Search Results - "Rifon, Jose"

Impact of spleen size and splenectomy on outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis: A retrospective analysis by the chronic malignancies working party on behalf of European society for blood and marrow transplantation (EBMT) by Polverelli, Nicola, Mauff, Katya, Kröger, Nicolaus, Robin, Marie, Beelen, Dietrich, Beauvais, David, Chevallier, Patrice, Mohty, Mohamad, Passweg, Jakob, Rubio, Marie Thérèse, Maertens, Johan, Finke, Jürgen, Bornhäuser, Martin, Vrhovac, Radovan, Helbig, Grzegorz, Mear, Jean‐Baptiste, Castagna, Luca, Reményi, Péter, Angelucci, Emanuele, Karakasis, Dimitrios, Rifòn, Jose, Sirait, Tiarlan, Russo, Domenico, Wreede, Liesbeth, Czerw, Tomasz, Hernández‐Boluda, Juan Carlos, Hayden, Patrick, McLornan, Donal, Yakoub‐Agha, Ibrahim

“…The role of spleen size and splenectomy for the prediction of post‐allogeneic hematopoietic stem cell transplant (allo‐HCT) outcome in myelofibrosis remains…”
Get full text

Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a phase I/II clinical trial by PEREZ-SIMON, Jose A, LOPEZ-VILLAR, Olga, ANDREU, Enrique J, RIFON, Jose, MUNTION, Sandra, CAMPELO, María Diez, SANCHEZ-GUIJO, Fermin M, MARTINEZ, Carmen, VALCARCEL, David, DEL CANIZO, Consuelo

“…This trial evaluated the feasibility and efficacy of the infusion of mesenchymal stem cells expanded using human serum for the treatment of refractory acute or…”
Get full text

Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated by Martínez-Calle, Nicolás, Pascual, Marien, Ordoñez, Raquel, Enériz, Edurne San José, Kulis, Marta, Miranda, Estíbaliz, Guruceaga, Elisabeth, Segura, Víctor, Larráyoz, María José, Bellosillo, Beatriz, Calasanz, María José, Besses, Carles, Rifón, José, Martín-Subero, José I, Agirre, Xabier, Prosper, Felipe

“…In this study we interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially…”
Get full text

A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia by Arriazu, Elena, Vicente, Carmen, Pippa, Raffaella, Peris, Irene, Martínez-Balsalobre, Elena, García-Ramírez, Patricia, Marcotegui, Nerea, Igea, Ana, Alignani, Diego, Rifón, José, Mateos, María C., Cayuela, María L., Nebreda, Angel R., Odero, María D.

“…Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new…”
Get full text

Bendamustine as part of conditioning of autologous stem cell transplantation in patients with aggressive lymphoma: a phase 2 study from the GELTAMO group by Redondo, Alba M., Valcárcel, David, González‐Rodríguez, Ana P., Suárez‐Lledó, María, Bello, José L., Canales, Miguel, Gayoso, Jorge, Colorado, Mercedes, Jarque, Isidro, Campo, Raquel, Arranz, Reyes, Terol, María J., Rifón, José J., Rodríguez, María J., Ramírez, María J, Castro, Nerea, Sánchez, Andrés, López‐Jiménez, Javier, Montes‐Moreno, Santiago, Briones, Javier, López, Aurelio, Palomera, Luis, López‐Guillermo, Armando, Caballero, Dolores, Martín, Alejandro

“…Summary We conducted a phase 2 trial to evaluate the safety and efficacy of bendamustine instead of BCNU (carmustine) in the BEAM (BCNU, etoposide, cytarabine…”
Get full text

SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia by Cristóbal, Ion, Blanco, Francisco J., Garcia-Orti, Laura, Marcotegui, Nerea, Vicente, Carmen, Rifon, José, Novo, Francisco J., Bandres, Eva, Calasanz, María J., Bernabeu, Carmelo, Odero, María D.

“…Acute myeloid leukemias (AMLs) result from multiple genetic alterations in hematopoietic stem cells. We describe a novel t(12;18)(p13;q12) involving ETV6 in a…”
Get full text

First‐line use of rituximab correlates with increased overall survival in late post‐transplant lymphoproliferative disorders: retrospective, single‐centre study by Martínez‐Calle, Nicolás, Alfonso, Ana, Rifón, José, Herrero, Ignacio, Errasti, Pedro, Rábago, Gregorio, Merino, Juana, Panizo, Ángel, Pardo, Javier, Prósper, Felipe, García‐Muñoz, Ricardo, Lecumberri, Ramón, Panizo, Carlos

“…This retrospective study evaluates the impact of rituximab on PTLD response and survival in a single‐centre cohort. PTLD cases between 1984 and 2009, including…”
Get full text

Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia by Calviño, Cristina, Ceballos, Candela, Alfonso, Ana, Jauregui, Patricia, Calleja-Cervantes, Maria E, San Martin-Uriz, Patxi, Rodriguez-Marquez, Paula, Martin-Mallo, Angel, Iglesias, Elena, Abizanda, Gloria, Rodriguez-Diaz, Saray, Martinez-Turrillas, Rebeca, Illarramendi, Jorge, Viguria, Maria C, Redondo, Margarita, Rifon, Jose, Villar, Sara, Lasarte, Juan J, Inoges, Susana, Lopez-Diaz de Cerio, Ascension, Hernaez, Mikel, Prosper, Felipe, Rodriguez-Madoz, Juan R

“…Despite the potential of CAR-T therapies for hematological malignancies, their efficacy in patients with relapse and refractory Acute Myeloid Leukemia has been…”
Get full text

Treatment of graft-versus-host disease with mesenchymal cells as a complication of a liver transplantation by Mora, Lorena, Alegre, Félix, Rifón, José Juan, Martí, Pablo, Herrero, José Ignacio

“…We present the case of a liver transplant (LT) recipient donor who developed graft versus host disease (GVHD). The main features were cutaneous rash, diarrhea…”
Get full text

Deregulation of FGFR1 and CDK6 oncogenic pathways in acute lymphoblastic leukaemia harbouring epigenetic modifications of the MIR9 family by Rodriguez‐Otero, Paula, Román‐Gómez, José, Vilas‐Zornoza, Amaia, José‐Eneriz, Edurne San, Martín‐Palanco, Vanesa, Rifón, José, Torres, Antonio, Calasanz, María José, Agirre, Xabier, Prosper, Felipe

“…Summary The role of epigenetic mechanisms in the regulation of microRNAs (miRNAs) with a tumour‐suppressor function in human neoplasms has recently been…”
Get full text

Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia by Vilas-Zornoza, Amaia, Agirre, Xabier, Martín-Palanco, Vanesa, Martín-Subero, José Ignacio, San José-Eneriz, Edurne, Garate, Leire, Álvarez, Sara, Miranda, Estíbaliz, Rodríguez-Otero, Paula, Rifón, José, Torres, Antonio, Calasanz, María José, Cruz Cigudosa, Juan, Román-Gómez, José, Prósper, Felipe

“…Aberrant DNA methylation is one of the most frequent alterations in patients with Acute Lymphoblastic Leukemia (ALL). Using methylation bead arrays we analyzed…”
Get full text

Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia by Ruggeri, Annalisa, Galimard, Jacques-Emmanuel, Paina, Olesya, Fagioli, Franca, Tbakhi, Abdelghani, Yesilipek, Akif, Navarro, José Maria Fernandez, Faraci, Maura, Hamladji, Rose-Marie, Skorobogatova, Elena, Al-Seraihy, Amal, Sundin, Mikael, Herrera, Concepcion, Rifón, Jose, Dalissier, Arnaud, Locatelli, Franco, Rocha, Vanderson, Corbacioglu, Selim

“…HLA-haploidentical transplantation (haplo-HCT) using post-transplantation-cyclophosphamide (PT-Cy) is a feasible procedure in children with malignancies…”
Get full text

Engraftment after autologous hematopoietic stem cell transplantation in patients mobilized with Plerixafor: A retrospective, multicenter study of a large series of patients by Antelo, M. Luisa, Altuna, Ane, Gimeno, J. José, Ferreiro, J. Javier, Amunárriz, Cristina, Mateos, J. José, Zalba, Saioa, Alkorta, Aitziber, Rifón, José, Arroyo, J. Luis, Uresandi, Amaia, Moreno, J. Antonio, Nájera, M. Josefa, Pinzón, Sergio, García, Alejandro, Vallejo, J. Carlos

“…•Plerixafor (PLX) enhances hematopoietic stem-cell mobilization for transplantation.•Data on the quality of engraftment after mobilization with PLX is…”
Get full text

Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma by Palacios-Berraquero, Maria Luisa, Rodriguez-Marquez, Paula, Calleja-Cervantes, Maria Erendira, Berastegui, Nerea, Zabaleta, Aintzane, Burgos, Leire, Alignani, Diego, San Martin-Uriz, Patxi, Vilas-Zornoza, Amaia, Rodriguez-Diaz, Saray, Inoges, Susana, Lopez-Diaz de Cerio, Ascensión, Huerga, Sofia, Tamariz, Esteban, Rifon, Jose, Alfonso-Pierola, Ana, Lasarte, Juan Jose, Paiva, Bruno, Hernaez, Mikel, Rodriguez-Otero, Paula, San-Miguel, Jesus, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Prosper, Felipe

“…•Long-lasting cytopenia after BCMA CAR-T therapy correlates with baseline cytopenia and peak inflammatory markers.•Supernatants from activated BCMA CAR-Ts…”
Get full text

Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC) by Galán, Victor, Beléndez, Cristina, Echecopar, Carlos, Estival, Pablo, Sissini, Luisa, Olivas, Raquel, Bueno, David, Molina, Blanca, Fuentes, Carolina, Regueiro, Alexandra, Benítez, Isabel, Plaza, Mercedes, Margarit, Adriana, Rifón, José, Pascual, Antonia, Palomo, Pilar, Urtasun, Andrea, Fuster, José Luis, Díaz de Heredia, Cristina, Fernández Navarro, José María, González-Vicent, Marta, Ruz, Beatriz, Pérez-Martínez, Antonio

“…Increasing data on treosulfan-based conditioning regimens before hematopoietic stem cell transplantation (HSCT) demonstrate the consistent benefits of this…”
Get full text

Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation by Heilig, Christoph E, Badoglio, Manuela, Labopin, Myriam, Fröhling, Stefan, Secondino, Simona, Heinz, Jürgen, Nicolas-Virelizier, Emmanuelle, Blaise, Didier, Korenbaum, Clément, Santoro, Armando, Verbeek, Mareike, Krüger, William, Siena, Salvatore, Passweg, Jakob R, Di Nicola, Massimo, Rifón, Jose, Dreger, Peter, Koehl, Ulrike, Chabannon, Christian, Pedrazzoli, Paolo

“…BackgroundThe role of high-dose chemotherapy with autologous stem cell transplantation (ASCT) in the treatment of soft-tissue sarcoma (STS) remains an…”
Get full text

The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells by Viñado, Ana C., Calvo, Isabel A., Cenzano, Itziar, Olaverri, Danel, Cocera, Miguel, San Martin-Uriz, Patxi, Romero, Juan P., Vilas-Zornoza, Amaia, Vera, Laura, Gomez-Cebrian, Nuria, Puchades-Carrasco, Leonor, Lisi-Vega, Livia E., Apaolaza, Iñigo, Valera, Pablo, Guruceaga, Elisabeth, Granero-Molto, Froilan, Ripalda-Cemborain, Purificacion, Luck, Tamara J., Bullinger, Lars, Planes, Francisco J., Rifon, José J., Méndez-Ferrer, Simón, Yusuf, Rushdia Z., Pardo-Saganta, Ana, Prosper, Felipe, Saez, Borja

“…Eradicating leukemia requires a deep understanding of the interaction between leukemic cells and their protective microenvironment. The CXCL12/CXCR4 axis has…”
Get full text

Response to Novel Drugs before and after Allogeneic Stem Cell Transplantation in Patients with Relapsed Multiple Myeloma by López-Corral, Lucia, Caballero-Velázquez, Teresa, López-Godino, Oriana, Rosiñol, Laura, Pérez-Vicente, Sabina, Fernandez-Avilés, Francesc, Krsnik, Isabel, Morillo, Daniel, Heras, Inmaculada, Morgades, Mireia, Rifon, Jose J., Sampol, Antonia, Iniesta, Francisca, Ocio, Enrique-María, Martin, Jesús, Rovira, Montserrat, Cabero, Martín, Castilla-Llorente, Cristina, Ribera, Josep-María, Torres-Juan, Marta, Moraleda, Jose María, Martinez, Carmen, Vázquez, Alejandro, Gutierrez, Gonzalo, Caballero, Dolores, San Miguel, Jesús F., Mateos, María-Victoria, Pérez-Simón, Jose Antonio

“…•Treatment regimens based on proteasome inhibitors and immunomodulatory drugs are effective and safe after allogeneic hematopoietic stem cell transplantation…”
Get full text

BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells by Andreu, Enrique J, Lledó, Elisa, Poch, Enric, Ivorra, Carmen, Albero, M Pilar, Martínez-Climent, José Angel, Montiel-Duarte, Cristina, Rifón, José, Pérez-Calvo, Javier, Arbona, Cristina, Prósper, Felipe, Pérez-Roger, Ignacio

“…Chronic myelogenous leukemia (CML) is characterized by the expression of the BCR-ABL tyrosine kinase, which results in increased cell proliferation and…”
Get full text

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia by Pérez, Cristina, Martínez-Calle, Nicolas, Martín-Subero, José Ignacio, Segura, Victor, Delabesse, Eric, Fernandez-Mercado, Marta, Garate, Leire, Alvarez, Sara, Rifon, José, Varea, Sara, Boultwood, Jacqueline, Wainscoat, James S, Cruz Cigudosa, Juan, Calasanz, María José, Cross, Nicholas C P, Prósper, Felipe, Agirre, Xabier

“…Chronic myelomonocytic leukemia (CMML) has recently been associated with a high incidence of diverse mutations in genes such as TET2 or EZH2 that are…”
Get full text