Search Results - "Righi, Luisella"
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Targeted next-generation sequencing of cancer genes in advanced stage malignant pleural mesothelioma: a retrospective study
Published in Journal of thoracic oncology (01-03-2015)“…Malignant pleural mesothelioma (MPM) is a rare malignant disease, and the understanding of molecular pathogenesis has lagged behind other malignancies. A…”
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2
Role of Immunocytochemistry in the Cytological Diagnosis of Pulmonary Tumors
Published in Acta cytologica (01-01-2020)“…Pulmonary cytology is a challenging diagnostic tool, and it is usually evaluated considering medical history and radiological findings in order to reach an…”
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3
Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression
Published in The European respiratory journal (01-05-2017)“…Toll-like receptors (TLRs) and nucleotide-binding oligomerisation domain (NOD)-like receptors (NLRs) are two major forms of innate immune sensors but their…”
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4
BRCA1-Associated Protein 1 (BAP1) Immunohistochemical Expression as a Diagnostic Tool in Malignant Pleural Mesothelioma Classification: A Large Retrospective Study
Published in Journal of thoracic oncology (01-11-2016)“…Malignant pleural mesothelioma (MPM) is a highly aggressive disease with limited therapeutic options. Histological subtype remains among the most reliable…”
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5
Comparative diagnostic and prognostic performances of the hematoxylin-eosin and phospho-histone H3 mitotic count and Ki-67 index in adrenocortical carcinoma
Published in Modern pathology (01-09-2014)“…Mitotic count on hematoxylin and eosin slides is a fundamental morphological criterion in the diagnosis and grading of adrenocortical carcinoma in any scoring…”
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Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma
Published in Journal of thoracic oncology (01-08-2019)“…A comprehensive analysis of the immune cell infiltrate collected from pleural fluid and from biopsy specimens of malignant pleural mesothelioma (MPM) may…”
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Molecular and Histopathological Characterization of the Tumor Immune Microenvironment in Advanced Stage of Malignant Pleural Mesothelioma
Published in Journal of thoracic oncology (01-01-2018)“…Malignant pleural mesothelioma (MPM) is a rare, highly aggressive, and relatively chemoresistant and radioresistant malignancy with limited therapeutic…”
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8
Classification of pulmonary neuroendocrine tumors: new insights
Published in Translational lung cancer research (01-10-2017)“…Neuroendocrine tumors of the lung (Lu-NETs) embrace a heterogeneous family of neoplasms classified into four histological variants, namely typical carcinoid…”
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Thymidylate Synthase But Not Excision Repair Cross-Complementation Group 1 Tumor Expression Predicts Outcome in Patients With Malignant Pleural Mesothelioma Treated With Pemetrexed-Based Chemotherapy
Published in Journal of clinical oncology (20-03-2010)“…The relationship between thymidylate synthase (TS) expression and outcome in patients with malignant pleural mesothelioma (MPM) treated with pemetrexed (P) was…”
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10
BRAF as a positive predictive biomarker: Focus on lung cancer and melanoma patients
Published in Critical reviews in oncology/hematology (01-12-2020)“…[Display omitted] In the era of personalized medicine, BRAF mutational assessment is mandatory in advanced-stage melanoma and non-small cell lung cancer…”
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Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung
Published in Endocrine-related cancer (01-12-2010)“…Among alternative therapeutic strategies in clinically aggressive neuroendocrine tumors (NETs) of the lung, promising results have been obtained in…”
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12
Deciphering Lung Adenocarcinoma Heterogeneity: An Overview of Pathological and Clinical Features of Rare Subtypes
Published in Life (Basel, Switzerland) (31-05-2023)“…Lung cancer is one of the most frequently diagnosed cancers worldwide and the leading cause of cancer-related death. The 2021 World Health Organization (WHO)…”
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13
Human renal angiomyolipoma cells of male and female origin can migrate and are influenced by microenvironmental factors
Published in PloS one (19-06-2018)“…Improving the knowledge of angiomyolipoma physiopathology might help in refining its pharmacological treatment. We investigated if angiomyolipoma cells have…”
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14
TFEB controls sensitivity to chemotherapy and immuno-killing in non-small cell lung cancer
Published in Journal of experimental & clinical cancer research (07-08-2024)“…In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the…”
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15
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma
Published in Journal of experimental & clinical cancer research (23-02-2022)“…The combination of pemetrexed and cisplatin remains the reference first-line systemic therapy for malignant pleural mesothelioma (MPM). Its activity is…”
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Correction: TFEB controls sensitivity to chemotherapy and immuno-killing in non-small cell lung cancer
Published in Journal of experimental & clinical cancer research (29-08-2024)Get full text
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17
IκBα targeting promotes oxidative stress-dependent cell death
Published in Journal of experimental & clinical cancer research (16-04-2021)“…Oxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the…”
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Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity
Published in Journal of experimental & clinical cancer research (12-05-2023)“…MET-driven acquired resistance is emerging with unanticipated frequency in patients relapsing upon molecular therapy treatments. However, the determination of…”
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Ki-67 Evaluation for Clinical Decision in Metastatic Lung Carcinoids: A Proof of Concept
Published in Clinical pathology (Thousand Oaks, Ventura County, Calif.) (2019)“…Accrual of metastatic pulmonary carcinoid patients for therapy is usually relied on clinical and histologic characterization, with no role for the…”
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20
Primary lung adenocarcinoma in three adolescent patients affected by bone sarcomas
Published in Virchows Archiv : an international journal of pathology (01-06-2021)“…Pediatric primary lung carcinomas are extremely rare. Apart from known associations with congenital adenomatoid malformations, cases of primary lung…”
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