Search Results - "Rilak Simović, Ana"

Chemistry and reactivity of ruthenium(II) complexes: DNA/protein binding mode and anticancer activity are related to the complex structure by Rilak Simović, Ana, Masnikosa, Romana, Bratsos, Ioannis, Alessio, Enzo

“…[Display omitted] •This review focusses on the structural features of Ru(II) complexes.•The review provides an overview of the anticancer activity of Ru(II)…”
Get full text

New ruthenium(II) complexes with quinone diimine and substituted bipyridine as inert ligands: synthesis, characterization, mechanism of action, DNA/HSA binding affinity and cytotoxic activity by Međedović, Milica, Rilak Simović, Ana, Ćoćić, Dušan, Senft, Laura, Matić, Sanja, Todorović, Danijela, Popović, Suzana, Baskić, Dejan, Petrović, Biljana

“…This paper presents the synthesis and structural characterization of a series of new ruthenium(II) complexes 1-7, with the general formula -[RuL ( - )Cl]Cl,…”
Get more information

Antitumor Activity of Ruthenium(II) Terpyridine Complexes towards Colon Cancer Cells In Vitro and In Vivo by Savic, Maja, Arsenijevic, Aleksandar, Milovanovic, Jelena, Stojanovic, Bojana, Stankovic, Vesna, Rilak Simovic, Ana, Lazic, Dejan, Arsenijevic, Nebojsa, Milovanovic, Marija

“…Ruthenium complexes have attracted considerable interest as potential antitumor agents. Therefore, antitumor activity and systemic toxicity of ruthenium(II)…”
Get full text

Anti-adhesive action of novel ruthenium(II) chlorophenyl terpyridine complexes with a high affinity for double-stranded DNA: in vitro and in silico by Masnikosa, Romana, Milutinović, Milan M., Crnolatac, Ivo, Tot, Aleksandar, Veličković, Suzana, Bojić-Trbojević, Žanka, Rilak-Simović, Ana

“…Interactions of three Ru(II) chlorophenyl terpyridine complexes: [Ru(Cl-Ph-tpy)(en)Cl]Cl (1), [Ru(Cl-Ph-tpy)(dach)Cl]Cl (2) and [Ru(Cl-Ph-tpy)(bpy)Cl]Cl (3)…”
Get full text

A new bis-pyrazolylpyridine ruthenium(III) complex as a potential anticancer drug: in vitro and in vivo activity in murine colon cancer by Lazić, Dejan, Scheurer, Andreas, Ćoćić, Dušan, Milovanović, Jelena, Arsenijević, Aleksandar, Stojanović, Bojana, Arsenijević, Nebojša, Milovanović, Marija, Rilak Simović, Ana

“…We synthesized and characterized the ruthenium(iii) pincer-type complex [RuCl3(H2Lt-Bu] (H2Lt-Bu = 2,6-bis(5-tert-butyl-1H-pyrazol-3-yl)pyridine, 1) by…”
Get more information

New gold pincer-type complexes: synthesis, characterization, DNA binding studies and cytotoxicity by Radisavljević, SneŽana, Bratsos, Ioannis, Scheurer, Andreas, Korzekwa, Jana, Masnikosa, Romana, Tot, Aleksandar, Gligorijević, Nevenka, Radulović, Siniša, Rilak Simović, Ana

“…With the aim of assessing whether Au(iii) compounds with pincer type ligands might be utilized as potential antitumor agents, three new monofunctional Au(iii)…”
Get more information

Newly Synthesized Heteronuclear Ruthenium(II)/Ferrocene Complexes Suppress the Growth of Mammary Carcinoma in 4T1-Treated BALB/c Mice by Promoting Activation of Antitumor Immunity by Milutinović, Milan M, Čanović, Petar P, Stevanović, Dragana, Masnikosa, Romana, Vraneš, Milan, Tot, Aleksandar, Zarić, Milan M, Simović Marković, Bojana, Misirkić Marjanović, Maja, Vučićević, Ljubica, Savić, Maja, Jakovljević, Vladimir, Trajković, Vladimir, Volarević, Vladislav, Kanjevac, Tatjana, Rilak Simović, Ana

“…The two new heterometallic Ru­(II)-tpy/ferrocene complexes [Ru­(tpy)­Cl2(mtefc)] (1) and [Ru­(tpy)­Cl2(mtpfc)] (2) (where tpy = 2,2′:6′,2′′-terpyridine, mtefc…”
Get full text

New gold pincer-type complexes induce caspase-dependent apoptosis in human cancer cells in vitro by Zaric, Milan, Canovic, Petar, Stanojevic-Pirkovic, Marijana, Knezevic, Sanja, Zivkovic-Zaric, Radica, Popovska-Joviĉic, Biljana, Hamzagic, Nedim, Simovic-Markovic, Bojana, Markovic, Nenad, Rilak-Simovic, Ana

“…Background/Aim. The use of cisplatin as a chemotherapeutic opened the door to the new metal-based drug research. New complexes containing metals such as…”
Get full text

Synthesis, characterization, biomolecular interactions, molecular docking, and in vitro and in vivo anticancer activities of novel ruthenium(III) Schiff base complexes by Međedović, Milica, Mijatović, Aleksandar, Baošić, Rada, Lazić, Dejan, Milanović, Žiko, Marković, Zoran, Milovanović, Jelena, Arsenijević, Dragana, Stojanović, Bojana, Arsenijević, Miloš, Milovanović, Marija, Petrović, Biljana, Simović, Ana Rilak

“…In order to discover new anticancer drugs, novel ruthenium(III) complexes [Ru(L)Cl(H2O)], where L is tetradentate Schiff base bis(acetylacetone)ethylendiimine…”
Get full text

Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity by Čanović, Petar, Simović, Ana Rilak, Radisavljević, Snežana, Bratsos, Ioannis, Demitri, Nicola, Mitrović, Marina, Zelen, Ivanka, Bugarčić, Živadin D.

“…With the aim of assessing how the aromaticity of the inert chelating ligand can influence the activity of ruthenium(II) polypyridyl complexes, two new…”
Get full text

New gold(III) chlorophenyl terpyridine complex: Biomolecular interactions and anticancer activity against human oral squamous cell carcinoma by Radisavljević, Snežana, Kesić, Ana, Ćoćić, Dušan, Marković, Vladimir, Milovanović, Jelena, Petrović, Biljana, Simović, Ana Rilak

“…In this work we synthesized new monofunctional gold(III) complex [Au(Cl‐Ph‐tpy)Cl]Cl2 (Cl‐Ph‐tpy = 4′‐[4‐chlorophenyl]‐2,2′:6′, 2″‐terpyridine). This complex…”
Get full text

Dinuclear ruthenium(II) polypyridyl complexes: Mechanistic study with biomolecules, DNA/BSA interactions and cytotoxic activity by Medjedović, Milica, Simović, Ana Rilak, Ćoćić, Dušan, Milutinović, Milan, Senft, Laura, Blagojević, Stefan, Milivojević, Nevena, Petrović, Biljana

“…This study confirmed that biomolecules, such as amino acids, peptides, nucleotides, DNA and proteins, might be the suitable biological targets for dinuclear…”
Get full text

In silico and in vitro biological evaluation: distribution of Ru(III) Schiff base complexes through the pancreatic 3D model and immersed blood vessel network by Međedović, Milica, Ćoćić, Dušan, Mijatović, Aleksandar, Simić, Vladimir, Milanović, Žiko, Kosanić, Marijana, Petrović, Nevena, Sretenović, Snežana, Simović, Ana Rilak

“…In this study, we describe the in vitro antimicrobial activity of newly synthesized Ru(III)-Schiff base complexes, [Ru(L)Cl(H 2 O)], where L =…”
Get full text