Search Results - "Rigatti, Lora H."

Potential pandemic risk of circulating swine H1N2 influenza viruses by Le Sage, Valerie, Rockey, Nicole C., French, Andrea J., McBride, Ryan, McCarthy, Kevin R., Rigatti, Lora H., Shephard, Meredith J., Jones, Jennifer E., Walter, Sydney G., Doyle, Joshua D., Xu, Lingqing, Barbeau, Dominique J., Wang, Shengyang, Frizzell, Sheila A., Myerburg, Michael M., Paulson, James C., McElroy, Anita K., Anderson, Tavis K., Vincent Baker, Amy L., Lakdawala, Seema S.

“…Influenza A viruses in swine have considerable genetic diversity and continue to pose a pandemic threat to humans due to a potential lack of population level…”
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Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice by Sun, Rui, Guo, Siying, Shuda, Yoko, Chakka, Anish B, Rigatti, Lora H, Zhao, Guangyi, Ali, Mohammed A E, Park, Christopher Y, Chandran, Uma, Yu, Jian, Bakkenist, Christopher J, Shuda, Masahiro, Moore, Patrick S, Chang, Yuan

“…4E-BP1 is a tumor suppressor regulating cap-dependent translation that is in turn controlled by mechanistic target of rapamycin (mTOR) or cyclin-dependent…”
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Pericytes reduce inflammation and collagen deposition in acute wounds by BODNAR, RICHARD J, YANG, TIANBING, RIGATTI, LORA H, LIU, FANG, EVDOKIOU, ALEXANDER, KATHJU, SANDEEP, SATISH, LATHA

“…Abstract Background Pericytes have been shown to have mesenchymal stromal cell–like properties and play a role in tissue regeneration. The goal of this study…”
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Clostridium difficile Enterocolitis in a Captive Geoffroy’s Spider Monkey (Ateles geoffroyi) and Common Marmosets (Callithrix jacchus) by Armstrong, Alexandra R., Wünschmann, Arno, Rigatti, Lora H., Klein, Edwin C.

“…Clostridium difficile is a well-documented cause of enterocolitis in several species, including humans, with limited documentation in New World nonhuman…”
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EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer by Pascal, Laura E., Wang, Yao, Zhong, Mingming, Wang, Dan, Chakka, Anish Bhaswanth, Yang, Zhenyu, Li, Feng, Song, Qiong, Rigatti, Lora H., Chaparala, Srilakshmi, Chandran, Uma, Parwani, Anil V., Wang, Zhou

“…The tumor suppressor genes EAF2 and p53 are frequently dysregulated in prostate cancers. Recently, we reported that concurrent p53 nuclear staining and EAF2…”
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Evaluating inflammation in an obstruction‐based chronic rhinosinusitis model in rabbits by Schilling, Andrea L., Moore, John, Kulahci, Yalcin, Little, Steven R., Rigatti, Lora H., Wang, Eric W., Lee, Stella E.

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Evaluation of the pharmacokinetics, dosimetry, and therapeutic efficacy for the α-particle-emitting transarterial radioembolization (αTARE) agent [225Ac]Ac-DOTA-TDA-Lipiodol® against hepatic tumors by Josefsson, Anders, Cortez, Angel G., Rajkumar, Harikrishnan, Latoche, Joseph D., Jaswal, Ambika P., Day, Kathryn E., Zarisfi, Mohammadreza, Rigatti, Lora H., Huang, Ziyu, Nedrow, Jessie R.

“…Background The liver is a common site for metastatic disease for a variety of cancers, including colorectal cancer. Both primary and secondary liver tumors are…”
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Identification and Characterization of Novel Rat Polyomavirus 2 in a Colony of X-SCID Rats by P-PIT assay by Rigatti, Lora H, Toptan, Tuna, Newsome, Joseph T, Moore, Patrick S, Chang, Yuan

“…Polyomaviruses (PyVs) are known to infect a wide range of vertebrates and invertebrates and are associated with a broad spectrum of diseases, including…”
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Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice by Pascal, Laura E, Ai, Junkui, Masoodi, Khalid Z, Wang, Yujuan, Wang, Dan, Eisermann, Kurtis, Rigatti, Lora H, O'Malley, Katherine J, Ma, Hei M, Wang, Xinhui, Dar, Javid A, Parwani, Anil V, Simons, Brian W, Ittman, Michael M, Li, Luyuan, Davies, Benjamin J, Wang, Zhou

“…ELL-associated factor 2 (EAF2) is an androgen-responsive tumor suppressor frequently deleted in advanced prostate cancer that functions as a transcription…”
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Chemical Carcinogen (3-Methylcholanthrene)-induced Pleomorphic Rhabdomyosarcomas in Fanconi Anemia Fancd2-/-, Fancg-/- (C57BL/6), Fancd2-/- (129/Sv) Mice by Fisher, Renee, Epperly, Michael W, Rigatti, Lora H, Shields, Donna, Greenberger, Joel S, Green, Anthony, Mukherjee, Amitava

“…Radiation oncologists are reluctant to treat cancer in Fanconi Anemia (FA) patients due to their lack of homologous recombination repair of DNA strand breaks…”
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Prostate-Specific Deletion of Cdh1 Induces Murine Prostatic Inflammation and Bladder Overactivity by Pascal, Laura E, Mizoguchi, Shinsuke, Chen, Wei, Rigatti, Lora H, Igarashi, Taro, Dhir, Rajiv, Tyagi, Pradeep, Wu, Zeyu, Yang, Zhenyu, de Groat, William C, DeFranco, Donald B, Yoshimura, Naoki, Wang, Zhou

“…Abstract Benign prostatic hyperplasia (BPH) is an age-related debilitating prostatic disease that is frequently associated with prostatic inflammation and…”
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Chemical Carcinogen (Dimethyl-benzanthracene) Induced Transplantable Cancer in Fanconi Anemia (Fanca-/-) Mice by Epperly, Michael W, Mukherjee, Amitava, Fisher, Renee, Shields, Donna, Hou, Wen, Wang, Hong, Rigatti, Lora H, Green, Anthony, Huq, M Saiful, Greenberger, Joel S

“…Patients with radiation sensitive Fanconi anemia (FA) are presenting with cancers of the oral cavity, oropharynx, and other anatomic locations. Animal models…”
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Mitigation of Fetal Radiation Injury from Mid-Gestation Total-body Irradiation by Maternal Administration of Mitochondrial-Targeted GS-Nitroxide JP4-039 by Wu, Yijen L., Christodoulou, Anthony G., Beumer, Jan H., Rigatti, Lora H., Fisher, Renee, Ross, Mark, Watkins, Simon, Cortes, Devin R. E., Ruck, Cody, Manzoor, Shanim, Wyman, Samuel K., Stapleton, Margaret C., Goetzman, Eric, Bharathi, Sivakama, Wipf, Peter, Wang, Hong, Tan, Tuantuan, Christner, Susan M., Guo, Jianxia, Lo, Cecilia W. Y., Epperly, Michael W., Greenberger, Joel S.

“…Victims of a radiation terrorist event will include pregnant women and unborn fetuses. Mitochondrial dysfunction and oxidative stress are key pathogenic…”
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E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice by Pascal, Laura E, Igarashi, Taro, Mizoguchi, Shinsuke, Chen, Wei, Rigatti, Lora H, Madigan, Caroline G, Dhir, Rajiv, Bushman, Wade, DeFranco, Donald B, Yoshimura, Naoki, Wang, Zhou

“…Decreased E-cadherin immunostaining is frequently observed in benign prostatic hyperplasia (BPH) and was recently correlated with increased inflammation in…”
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Experimental respiratory exposure to putative Gulf War toxins promotes persistent alveolar macrophage recruitment and pulmonary inflammation by Powers, Amy A., Jones, Katherine E., Eisenberg, Seth H., Rigatti, Lora H., Ryan, John P., Luketich, James D., Lotze, Michael T., LaRue, Amanda C., Dhupar, Rajeev, Soloff, Adam C.

“…Respiratory disorders are a prominent component of Gulf War Illness. Although much of the underlying mechanisms of Gulf War Illness remain undefined, chronic…”
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Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging by Robinson, Andria R., Yousefzadeh, Matthew J., Rozgaja, Tania A., Wang, Jin, Li, Xuesen, Tilstra, Jeremy S., Feldman, Chelsea H., Gregg, Siobhán Q., Johnson, Caroline H., Skoda, Erin M., Frantz, Marie-Céline, Bell-Temin, Harris, Pope-Varsalona, Hannah, Gurkar, Aditi U., Nasto, Luigi A., Robinson, Renã A.S., Fuhrmann-Stroissnigg, Heike, Czerwinska, Jolanta, McGowan, Sara J., Cantu-Medellin, Nadiezhda, Harris, Jamie B., Maniar, Salony, Ross, Mark A., Trussoni, Christy E., LaRusso, Nicholas F., Cifuentes-Pagano, Eugenia, Pagano, Patrick J., Tudek, Barbara, Vo, Nam V., Rigatti, Lora H., Opresko, Patricia L., Stolz, Donna B., Watkins, Simon C., Burd, Christin E., Croix, Claudette M. St, Siuzdak, Gary, Yates, Nathan A., Robbins, Paul D., Wang, Yinsheng, Wipf, Peter, Kelley, Eric E., Niedernhofer, Laura J.

“…Accumulation of senescent cells over time contributes to aging and age-related diseases. However, what drives senescence in vivo is not clear. Here we used a…”
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Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice by Pascal, Laura E., Su, Fei, Wang, Dan, Ai, Junkui, Song, Qiong, Wang, Yujuan, O'Malley, Katherine J., Cross, Brian, Rigatti, Lora H., Green, Anthony, Dhir, Rajiv, Wang, Zhou

“…ELL-associated factor 1 is a transcription elongation factor that shares significant homology and functional similarity to the androgen-responsive prostate…”
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Preclinical Dosimetry, Imaging, and Targeted Radionuclide Therapy Studies of Lu-177-Labeled Albumin-Binding, PSMA-Targeted CTT1403 by Ling, Xiaoxi, Latoche, Joseph D., Choy, Cindy J., Kurland, Brenda F., Laymon, Charles M., Wu, Yijen, Salamacha, Nathan, Shen, Ding, Geruntho, Jonathan J., Rigatti, Lora H., Windish, Hillarie P., Langton-Webster, Beatrice, Berkman, Clifford E., Anderson, Carolyn J.

“…Purpose Prostate-specific membrane antigen (PSMA) continues to be the hallmark biomarker for prostate cancer as it is expressed on nearly all prostatic tumors…”
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Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate by Singh, Krishna B, Hahm, Eun-Ryeong, Rigatti, Lora H, Normolle, Daniel P, Yuan, Jian-Min, Singh, Shivendra V

“…We have shown previously that dietary administration of phenethyl isothiocyanate (PEITC), a small molecule from edible cruciferous vegetables, significantly…”
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Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression by Rolyan, Harshvardhan, Tyurina, Yulia Y, Hernandez, Marylens, Amoscato, Andrew A, Sparvero, Louis J, Nmezi, Bruce C, Lu, Yue, Estécio, Marcos R H, Lin, Kevin, Chen, Junda, He, Rong-Rong, Gong, Pin, Rigatti, Lora H, Dupree, Jeffrey, Bayır, Hülya, Kagan, Valerian E, Casaccia, Patrizia, Padiath, Quasar S

“…Lamin B1 is a component of the nuclear lamina and plays a critical role in maintaining nuclear architecture, regulating gene expression and modulating…”
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