-2020)“…Early identification of toxicity associated with new chemical entities (NCEs) is critical in preventing late-stage drug development attrition. Liver injury…”
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Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery
Published in Expert opinion on drug discovery (02-12-2019)“…: Prediction of human absorption, distribution, metabolism, and excretion (ADME) properties, therapeutic dose and exposure has become an integral part of…”
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A new paradigm for navigating compound property related drug attrition
Published in Drug discovery today (01-01-2016)“…•We propose properties related to drug–transporter interactions and drug attrition.•This space consists of compounds with PSA>75 and clogP<3.•This space…”
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7
Maxillomandibular Advancement for Treatment of Obstructive Sleep Apnea: A Meta-analysis
Published in JAMA otolaryngology-- head & neck surgery (01-01-2016)“…Maxillomandibular advancement (MMA) is an invasive yet effective surgical option for obstructive sleep apnea (OSA) that achieves enlargement of the upper…”
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Intravascular Imaging During Percutaneous Coronary Intervention: JACC State-of-the-Art Review
Published in Journal of the American College of Cardiology (14-02-2023)“…Coronary angiography has historically served as the gold standard for diagnosis of coronary artery disease and guidance of percutaneous coronary intervention…”
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Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists
Published in Nature genetics (01-04-2015)“…Francis Martin and colleagues report genome sequences for 18 species of mycorrhizal fungi and a phylogenomic analysis including 32 other fungal genomes. The…”
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Global chronic total occlusion crossing algorithm: JACC state-of-the-Art review
Published in Journal of the American College of Cardiology (24-08-2021)“…© 2021 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC-BY-NC-ND…”
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Intravascular Lithotripsy for Treatment of Calcified Coronary Lesions: Patient-Level Pooled Analysis of the Disrupt CAD Studies
Published in JACC. Cardiovascular interventions (28-06-2021)“…The aim of this pooled analysis was to assess the cumulative safety and effectiveness of coronary intravascular lithotripsy (IVL). The clinical outcomes of IVL…”
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Novel Transcatheter Mitral Valve Prosthesis for Patients With Severe Mitral Annular Calcification
Published in Journal of the American College of Cardiology (17-09-2019)“…Treatment of mitral regurgitation (MR) in the setting of severe mitral annular calcification (MAC) is challenging due to the high risk for fatal…”
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13
Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2014)“…Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most wood-decaying species, as well as pathogens and mutualistic symbionts…”
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14
Polarimetric Interferometric SAR Change Detection Discrimination
Published in IEEE transactions on geoscience and remote sensing (01-06-2019)“…A coherent change detection (CCD) image, computed from a geometrically matched, temporally separated pair of complex-valued synthetic aperture radar (SAR)…”
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A comparative genomics study of 23 Aspergillus species from section Flavi
Published in Nature communications (27-02-2020)“…Section Flavi encompasses both harmful and beneficial Aspergillus species, such as Aspergillus oryzae , used in food fermentation and enzyme production, and…”
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The first cut is the deepest (and perhaps the most opportune)
Published in Catheterization and cardiovascular interventions (01-09-2021)“…Key Points The rate of redo‐coronary artery bypass graft (CABG) nearly doubled from 5.33% in 2004 to 10.3% in 2015 and was associated with significantly higher…”
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The HEART Pathway randomized trial: identifying emergency department patients with acute chest pain for early discharge
Published in Circulation Cardiovascular quality and outcomes (01-03-2015)“…The HEART Pathway is a decision aid designed to identify emergency department patients with acute chest pain for early discharge. No randomized trials have…”
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Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization
Published in Science (American Association for the Advancement of Science) (22-07-2016)“…Mitochondria are inherited maternally in most animals, but the mechanisms of selective paternal mitochondrial elimination (PME) are unknown. While examining…”
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Comparative genomics of biotechnologically important yeasts
Published in Proceedings of the National Academy of Sciences - PNAS (30-08-2016)“…Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here, we report the comparative genome analysis of 29 taxonomically and…”
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Diazaphospholene‐Catalyzed Radical Reactions from Aryl Halides
Published in Angewandte Chemie International Edition (25-07-2022)“…Diazaphospholenes are widely used as hydride transfer catalysts, however their use in radical reactions is a recently emerging area. Here, we show prior…”
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