Search Results - "Rihon, Jérôme"

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  1. 1

    Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline by Rihon, Jérôme, Mattelaer, Charles-Alexandre, Montalvão, Rinaldo Wander, Froeyen, Mathy, Pinheiro, Vitor Bernardes, Lescrinier, Eveline

    Published in Nucleic acids research (12-04-2024)
    “…The field of synthetic nucleic acids with novel backbone structures [xenobiotic nucleic acids (XNAs)] has flourished due to the increased importance of XNA…”
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    Journal Article
  2. 2

    Synthesis, antiviral activity, and computational study of β-d-xylofuranosyl nucleoside phosphonates by Xu, Yuqing, Groaz, Elisabetta, Rihon, Jérôme, Herdewijn, Piet, Lescrinier, Eveline

    Published in European journal of medicinal chemistry (05-07-2023)
    “…Molecular dynamics (MD) simulations provided insights into the favorable interactions between xylose nucleosides bearing a phosphonate moiety at their…”
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  3. 3

    Efficient and Accurate Potential Energy Surfaces of Puckering in Sugar-Modified Nucleosides by Mattelaer, Charles-Alexandre, Mattelaer, Henri-Philippe, Rihon, Jérôme, Froeyen, Matheus, Lescrinier, Eveline

    Published in Journal of chemical theory and computation (08-06-2021)
    “…Puckering of the sugar unit in nucleosides and nucleotides is an important structural aspect that directly influences the helical structure of nucleic acids…”
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  4. 4

    Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif by Schofield, Peter, Taylor, Alexander I, Rihon, Jérôme, Peña Martinez, Cristian D, Zinn, Sacha, Mattelaer, Charles-Alexandre, Jackson, Jennifer, Dhaliwal, Gurpreet, Schepers, Guy, Herdewijn, Piet, Lescrinier, Eveline, Christ, Daniel, Holliger, Philipp

    Published in Nucleic acids research (25-08-2023)
    “…Abstract Nucleic acids not only form the basis of heredity, but are increasingly a source of novel nano-structures, -devices and drugs. This has spurred the…”
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    Journal Article
  5. 5

    Cyclic Peptides as T‑Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site by Depuydt, Anne-Sophie, Rihon, Jérôme, Cheneval, Olivier, Vanmeert, Michiel, Schroeder, Christina I, Craik, David J, Lescrinier, Eveline, Peigneur, Steve, Tytgat, Jan

    Published in ACS pharmacology & translational science (13-08-2021)
    “…T-type calcium (CaV3) channels play a crucial role in the generation and propagation of action potentials in excitable cells and are considered potential drug…”
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    Journal Article