Search Results - "Riezman, Isabelle"

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis by Berchtold, Doris, Piccolis, Manuele, Chiaruttini, Nicolas, Riezman, Isabelle, Riezman, Howard, Roux, Aurélien, Walther, Tobias C., Loewith, Robbie

“…The lipid content of the plasma membrane is dynamically regulated to maintain cellular homeostasis, but the molecular links between membrane stress and…”
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Lysophospholipids Facilitate COPII Vesicle Formation by Melero, Alejandro, Chiaruttini, Nicolas, Karashima, Takefumi, Riezman, Isabelle, Funato, Kouichi, Barlowe, Charles, Riezman, Howard, Roux, Aurélien

“…Coat protein complex II (COPII) proteins form vesicles from the endoplasmic reticulum to export cargo molecules to the Golgi apparatus. Among the many proteins…”
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Phosphatidylcholines from Pieris brassicae eggs activate an immune response in Arabidopsis by Stahl, Elia, Brillatz, Théo, Ferreira Queiroz, Emerson, Marcourt, Laurence, Schmiesing, André, Hilfiker, Olivier, Riezman, Isabelle, Riezman, Howard, Wolfender, Jean-Luc, Reymond, Philippe

“…Recognition of conserved microbial molecules activates immune responses in plants, a process termed pattern-triggered immunity (PTI). Similarly, insect eggs…”
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Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis by Girik, Vladimir, van Ek, Larissa, Dentand Quadri, Isabelle, Azam, Maral, Cruz Cobo, María, Mandavit, Marion, Riezman, Isabelle, Riezman, Howard, Gavin, Anne-Claude, Nunes-Hasler, Paula

“…Ceramides regulate phagocytosis; however, their exact function remains poorly understood. Here, we sought (1) to develop genetically encoded fluorescent tools…”
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Determination of the lipid composition of the GPI anchor by Aguilera-Romero, Auxiliadora, Sabido-Bozo, Susana, Lopez, Sergio, Cortes-Gomez, Alejandro, Rodriguez-Gallardo, Sofia, Perez-Linero, Ana Maria, Riezman, Isabelle, Riezman, Howard, Muñiz, Manuel

“…In eukaryotic cells, a subset of cell surface proteins is attached by the glycolipid glycosylphosphatidylinositol (GPI) to the external leaflet of the plasma…”
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Survival strategies of a sterol auxotroph by Carvalho, Maria, Schwudke, Dominik, Sampaio, Julio L, Palm, Wilhelm, Riezman, Isabelle, Dey, Gautam, Gupta, Gagan D, Mayor, Satyajit, Riezman, Howard, Shevchenko, Andrej, Kurzchalia, Teymuras V, Eaton, Suzanne

“…The high sterol concentration in eukaryotic cell membranes is thought to influence membrane properties such as permeability, fluidity and microdomain…”
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A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism by Savoglidis, Georgios, da Silveira dos Santos, Aline Xavier, Riezman, Isabelle, Angelino, Paolo, Riezman, Howard, Hatzimanikatis, Vassily

“…We present a model-based method, designated Inverse Metabolic Control Analysis (IMCA), which can be used in conjunction with classical Metabolic Control…”
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The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum by Cohen, Yifat, Megyeri, Márton, Chen, Oscar C W, Condomitti, Giuseppe, Riezman, Isabelle, Loizides-Mangold, Ursula, Abdul-Sada, Alaa, Rimon, Nitzan, Riezman, Howard, Platt, Frances M, Futerman, Anthony H, Schuldiner, Maya

“…The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins…”
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Yeast lipid analysis and quantification by mass spectrometry by Guan, Xue Li, Riezman, Isabelle, Wenk, Markus R, Riezman, Howard

“…The systematic and quantitative analysis of the different lipid species within a cell or an organism has recently become possible and the general approach has…”
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Two Pathways of Sphingolipid Biosynthesis Are Separated in the Yeast Pichia pastoris by Ternes, Philipp, Wobbe, Tobias, Schwarz, Marnie, Albrecht, Sandra, Feussner, Kirstin, Riezman, Isabelle, Cregg, James M., Heinz, Ernst, Riezman, Howard, Feussner, Ivo, Warnecke, Dirk

“…Although the yeast Saccharomyces cerevisiae has only one sphingolipid class with a head group based on phosphoinositol, the yeast Pichia pastoris as well as…”
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Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells by Epstein, Sharon, Kirkpatrick, Clare L., Castillon, Guillaume A., Muñiz, Manuel, Riezman, Isabelle, David, Fabrice P.A., Wollheim, Claes B., Riezman, Howard

“…Sphingolipids are not only important components of membranes but also have functions in protein trafficking and intracellular signaling. The LCB1 gene encodes…”
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Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans by Hannich, J. Thomas, Entchev, Eugeni V., Mende, Fanny, Boytchev, Hristio, Martin, René, Zagoriy, Vyacheslav, Theumer, Gabriele, Riezman, Isabelle, Riezman, Howard, Knölker, Hans-Joachim, Kurzchalia, Teymuras V.

“…In response to pheromone(s), Caenorhabditis elegans interrupts its reproductive life cycle and enters diapause as a stress-resistant dauer larva. This decision…”
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A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis by Lissina, Elena, Young, Brian, Urbanus, Malene L, Guan, Xue Li, Lowenson, Jonathan, Hoon, Shawn, Baryshnikova, Anastasia, Riezman, Isabelle, Michaut, Magali, Riezman, Howard, Cowen, Leah E, Wenk, Markus R, Clarke, Steven G, Giaever, Guri, Nislow, Corey

“…Using small molecule probes to understand gene function is an attractive approach that allows functional characterization of genes that are dispensable in…”
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A sensitive, expandable AQC-based LC-MS/MS method to measure amino metabolites and sphingolipids in cell and serum samples by Li, Xiaotian, Tian, Shuwei, Riezman, Isabelle, Qin, Yujiao, Riezman, Howard, Feng, Suihan

“…[Display omitted] •A robust reverse-phase HPLC-MS/MS method was proposed based on AQC derivatization.•This method is capable of separating and detecting…”
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Arf1 coordinates fatty acid metabolism and mitochondrial homeostasis by Enkler, Ludovic, Szentgyörgyi, Viktoria, Pennauer, Mirjam, Prescianotto-Baschong, Cristina, Riezman, Isabelle, Wiesyk, Aneta, Avraham, Reut Ester, Spiess, Martin, Zalckvar, Einat, Kucharczyk, Roza, Riezman, Howard, Spang, Anne

“…Lipid mobilization through fatty acid β-oxidation is a central process essential for energy production during nutrient shortage. In yeast, this catabolic…”
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Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES by Kawano, Shin, Tamura, Yasushi, Kojima, Rieko, Bala, Siqin, Asai, Eri, Michel, Agnès H, Kornmann, Benoît, Riezman, Isabelle, Riezman, Howard, Sakae, Yoshitake, Okamoto, Yuko, Endo, Toshiya

“…The endoplasmic reticulum (ER)-mitochondrial encounter structure (ERMES) physically links the membranes of the ER and mitochondria in yeast. Although the ER…”
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Subcellular Distribution of Cholesterol and Sphingolipids in Rat Hepatocytes by Stieger, Bruno, Steiger, Julia, Jiménez, Noemi, Riezman, Isabelle, Riezman, Howard

“…Hepatocytes are central in energy and lipid homeostasis of mammals and as such are key players in maintaining and regulating serum cholesterol levels. In…”
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Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network by Capasso, Serena, Sticco, Lucia, Rizzo, Riccardo, Pirozzi, Marinella, Russo, Domenico, Dathan, Nina A, Campelo, Felix, van Galen, Josse, Hölttä‐Vuori, Maarit, Turacchio, Gabriele, Hausser, Angelika, Malhotra, Vivek, Riezman, Isabelle, Riezman, Howard, Ikonen, Elina, Luberto, Chiara, Parashuraman, Seetharaman, Luini, Alberto, D'Angelo, Giovanni

“…Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre‐ and post‐Golgi…”
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mTORC2 Promotes Tumorigenesis via Lipid Synthesis by Guri, Yakir, Colombi, Marco, Dazert, Eva, Hindupur, Sravanth K., Roszik, Jason, Moes, Suzette, Jenoe, Paul, Heim, Markus H., Riezman, Isabelle, Riezman, Howard, Hall, Michael N.

“…Dysregulated mammalian target of rapamycin (mTOR) promotes cancer, but underlying mechanisms are poorly understood. We describe an mTOR-driven mouse model that…”
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Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis by da Silveira Dos Santos, Aline Xavier, Riezman, Isabelle, Aguilera-Romero, Maria-Auxiliadora, David, Fabrice, Piccolis, Manuele, Loewith, Robbie, Schaad, Olivier, Riezman, Howard

“…The regulatory pathways required to maintain eukaryotic lipid homeostasis are largely unknown. We developed a systematic approach to uncover new players in the…”
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