Search Results - "Rietschel, E T"

Innate immune sensing and its roots: the story of endotoxin by Beutler, Bruce, Rietschel, Ernst Th

“…How does the host sense pathogens? Our present concepts grew directly from longstanding efforts to understand infectious disease: how microbes harm the host,…”
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Tertiary Structure of Staphylococcus aureus Cell Wall Murein by Dmitriev, Boris A, Toukach, Filip V, Holst, O, Rietschel, E T, Ehlers, S

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Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis by Kos, O., Alexander, C., Brandenburg, K., Chen, Z., Heini, A., Heumann, D., Khatri, I., Mach, J.P., Rietschel, E.T., Tersikh, A., Ulmer, A.J., Waelli, T., Yu, K., Zähringer, U., Gorczynski, R.M.

“…We have shown that an altered tissue redox environment in mice lacking either murine beta Hemoglobin major (HgbβmaKO) or minor (HgbβmiKO) regulates…”
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Corrigendum to “An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression” [Int. Immunopharmacol. 50 (2017) 69–76] by Gorczynski, R.M., Alexander, C., Brandenburg, K., Chen, Z., Heini, A., Neumann, D., Mach, J.P., Rietschel, E.T., Terskikh, A., Ulmer, A.J., Yu, Kai, Zahringer, U., Khatri, I.

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An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression by Gorczynski, R.M., Alexander, C., Brandenburg, K., Chen, Z., Heini, A., Neumann, D., Mach, J.P., Rietschel, E.T., Tersikh, A., Ulmer, A.J., Yu, Kai, Zahringer, U., Khatri, I.

“…C5BL/6 female mice receiving dextran sodium sulfate in their drinking water develop an acute inflammatory colitis within 7d, with weight loss, histopathologic…”
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Corrigendum to “Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis” [Int. Immunopharmacol. 57 (2018) 112–120] by Kos, O., Alexander, C., Brandenburg, K., Chen, Z., Heini, A., Heumann, D., Khatri, I., Mach, J.P., Rietschel, E.T., Terskikh, A., Ulmer, A.J., Waelli, T., Yu, K., Zähringer, U., Gorczynski, R.M.

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Molecular mechanisms of endotoxin activity by SCHLETTER, J, HEINE, H, ULMER, A. J, RIETSCHEL, E. T

“…Endotoxin (lipopolysaccharide, LPS), a constituent of the outer membrane of the cell wall of gram-negative bacteria, exerts a wide variety of biological…”
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Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes by WEIDEMANN, B, SCHLETTER, J, DZIARSKI, R, KUSUMOTO, S, STELTER, F, RIETSCHEL, E. T, FLAD, H.-D, ULMER, A. J

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Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures by WEIDEMANN, B, BRADE, H, RIETSCHEL, E. T, DZIARSKI, R, BAZIL, V, KUSUMOTO, S, FLAD, H.-D, ULMER, A. J

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Bacterial endotoxin: molecular relationships of structure to activity and function by Rietschel, E T, Kirikae, T, Schade, F U, Mamat, U, Schmidt, G, Loppnow, H, Ulmer, A J, Zähringer, U, Seydel, U, Di Padova, F

“…Endotoxins of Gram-negative microbes fulfill as components of the outer membrane a vital function for bacterial viability and, if set free, induce in…”
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Fatal Granuloma Necrosis without Exacerbated Mycobacterial Growth in Tumor Necrosis Factor Receptor p55 Gene-Deficient Mice Intravenously Infected with Mycobacterium avium by EHLERS, S, BENINI, J, KUTSCH, S, ENDRES, R, RIETSCHEL, E. T, PFEFFER, K

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A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides by DI PADOVA, F. E, BRADE, H, RIETSCHEL, E. T, BARCLAY, G. R, POXTON, I. R, LIEHL, E, SCHUETZE, E, KOCHER, H. P, RAMSAY, G, SCHREIER, M. H, MCCLELLAND, D. B. L

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IL-1 induction-capacity of defined lipopolysaccharide partial structures by Loppnow, H, Brade, H, Durrbaum, I, Dinarello, CA, Kusumoto, S, Rietschel, ET, Flad, HD

“…Natural and synthetic lipid A as well as natural and synthetic oligosaccharide partial structures of LPS were examined in dose-response experiments to define…”
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Structural characterization of the lipid A component of pathogenic Neisseria meningitidis by Kulshin, V A, Zähringer, U, Lindner, B, Frasch, C E, Tsai, C M, Dmitriev, B A, Rietschel, E T

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The Internalization Time Course of a Given Lipopolysaccharide Chemotype Does Not Correspond to Its Activation Kinetics in Monocytes by LENTSCHAT, A, EL-SAMALOUTI, V. T, SCHLETTER, J, KUSUMOTO, I. S, BRADE, L, RIETSCHEL, E. T, GERDES, J, ERNST, M, FLAD, H.-D, ULMER, A. J

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Layered murein revisited : a fundamentally new concept of bacterial cell wall structure, biogenesis and function by DMITRIEV, B. A, EHLERS, S, RIETSCHEL, E. T

“…The classical concept of the architecture of microbial murein assumes cross-linked glycan chains to be arranged in horizontal layers outside of the plasma…”
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Molecular mechanics of the mycobacterial cell wall: From horizontal layers to vertical scaffolds by Dmitriev, Boris A., Ehlers, Stefan, Rietschel, Ernst T., Brennan, Patrick J.

“…Current models depicting the structural organization of the mycobacterial cell wall assume peptidoglycan and galactan strands to run in parallel to the…”
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Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A by KUHN, H. M, BRADE, L, APPEMELK, B. J, KUSUMOTO, S, RIETSCHEL, E. T, BRADE, H

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Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein by SCHLETTER, J, BRADE, H, BRADE, L, KRÜGER, C, LOPPNOW, H, KUSUMOTO, S, RIETSCHEL, E. T, FLAD, H.-D, ULMER, A. J

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A nonsubstituted primary hydroxyl group in position 6' of free lipid A is required for binding of lipid A monoclonal antibodies by BRADE, L, ENGEL, R, CHRIST, W. J, RIETSCHEL, E. T

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