Search Results - "Rietschel, Th"

Gasteditorial des Präsidenten der Leibniz-Gemeinschaft, Prof. Ernst Th. Rietschel by Rietschel, Ernst Th

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A lethal role for lipid A in Salmonella infections by Khan, Shahid A., Everest, Paul, Servos, Spiros, Foxwell, Neale, Zähringer, Ulrich, Brade, Helmut, Rietschel, Ernst Th, Dougan, Gordon, Charles, Ian G., Maskell, Duncan J.

“…Salmonella infections in naturally susceptible mice grow rapidly, with death occurring only after bacterial numbers in vivo have reached a high threshold…”
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An infrared reflection-absorption spectroscopic (IRRAS) study of the interaction of lipid A and lipopolysaccharide Re with endotoxin-binding proteins by Kerth, Andreas, Garidel, Patrick, Howe, Jörg, Alexander, Christian, Mach, Jean-Pierre, Waelli, Thierry, Blume, Alfred, Th Rietschel, Ernst, Brandenburg, K

“…Lipopolysaccharides (LPS, endotoxins) are main constituents of the outer membranes of Gram-negative bacteria, with the 'endotoxic principle' lipid A anchoring…”
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Gasteditorial des Präsidenten der Leibniz-Gemeinschaft, Prof. Ernst Th. Rietschel by Rietschel, Ernst Th

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Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle by Howe, Jörg, Richter, Walter, Hawkins, Lynn, Rössle, Manfred, Alexander, Christian, Fournier, Karin, Mach, Jean Pierre, Waelli, Thierry, Gorczynski, Reginald M, Ulmer, Artur J, Brade, Helmut, Zamyatina, Alla, Kosma, Paul, Rietschel, Ernst Th, Brandenburg, Klaus

“…Although hemoglobin (Hb) is mainly present in the cytoplasm of erythrocytes (red blood cells), lower concentrations of pure, cell-free Hb are released…”
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Primary Structure of a New Phosphocholine-containing Glycoglycerolipid of Mycoplasma fermentans by Zähringer, Ulrich, Wagner, Frauke, Rietschel, Ernst Th, Ben-Menachem, Gil, Deutsch, Joseph, Rottem, Shlomo

“…The chemical structure of a novel phosphocholine-containing glycoglycerolipid, the major polar lipid in the cell membrane of Mycoplasma fermentans PG18, was…”
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The chemical structure of bacterial endotoxin in relation to bioactivity by Rietschel, E T, Kirikae, T, Schade, F U, Ulmer, A J, Holst, O, Brade, H, Schmidt, G, Mamat, U, Grimmecke, H D, Kusumoto, S

“…Lipopolysaccharides (LPS) constitute the O-antigens and endotoxins of Gram-negative bacteria. Whereas both the polysaccharide and lipid portion of LPS…”
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Mechanisms of Action of the Bactericidal/Permeability-Increasing Protein BPI on Endotoxin and Phospholipid Monolayers and Aggregates by Wiese, Andre, Brandenburg, Klaus, Lindner, Buko, Schromm, Andra B, Carroll, Stephen F, Rietschel, Ernst Th, Seydel, Ulrich

“…We have investigated the mechanisms of interaction of the recombinant N-terminal portion of bactericidal/permeability-increasing protein, rBPI21, with…”
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Components of gut bacteria as immunomodulators by Hamann, Lutz, EL-Samalouti, Volker, Ulmer, Artur J, Flad, Hans-Dieter, Rietschel, Ernst Th

“…In 1885 Louis Pasteur was the first to propose that the human immune system may be influenced by microorganisms. A large body of data has since been…”
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The biology of endotoxin by HEINE, H, RIETSCHEL, E. Th, ULMER, A. J

“…Endotoxin (lipopolysaccharide, LPS) is the major component of the outer leaflet of Gram-negative bacteria and has profound immunostimulatory and inflammatory…”
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Biochemistry and cell biology of bacterial endotoxins by Holst, Otto, Ulmer, Artur J., Brade, Helmut, Flad, Hans-Dieter, Rietschel, Ernst Th

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Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain by Khatri, Ismat, Alexander, C, Brandenburg, K, Fournier, K, Mach, J.P, Rietschel, E.Th, Ulmer, A.J, Terzioglu, E, Waelli, Th, Gorczynski, R.M

“…Abstract Previous studies showed a fetal sheep liver extract (FSLE), in association with monophosphoryl lipid A, MPLA (a bioactive component of lipid A of…”
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A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4 + Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection by Khatri, Ismat, Alexander, C., Brandenburg, K., Fournier, K., Lee, L., Mach, J.P., Rietschel, E.Th, Ulmer, A.J., Waelli, Th, Gorczynski, R.M.

“…Previous studies showed a fetal sheep liver extract (FSLE), in association with LPS, injected into aged (>20 months) mice reversed the altered polarization…”
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An alteration in the levels of populations of CD4+ Treg is in part responsible for altered cytokine production by cells of aged mice which follows injection with a fetal liver extract by Gorczynski, R.M, Alexander, C, Bessler, W, Brandenburg, K, Fournier, K, Mach, J.P, Mueller, S, Rietschel, E.Th, Ulmer, A.J, Waelli, Th, Zahringer, U, Khatri, I

“…Abstract We have shown previously that a fetal sheep liver extract (FSLE) containing significant quantities of fetal ovine gamma globin chain (Hbγ) and LPS…”
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NOS2‐derived nitric oxide regulates the size, quantity and quality of granuloma formation in Mycobacterium avium‐infected mice without affecting bacterial loads by Ehlers, S, Kutsch, S, Benini, J, Cooper, A, Hahn, C, Gerdes, J, Orme, I, Martin, C, Rietschel, E T

“…Granuloma formation in response to mycobacterial infections is associated with increased expression of inducible nitric oxide synthase (NOS2) within granuloma…”
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Influence of the supramolecular structure of free lipid A on its biological activity by BRANDENBURG, Klaus, MAYER, Hubert, KOCH, Michel H. J., WECKESSER, Jürgen, RIETSCHEL, Ernst Th, SEYDEL, Ulrich

“…The three‐dimensional supramolecular structures and the states of order of the acyl chains of lipid A from different Gram‐negative species were investigated at…”
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Synthesis of an analog of biosynthetic precursor Ia of lipid A by an improved method: a novel antagonist containing four ( S)-3-hydroxy fatty acids by Fukase, Koichi, Liu, Wen-Chi, Suda, Yasuo, Oikawa, Masato, Wada, Akira, Mori, Saeko, Ulmer, Arthur J., Rietschel, Ernst Th, Kusumoto, Shoichi

“…Synthesis of an analog of a biosynthetic precursor of lipid A containing four ( S)-3-hydroxytetradecanoic acids was effected via an improved synthetic route to…”
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Innate immune sensing and its roots: the story of endotoxin by Beutler, Bruce, Rietschel, Ernst Th

“…How does the host sense pathogens? Our present concepts grew directly from longstanding efforts to understand infectious disease: how microbes harm the host,…”
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The structure of the O‐specific chain of Legionella pneumophila serogroup 1 lipopolysaccharide by KNIREL, Yuriy A., RIETSCHEL, Ernst Th, MARRE, Reinhard, ZÄHRINGER, Ulrich

“…The O‐polysaccharide chain of Legionella pneumophila Philadelphia strain 1 (serogroup 1) lipopolysaccharide was investigated by means of 1H‐ and 13C‐NMR…”
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Analysis of interaction of cloned human and/or sheep fetal hemoglobin γ-chain and LPS in augmenting induction of inflammatory cytokine production in vivo and in vitro by Gorczynski, R.M., Alexander, C., Bessler, W., Fournier, K., Hoffmann, P., Mach, J.P., Rietschel, E. Th, Song, L., Waelli, Th, Westphal, O., Zahringer, U., Khatri, I.

“…We have reported earlier that purified preparations of sheep fetal hemoglobin, but not adult hemoglobin, in concert with non-stimulatory doses of…”
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