Search Results - "Rigo, J. M."
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The anti‐epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA‐ and glycine‐gated currents
Published in British journal of pharmacology (01-07-2002)“…In this study in vitro and in vivo approaches were combined in order to investigate if the anti‐epileptic mechanism(s) of action of levetiracetam (LEV;…”
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Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks
Published in Glia (01-04-2011)“…Microglial cells invade the central nervous system during embryonic development, but their developmental functional roles in vivo remain largely unknown…”
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Glycine receptors control the generation of projection neurons in the developing cerebral cortex
Published in Cell death and differentiation (01-11-2014)“…The development of the cerebral cortex requires coordinated regulation of proliferation, specification, migration and differentiation of cortical progenitors…”
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Tonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy
Published in Molecular neurobiology (01-10-2016)“…Tonic GABA A receptors are a subpopulation of receptors that generate long-lasting inhibition and thereby control network excitability. In recent years, these…”
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Substance P protects spiral ganglion neurons from apoptosis via PKC‐Ca2+‐MAPK/ERK pathways
Published in Journal of neurochemistry (01-10-2003)“…In the current study, we have investigated the ability of substance P (SP) to protect 3‐day‐old (P3) rat spiral ganglion neurons (SGNs) from trophic factor…”
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Frequency-dependent modulation of glycine receptor activation recorded from the zebrafish larvae hindbrain
Published in Neuroscience (01-01-2006)“…In vertebrates, most glycinergic inhibitory neurons discharge phasically at a relatively low frequency. Such a pattern of glycine liberation from presynaptic…”
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Kinetic properties of the α2 homo‐oligomeric glycine receptor impairs a proper synaptic functioning
Published in The Journal of physiology (01-12-2003)“…Ionotropic glycine receptors (GlyRs) are present in the central nervous system well before the establishment of synaptic contacts. Immature nerve cells are…”
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Neurotransmitters as early signals for central nervous system development
Published in Cell and tissue research (01-08-2001)“…During brain ontogenesis, the temporal and spatial generation of the different types of neuronal and glial cells from precursors occurs as a sequence of…”
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Image analysis of neuritic regeneration by adult rat dorsal root ganglion neurons in culture: quantification of the neurotoxicity of anticancer agents and of its prevention by nerve growth factor or basic fibroblast growth factor but not brain-derived neurotrophic factor or neurotrophin-3
Published in Journal of neuroscience methods (01-07-1994)“…Peripheral neuropathies are a common side effect of chemotherapeutic agents, particularly antineoplastic drugs such as taxol, cisplatin, or vinca-alkaloids…”
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Erratum to: Tonic GABAA Receptors as Potential Target for the Treatment of Temporal Lobe Epilepsy
Published in Molecular neurobiology (01-10-2016)Get full text
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Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury
Published in Journal of neuroscience research (01-01-1993)“…In contrast to the central nervous system (CNS), the peripheral nervous system (PNS) displays an important regenerative ability which is dependent, at least in…”
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Developmental regulation of neuroligand-induced responses in cultured oligodendroglia
Published in Neuroreport (20-04-1998)“…Using whole-cell patch-clamp techniques, we show that oligosphere-derived oligodendrocyte progenitor cells (OP) display GABA-, glutamate-, 5-HT-, glycine- and…”
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Expression of growth factors and their receptors in the postnatal rat cochlea
Published in Neurochemical research (01-08-1998)“…RT-PCR was used to assay for growth factors and receptors from seven different protein families in cochlea tissues of the juvenile rat. There was a broad…”
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A Cell Type-specific and Gap Junction-independent Mechanism for the Herpes Simplex Virus-1 Thymidine Kinase Gene/Ganciclovir-mediated Bystander Effect
Published in Clinical cancer research (01-11-1999)“…Tumor cells expressing the herpes simplex virus type 1 thymidine kinase (HSV- tk ) gene are killed by nucleoside analogues such as ganciclovir (GCV). GCV…”
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Astroglia-released factor shows similar effects as benzodiazepine inverse agonists
Published in Journal of neuroscience research (01-11-1994)“…Media conditioned by cultured neonatal cerebral cortex microexplants (CCM) or astrocytes (ACM) contain low molecular weight (< 1,000 Da) substance(s) which…”
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In Vitro Ototoxicity of aminoglycosides and platin derivatives. A semi-automatic assay for sensory hair cell damage in explanted rat organ of corti
Published in Toxicology in vitro (01-12-1998)“…The ototoxic damage that drugs such as neomycin, kanamycin, colistin, cisplatin, transplatin and carboplatin cause on outer and inner hair cells in postnatal…”
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Syngeneic grafting of adult rat DRG-derived Schwann cells to the injured spinal cord
Published in Brain research bulletin (1993)“…A subdural inflatable micro-balloon was used to induce closed traumatic contusion to adult rat spinal cord. This spinal cord injury model was associated with…”
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Kainate and NMDA toxicity for cultured developing and adult rat spiral ganglion neurons: further evidence for a glutamatergic excitatory neurotransmission at the inner hair cell synapse
Published in Brain research (26-07-1991)“…In the inner ear, the excitatory amino acid glutamate is a proposed neurotransmitter acting at the synapse between hair cells and afferent auditory neurons…”
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Peripheral and central target-derived trophic factor(s) effects on auditory neurons
Published in Hearing research (01-03-1992)“…In the developing inner ear, a naturally occurring programmed cell death of cochleovestibular ganglion (CVG) neurons as well as peripheral and central…”
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Neurotransmitter-mediated regulation of CNS myelination: a review
Published in Acta neurologica Belgica (01-03-1999)“…In addition to treatments aimed at preventing or limiting damage to myelin and oligodendrocytes, there is a crucial need for repair strategies in human…”
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