Search Results - "Riley, Margaret"
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The critical period: neurochemical and synaptic mechanisms shared by the visual cortex and the brain stem respiratory system
Published in Proceedings of the Royal Society. B, Biological sciences (08-09-2021)“…The landmark studies of Wiesel and Hubel in the 1960's initiated a surge of investigations into the critical period of visual cortical development, when…”
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Functional Gold Nanoparticles as Potent Antimicrobial Agents against Multi-Drug-Resistant Bacteria
Published in ACS nano (28-10-2014)“…We present the use of functionalized gold nanoparticles (AuNPs) to combat multi-drug-resistant pathogenic bacteria. Tuning of the functional groups on the…”
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Identifying more targeted antimicrobials active against selected bacterial phytopathogens
Published in Journal of applied microbiology (01-06-2022)“…Aims Phytopathogens are a global threat to the world’s food supply. The use of broad‐spectrum bactericides and antibiotics to limit or eliminate bacterial…”
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Uncovering a critical period of synaptic imbalance during postnatal development of the rat visual cortex: role of brain‐derived neurotrophic factor
Published in The Journal of physiology (01-09-2018)“…Key points With daily electrophysiological recordings and neurochemical analysis, we uncovered a transient period of synaptic imbalance between enhanced…”
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Nuclear Respiratory Factor 1 Regulates All Ten Nuclear-encoded Subunits of Cytochrome c Oxidase in Neurons
Published in The Journal of biological chemistry (08-02-2008)“…Cytochrome c oxidase (COX) is one of only four bigenomic proteins in mammalian cells, having ten subunits encoded in the nuclear genome and three in the…”
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Mechanisms underlying a critical period of respiratory development in the rat
Published in Respiratory physiology & neurobiology (01-06-2019)“…•Basic mechanisms underlying a critical period of respiratory development are discussed.•Abrupt neurochemical, ventilatory and electrophysiological changes…”
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Whole-genome sequencing in outbreak analysis
Published in Clinical microbiology reviews (01-07-2015)“…In addition to the ever-present concern of medical professionals about epidemics of infectious diseases, the relative ease of access and low cost of obtaining,…”
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Regulation of Na+/K+-ATPase by neuron-specific transcription factor Sp4: implication in the tight coupling of energy production, neuronal activity and energy consumption in neurons
Published in The European journal of neuroscience (01-02-2014)“…A major source of energy demand in neurons is the Na+/K+‐ATPase pump that restores the ionic gradient across the plasma membrane subsequent to depolarizing…”
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Peripheral–central chemoreceptor interaction and the significance of a critical period in the development of respiratory control
Published in Respiratory physiology & neurobiology (01-01-2013)“…Abstract Respiratory control entails coordinated activities of peripheral chemoreceptors (mainly the carotid bodies) and central chemosensors within the brain…”
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Pituitary adenylate cyclase-activating polypeptide: Postnatal development in multiple brain stem respiratory-related nuclei in the rat
Published in Respiratory physiology & neurobiology (01-01-2019)“…•Pituitary adenylate cyclase-activating polypeptide is known to control breathing.•A critical period of respiratory development exists in rats at postnatal…”
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Postnatal development of brain-derived neurotrophic factor (BDNF) and tyrosine protein kinase B (TrkB) receptor immunoreactivity in multiple brain stem respiratory-related nuclei of the rat
Published in Journal of comparative neurology (1911) (01-01-2013)“…Previously, we found a transient imbalance between suppressed excitation and enhanced inhibition in the respiratory network of the rat around postnatal days…”
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Energy metabolism of the visual system
Published in Eye and brain (01-01-2010)“…The visual system is one of the most energetically demanding systems in the brain. The currency of energy is ATP, which is generated most efficiently from…”
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Bigenomic regulation of cytochrome c oxidase in neurons and the tight coupling between neuronal activity and energy metabolism
Published in Advances in experimental medicine and biology (01-01-2012)“…Cytochrome c oxidase is the terminal enzyme of the mitochondrial electron transport chain, without which oxidative metabolism cannot be carried to completion…”
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Neuron‐specific specificity protein 4 bigenomically regulates the transcription of all mitochondria‐ and nucleus‐encoded cytochrome c oxidase subunit genes in neurons
Published in Journal of neurochemistry (01-11-2013)“…Neurons are highly dependent on oxidative metabolism for their energy supply, and cytochrome c oxidase (COX) is a key energy‐generating enzyme in the…”
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Chronic intermittent hypoxia alters the dendritic mitochondrial structure and activity in the pre‐Bötzinger complex of rats
Published in The FASEB journal (01-11-2020)“…Mitochondrial bioenergetics is dynamically coupled with neuronal activities, which are altered by hypoxia‐induced respiratory neuroplasticity. Here we report…”
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Nuclear respiratory factor 1 co-regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy metabolism in neurons
Published in Journal of neurochemistry (01-03-2009)“…Neuronal activity, especially of the excitatory glutamatergic type, is highly dependent on energy from the oxidative pathway. We hypothesized that the coupling…”
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Postnatal development of glycine receptor subunits α1, α2, α3, and β immunoreactivity in multiple brain stem respiratory-related nuclear groups of the rat
Published in Brain research (13-11-2013)“…The respiratory system is immature at birth and significant development occurs postnatally. A critical period of respiratory development occurs in rats around…”
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Competitive interactions in Escherichia coli populations: the role of bacteriocins
Published in The ISME Journal (01-01-2011)“…Explaining the coexistence of competing species is a major challenge in community ecology. In bacterial systems, competition is often driven by the production…”
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Postnatal changes in tryptophan hydroxylase and serotonin transporter immunoreactivity in multiple brainstem nuclei of the rat: Implications for a sensitive period
Published in Journal of comparative neurology (1911) (01-04-2010)“…Previously, we found that the brainstem neuronal network in normal rats undergoes abrupt neurochemical, metabolic, and physiological changes around postnatal…”
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Reduced levels of brain-derived neurotrophic factor contribute to synaptic imbalance during the critical period of respiratory development in rats
Published in The European journal of neuroscience (01-07-2014)“…Previously, our electrophysiological studies revealed a transient imbalance between suppressed excitation and enhanced inhibition in hypoglossal motoneurons of…”
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