Search Results - "Riley, C M"

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity by Müller, Lutz, Mauthe, Robert J., Riley, Christopher M., Andino, Marta M., Antonis, David De, Beels, Chris, DeGeorge, Joseph, De Knaep, Alfons G.M., Ellison, Dean, Fagerland, Jane A., Frank, Rebecca, Fritschel, Betsy, Galloway, Sheila, Harpur, Ernie, Humfrey, Charles D.N., Jacks, Alexander S., Jagota, Nirdosh, Mackinnon, John, Mohan, Ganapathy, Ness, Daniel K., O’Donovan, Michael R., Smith, Mark D., Vudathala, Gopi, Yotti, Larry

“…The synthesis of pharmaceutical products frequently involves the use of reactive reagents and the formation of intermediates and by-products. Low levels of…”
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Ethnobotany/ethnopharmacology and mass bioprospecting: Issues on intellectual property and benefit-sharing by Soejarto, D.D., Fong, H.H.S., Tan, G.T., Zhang, H.J., Ma, C.Y., Franzblau, S.G., Gyllenhaal, C., Riley, M.C., Kadushin, M.R., Pezzuto, J.M., Xuan, L.T., Hiep, N.T., Hung, N.V., Vu, B.M., Loc, P.K., Dac, L.X., Binh, L.T., Chien, N.Q., Hai, N.V., Bich, T.Q., Cuong, N.M., Southavong, B., Sydara, K., Bouamanivong, S., Ly, H.M., Thuy, Tran Van, Rose, W.C., Dietzman, G.R.

“…Ethnobotany/ethnopharmacology has contributed to the discovery of many important plant-derived drugs. Field explorations to seek and document…”
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Sizes and Shapes of 10‐Ma Distal Fall Pyroclasts in the Ogallala Group, Nebraska by Rose, W. I., Riley, C. M., Dartevelle, S.

“…Size distributions of distal ashfall particles from correlated 10‐Ma layers in Nebraska, measured using laser diffraction methods, are lognormal with mode…”
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Observations of Volcanic Clouds in Their First Few Days of Atmospheric Residence: The 1992 Eruptions of Crater Peak, Mount Spurr Volcano, Alaska by Rose, William I., Bluth, Gregg J. S., Schneider, David J., Ernst, Gerald G. J., Riley, Colleen M., Henderson, Lydia J., McGimsey, Robert G.

“…Satellite SO2and ash measurements of Mount Spurr’s three 1992 volcanic clouds are compared with ground‐based observations to develop an understanding of the…”
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A Simulation Model to Analyze Current Split Distribution of Multiple Temporary Protective Grounds (TPGs) by Poda, Anil B., Riley, C. M., Perkel, Josh, Hampton, R.N., Patel, Shashi, Lancaster, Thomas

“…The main purpose of Temporary Protective Grounds (TPGs) is to maximize personnel safety while working on any de-energized power equipment. ASTM F855 specified…”
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Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD by Strollo, Hilary C, Nouraie, Seyed M, Hoth, Karin F, Riley, Craig M, Karoleski, Chad, Zhang, Yingze, Hanania, Nicola A, Bowler, Russell P, Bon, Jessica, Sciurba, Frank C

“…Depression is a prevalent comorbidity of chronic obstructive pulmonary disease (COPD) that, along with COPD, has been associated with inflammation. An…”
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In vitro metabolism studies of the prodrug, 2′,3′,5′-triacetyl-6-azauridine, utilizing an automated analytical system by Zhou, J., Riley, C.M., Schowen, R.L.

“…The purpose was to study in vitro metabolism of 2′,3′,5′-triacetyl-6-azauridine ( 1) by porcine liver esterase (PLE) and in human plasma using an automated…”
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Quantitative shape measurements of distal volcanic ash by Riley, Colleen M., Rose, William I., Bluth, Gregg J. S.

“…Large‐scale volcanic eruptions produce fine ash (<200 μm) which has a long atmospheric residence time (1 hour or more) and can be transported great distances…”
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An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development by Soejarto, D D, Gyllenhaal, C, Kadushin, M R, Southavong, B, Sydara, K, Bouamanivong, S, Xaiveu, M, Zhang, H-J, Franzblau, S G, Tan, Ghee T, Pezzuto, J M, Riley, M C, Elkington, B G, Waller, D P

“…An ethnobotany-based approach in the selection of raw plant materials to study was implemented. To acquire raw plant materials using ethnobotanical field…”
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Dermal microdialysis sampling in vivo by AULT, J. M, RILEY, C. M, MELTZER, N. M, LUNTE, C. E

“…Microdialysis sampling of the dermis in vivo was accomplished using a linear microdialysis probe. In contrast to previous studies using a commercial…”
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A quantitative circular dichroic investigation of the binding of the enantiomers of ibuprofen and naproxen to human serum albumin by Cheruvallath, V.K, Riley, C.M, Narayanan, S.R, Lindenbaum, S, Perrin, J.H

“…The binding constants for racemic, R and S naproxen and ibuprofen to human serum albumin have been determined by a circular dichroic technique. The ibuprofens…”
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Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis by Gyllenhaal, C, Kadushin, M R, Southavong, B, Sydara, K, Bouamanivong, S, Xaiveu, M, Xuan, L T, Hiep, N T, Hung, N V, Loc, P K, Dac, L X, Bich, T Q, Cuong, N M, Ly, H M, Zhang, H J, Franzblau, S G, Xie, H, Riley, M C, Elkington, B G, Nguyen, H T, Waller, D P, Ma, C Y, Tamez, P, Tan, G T, Pezzuto, J M, Soejarto, D D

“…Whether natural product drug discovery programs should rely on wild plants collected "randomly" from the natural environment, or whether they should also…”
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The effects of sucrose on stability of human brain natriuretic peptide [hBNP (1-32)] and human parathyroid hormone [hPTH (1-34)] by Kamberi, M., Kim, Y.J., Jun, B., Riley, C.M.

“…:  Although the effect of sucrose on the physical stability of proteins has been well documented, its impact on their chemical stability is largely unknown…”
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Ossification of the external ear : a case report and review of the literature by MANNI, Johannes J, BERENOS-RILEY, Lysandra C. M

“…A rare case of idiopathic bilateral ossification of the auricular cartilage and cartilage of the external ear canal is reported. The hardening and thickening…”
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Automated analytical systems for drug development studies. V. A system for enzyme kinetic studies by Zhou, J., Shearer, E.C., Hong, J., Riley, C.M., Schowen, R.L.

“…Two similar automated analytical systems using liquid chromatography (LC) and microdialysis as an on-line sampling technique were applied to studies of enzyme…”
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The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism by Kurz, Linda C, Moix, Luke, Riley, Marian C, Frieden, Carl

“…We have previously shown that purine riboside, when bound to adenosine deaminase, forms a complex in which C-6 of the purine is tetrahedral [Kurz, L. C., &…”
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Oxygen radicals and reactive oxygen species in reproduction by Riley, J C, Behrman, H R

“…Free radicals and reactive oxygen species play a number of significant and diverse roles in reproductive biology. In common with other biological systems,…”
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The polysomnographic effects of clonidine on sleep disorders in posttraumatic stress disorder: a pilot study with Cambodian patients by Kinzie, J D, Sack, R L, Riley, C M

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Characterization of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy by Riley, C M, Ross, D L, Vander Velde, D, Takusagawa, F

“…The complexation of the fluoroquinolone antimicrobials is important because it has been implicated in reduced oral bioavailability and reduced antimicrobial…”
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Hydrolysis of the prodrug, 2',3',5'-triacetyl-6-azauridine by RILEY, C. M, MUMMERT, M. A, ZHOU, J, SCHOWEN, R. L, VANDER VELDE, D. G, MORTON, M. D, SLAVIK, M

“…The purposes were to study the kinetics of hydrolysis of 2',3',5'-triacetyl-6-azauridine (1) in aqueous solution (mu = 0.5) and to identify the main…”
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