Search Results - "Riffle, Lisa"
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Growth factor dependency in mammary organoids regulates ductal morphogenesis during organ regeneration
Published in Scientific reports (03-05-2022)“…Signaling pathways play an important role in cell fate determination in stem cells and regulate a plethora of developmental programs, the dysregulation of…”
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3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor
Published in Journal of translational medicine (18-08-2022)“…Abstract Background Several new generation CDK4/6 inhibitors have been developed and approved for breast cancer therapy in combination with endocrine…”
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3
Subcutaneous Alfaxalone-Xylazine-Buprenorphine for Surgical Anesthesia and Echocardiographic Evaluation of Mice (Mus musculus)
Published in Journal of the American Association for Laboratory Animal Science (01-01-2024)“…Alfaxalone is a commonly used injectable anesthetic in dogs and cats due to its minimal cardiovascular side effects. Data for its use in mice are limited and…”
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4
Subcutaneous Alfaxalone-XylazineBuprenorphine for Surgical Anesthesia and Echocardiographic Evaluation of Mice (Mus musculus)
Published in Journal of the American Association for Laboratory Animal Science (01-01-2024)“…Alfaxalone is a commonly used injectable anesthetic in dogs and cats due to its minimal cardiovascular side effects. Data for its use in mice are limited and…”
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5
A spontaneously metastatic model of bladder cancer: imaging characterization
Published in Journal of translational medicine (19-12-2019)“…Spontaneously metastatic xenograft models of cancer are infrequent and the few that exist are resource intensive. In xenografts, caliper measurements can be…”
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6
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma
Published in Cancers (25-06-2024)“…Activating mutations in the RAS/MAPK pathway are observed in relapsed neuroblastoma. Preclinical studies indicate that these tumors have an increased…”
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7
In vivo MRI virtual colonography in a mouse model of colon cancer
Published in Nature protocols (01-11-2014)“…Magnetic resonance colonography (MRC) can be used to monitor colonic tumors and mucosal inflammation. This protocol describes the use of a Fluorinert enema…”
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8
Zirconium-89 labeled panitumumab: a potential immuno-PET probe for HER1-expressing carcinomas
Published in Nuclear medicine and biology (01-05-2013)“…Abstract Introduction Anti-HER1 monoclonal antibody (mAb), panitumumab (Vectibix) is a fully human mAb approved by the FDA for the treatment of epidermal…”
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9
Monitoring of Tumor Promotion and Progression in a Mouse Model of Inflammation-Induced Colon Cancer with Magnetic Resonance Colonography
Published in Neoplasia (New York, N.Y.) (01-03-2009)“…Early detection of precancerous tissue has significantly improved survival of most cancers including colorectal cancer (CRC). Animal models designed to study…”
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10
Imaging the Met Receptor Tyrosine Kinase (Met) and Assessing Tumor Responses to a Met Tyrosine Kinase Inhibitor in Human Xenograft Mouse Models with a [99mTc] (AH-113018) or CY 5 (AH-112543) Labeled Peptide
Published in Molecular imaging (01-09-2015)“…Developing an imaging agent targeting the hepatocyte growth factor receptor protein (Met) status of cancerous lesions would aid in the diagnosis and monitoring…”
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11
Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence
Published in PloS one (12-07-2011)“…Gene rearrangement occurs during development in some cell types and this genome dynamics is modulated by intrinsic and extrinsic factors, including growth…”
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12
Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines
Published in Nature methods (01-03-2022)“…Recent progress has shown that using wavelengths between 1,000 and 2,000 nm, referred to as the shortwave-infrared or near-infrared (NIR)-II range, can enable…”
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13
Abstract 3007: Imaging characterization of NCI patient derived model repository (PDMR) xenografts
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract The purpose of this work is to provide imaging data on patient derived xenografts models that are available from the National Cancer Institute…”
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Imaging characterization of National Cancer Institute patient derived xenograft models
Published in Nuclear medicine and biology (01-05-2022)Get full text
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P-249 - Imaging characterization of National Cancer Institute patient derived xenograft models
Published in Nuclear medicine and biology (01-05-2022)Get full text
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16
A dual-luciferase bioluminescence system for the assessment of cellular therapies
Published in Molecular Therapy: Oncology (21-03-2024)“…Bioluminescence imaging is a well-established platform for evaluating engineered cell therapies in preclinical studies. However, despite the discovery of new…”
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17
Preconceptional fasting of fathers alters serum glucose in offspring of mice
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2006)“…Maternal nutrition has long-term effects on offspring characteristics. Similar effects mediated through fathers have not been tested. Outbred Swiss male mice…”
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Abstract 986: The National Cancer Institute's patient-derived models repository (PDMR)
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract The National Cancer Institute (NCI) has developed a Patient-Derived Models Repository (PDMR) comprised of quality-controlled, early-passage,…”
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A New Approach in the Preparation of Dendrimer-Based Bifunctional Diethylenetriaminepentaacetic Acid MR Contrast Agent Derivatives
Published in Bioconjugate chemistry (15-07-2009)“…In this paper, we report a new method to prepare and characterize a contrast agent based on a fourth-generation (G4) polyamidoamine (PAMAM) dendrimer…”
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20
Imaging the Met Receptor Tyrosine Kinase (Met) and Assessing Tumor Responses to a Met Tyrosine Kinase Inhibitor in Human Xenograft Mouse Models with a 99mTc (AH-113018) or Cy 5 (AH-112543) Labeled Peptide
Published in Molecular imaging (01-01-2015)“…Developing an imaging agent targeting the hepatocyte growth factor receptor protein (Met) status of cancerous lesions would aid in the diagnosis and monitoring…”
Get full text
Journal Article