Search Results - "Rifatbegovic, Fikret"

Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8 by Weiss, Tamara, Taschner-Mandl, Sabine, Janker, Lukas, Bileck, Andrea, Rifatbegovic, Fikret, Kromp, Florian, Sorger, Helena, Kauer, Maximilian O., Frech, Christian, Windhager, Reinhard, Gerner, Christopher, Ambros, Peter F., Ambros, Inge M.

“…Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity allows SCs to acquire repair-specific functions essential for peripheral nerve…”
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Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis by Fetahu, Irfete S., Esser-Skala, Wolfgang, Dnyansagar, Rohit, Sindelar, Samuel, Rifatbegovic, Fikret, Bileck, Andrea, Skos, Lukas, Bozsaky, Eva, Lazic, Daria, Shaw, Lisa, Tötzl, Marcus, Tarlungeanu, Dora, Bernkopf, Marie, Rados, Magdalena, Weninger, Wolfgang, Tomazou, Eleni M., Bock, Christoph, Gerner, Christopher, Ladenstein, Ruth, Farlik, Matthias, Fortelny, Nikolaus, Taschner-Mandl, Sabine

“…Metastasis is the major cause of cancer-related deaths. Neuroblastoma (NB), a childhood tumor has been molecularly defined at the primary cancer site, however,…”
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Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype by Weiss, Tamara, Taschner-Mandl, Sabine, Bileck, Andrea, Slany, Astrid, Kromp, Florian, Rifatbegovic, Fikret, Frech, Christian, Windhager, Reinhard, Kitzinger, Hugo, Tzou, Chieh-Han, Ambros, Peter F., Gerner, Christopher, Ambros, Inge M.

“…The remarkable feature of Schwann cells (SCs) to transform into a repair phenotype turned the spotlight on this powerful cell type. SCs provide the…”
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Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation by Kirchberger, Stefanie, Shoeb, Mohamed R., Lazic, Daria, Wenninger-Weinzierl, Andrea, Fischer, Kristin, Shaw, Lisa E., Nogueira, Filomena, Rifatbegovic, Fikret, Bozsaky, Eva, Ladenstein, Ruth, Bodenmiller, Bernd, Lion, Thomas, Traver, David, Farlik, Matthias, Schöfer, Christian, Taschner-Mandl, Sabine, Halbritter, Florian, Distel, Martin

“…Neutrophils are evolutionarily conserved innate immune cells playing pivotal roles in host defense. Zebrafish models have contributed substantially to our…”
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An annotated fluorescence image dataset for training nuclear segmentation methods by Kromp, Florian, Bozsaky, Eva, Rifatbegovic, Fikret, Fischer, Lukas, Ambros, Magdalena, Berneder, Maria, Weiss, Tamara, Lazic, Daria, Dörr, Wolfgang, Hanbury, Allan, Beiske, Klaus, Ambros, Peter F., Ambros, Inge M., Taschner-Mandl, Sabine

“…Fully-automated nuclear image segmentation is the prerequisite to ensure statistically significant, quantitative analyses of tissue preparations,applied in…”
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Impact of Disseminated Neuroblastoma Cells on the Identification of the Relapse-Seeding Clone by Abbasi, M Reza, Rifatbegovic, Fikret, Brunner, Clemens, Mann, Georg, Ziegler, Andrea, Pötschger, Ulrike, Crazzolara, Roman, Ussowicz, Marek, Benesch, Martin, Ebetsberger-Dachs, Georg, Chan, Godfrey C F, Jones, Neil, Ladenstein, Ruth, Ambros, Inge M, Ambros, Peter F

“…Tumor relapse is the most frequent cause of death in stage 4 neuroblastomas. Since genomic information on the relapse precursor cells could guide targeted…”
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Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies-A Validation Study by Rifatbegovic, Fikret, Abbasi, M Reza, Taschner-Mandl, Sabine, Kauer, Maximilian, Weinhäusel, Andreas, Handgretinger, Rupert, Ambros, Peter F

“…Metastases in the bone marrow (BM) in form of disseminated tumor cells (DTCs) are frequent events at diagnosis and also at relapse in high-risk neuroblastoma…”
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VP2: Schwann Cells Regulate Neuronal Differentiation by Epidermal Growth Factor-Like Protein 8 by Weiss, Tamara, Taschner-Mandl, Sabine, Janker, Lukas, Bileck, Andrea, Rifatbegovic, Fikret, Kromp, Florian, Sorger, Helena, Kauer, Maximilian O., Frech, Christian, Windhager, Reinhard, Gerner, Christopher, Ambros, Peter F., Ambros, Inge M.

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Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro by Berner, Jakob, Weiss, Tamara, Sorger, Helena, Rifatbegovic, Fikret, Kauer, Max, Windhager, Reinhard, Dohnal, Alexander, Ambros, Peter F., Ambros, Inge M., Boztug, Kaan, Steinberger, Peter, Taschner‐Mandl, Sabine

“…The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system…”
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Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression by Rifatbegovic, Fikret, Frech, Christian, Abbasi, M. Reza, Taschner‐Mandl, Sabine, Weiss, Tamara, Schmidt, Wolfgang M., Schmidt, Iris, Ladenstein, Ruth, Ambros, Inge M., Ambros, Peter F.

“…Neuroblastoma is the most common extracranial solid tumor in childhood. The vast majority of metastatic (M) stage patients present with disseminated tumor…”
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Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging by Lazic, Daria, Kromp, Florian, Rifatbegovic, Fikret, Repiscak, Peter, Kirr, Michael, Mivalt, Filip, Halbritter, Florian, Bernkopf, Marie, Bileck, Andrea, Ussowicz, Marek, Ambros, Inge M, Ambros, Peter F, Gerner, Christopher, Ladenstein, Ruth, Ostalecki, Christian, Taschner-Mandl, Sabine

“…While the bone marrow attracts tumor cells in many solid cancers leading to poor outcome in affected patients, comprehensive analyses of bone marrow metastases…”
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Abstract A38: RNA-seq of diagnostic and relapse disseminated tumor cells (DTCs) in stage M neuroblastoma patients and first steps towards DTC-derived xenografts in zebrafish embryos by Rifatbegovic, Fikret, Taschner-Mandl, Sabine, Distel, Martin, Abbasi, M. Reza, Frech, Christian, Ziegler, Andrea, Ambros, Inge M., Ambros, Peter F.

“…Neuroblastoma (NB) is the most common tumor diagnosed in the first year of life. More than 90% of stage M NB patients present with disseminated tumor cells…”
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Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence by Taschner-Mandl, Sabine, Schwarz, Magdalena, Blaha, Johanna, Kauer, Maximilian, Kromp, Florian, Frank, Nelli, Rifatbegovic, Fikret, Weiss, Tamara, Ladenstein, Ruth, Hohenegger, Martin, Ambros, Inge M, Ambros, Peter F

“…Poor prognosis and frequent relapses are major challenges for patients with high-risk neuroblastoma (NB), especially when tumors show MYCN amplification…”
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Abstract A17: Metronomic topotecan causes MYCN inactivation and impedes tumor growth selectively in MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy-induced senescence by Taschner-Mandl, Sabine, Gerber, Teresa, Schwarz, Magdalena, Blaha, Johanna, Kauer, Maximilian, Kromp, Florian, Frank, Nelli, Rifatbegovic, Fikret, Weiss, Tamara, Ladenstein, Ruth, Hohenegger, Martin, Ambros, Inge M., Ambros, Peter F.

“…Background: Poor prognosis and frequent relapses are major challenges for patients with high-risk neuroblastoma (NB), especially when tumors show MYCN…”
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Abstract 5344: High-throughput CRISPR-Cas9 knockout screens identify loss of miRNA1304-5p targeting the RAS/MAPK pathway as a modulator of resistance to ALK inhibitors in high-risk neuroblastoma by Pucci, Perla, Lee, Liam, Turner, Suzanne, Jahangiri, Leila, Matthews, Jamie, Burke, Amos, Reynolds, Patrick, Kenner, Lukas, Merkel, Olaf, Rifatbegovic, Fikret, Luo, Ji, Ambros, Peter, Han, MiaoJun

“…Anaplastic lymphoma kinase (ALK)-targeted therapy is a promising strategy for the treatment of ALK-positive neuroblastoma (NB). Several ALK tyrosine kinase…”
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Abstract B49: Genome-wide analysis of liquid biopsies reveals a novel layer of tumorheterogeneity in neuroblastoma by Huetter, Sophia C., Walder, Diana S., Brunner, Clemens, Abbasi, Reza M., Rifatbegovic, Fikret, Hutter, Caroline, Ladenstein, Ruth, Ambros, Inge M., Ambros, Peter F.

“…Purpose: For 60% of high risk neuroblastoma patients this tumor is still a deadly disease. Even though great progress has been achieved over the last decades…”
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Bone marrows from neuroblastoma patients: An excellent source for tumor genome analyses by Abbasi, M. Reza, Rifatbegovic, Fikret, Brunner, Clemens, Ladenstein, Ruth, Ambros, Inge M., Ambros, Peter F.

“…Neuroblastoma is the most common extra-cranial solid tumor in childhood. Presence of disseminated tumor cells (DTCs) in the bone marrow (BM) at diagnosis and…”
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Novel Insights into Diagnosis, Biology and Treatment of Primary Diffuse Leptomeningeal Melanomatosis by Baumgartner, Alicia, Stepien, Natalia, Mayr, Lisa, Madlener, Sibylle, Dorfer, Christian, Schmook, Maria T, Traub-Weidinger, Tatjana, Lötsch-Gojo, Daniela, Kirchhofer, Dominik, Reisinger, Dominik, Hedrich, Cora, Arshad, Saleha, Irschik, Stefan, Boztug, Heidrun, Engstler, Gernot, Bernkopf, Marie, Rifatbegovic, Fikret, Höller, Christoph, Slavc, Irene, Berger, Walter, Müllauer, Leonhard, Haberler, Christine, Azizi, Amedeo A, Peyrl, Andreas, Gojo, Johannes

“…Primary diffuse leptomeningeal melanomatosis (PDLMM) is an extremely rare and aggressive cancer type for which best treatment strategies remain to be…”
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Abstract 977: Mapping bone marrow metastasis in neuroblastoma by deep multiplex imaging and transcriptomics by Lazic, Daria, Kromp, Florian, Rifatbegovic, Fikret, Repiscak, Peter, Mivalt, Filip, Halbritter, Florian, Bernkopf, Marie, Bileck, Andrea, Ussowicz, Marek, Ambros, Inge M., Ambros, Peter F., Gerner, Christopher, Ladenstein, Ruth, Ostalecki, Christian, Taschner-Mandl, Sabine

“…Introduction: Neuroblastoma is the most common solid tumor in infants and arises from progenitor cells during sympathoadrenal development. While the majority…”
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Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype: Deciphering the Repair Phenotype of Human Schwann Cells by Weiss, Tamara, Taschner-Mandl, Sabine, Bileck, Andrea, Slany, Astrid, Kromp, Florian, Rifatbegovic, Fikret, Frech, Christian, Windhager, Reinhard, Kitzinger, Hugo, Tzou, Chieh-Han, Ambros, Peter F., Gerner, Christopher, Ambros, Inge M.

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