Search Results - "Riesco Eizaguirre, Garcilaso"

Identification of an interactome network between lncRNAs and miRNAs in thyroid cancer reveals SPTY2D1-AS1 as a new tumor suppressor by Ramírez-Moya, Julia, Wert-Lamas, León, Acuña-Ruíz, Adrián, Fletcher, Alice, Wert-Carvajal, Carlos, McCabe, Christopher J., Santisteban, Pilar, Riesco-Eizaguirre, Garcilaso

“…Thyroid cancer is the most common primary endocrine malignancy in adults and its incidence is rapidly increasing. Long non-coding RNAs (lncRNAs), generally…”
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Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness by Ramírez-Moya, Julia, Wert-Lamas, León, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar

“…The global downregulation of microRNAs (miRNAs) is emerging as a common hallmark of cancer. However, the mechanisms underlying this phenomenon are not well…”
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A perspective view of sodium iodide symporter research and its clinical implications by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar

“…The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active iodide transport into the thyroid gland and into several…”
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Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer by Shen, Xiaopei, Zhu, Guangwu, Liu, Rengyun, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K, Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O'Neill, Christine J, Sywak, Mark S, Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Xing, Mingzhao

“…Purpose For the past 65 years, patient age at diagnosis has been widely used as a major mortality risk factor in the risk stratification of papillary thyroid…”
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The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis by Riesco-Eizaguirre, Garcilaso, Wert-Lamas, León, Perales-Patón, Javier, Sastre-Perona, Ana, Fernández, Lara P, Santisteban, Pilar

“…The presence of differentiated thyroid cells in thyroid cancer is critical for the antitumor response to radioactive iodide treatment, and loss of the…”
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BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer by Tao, Yubing, Wang, Fei, Shen, Xiaopei, Zhu, Guangwu, Liu, Rengyun, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K, Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O'Neill, Christine J, Sywak, Mark S, Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Zhao, Shihua, Wang, Yangang, Xing, Mingzhao

“…How lymph node metastasis (LNM)-associated mortality risk is affected by BRAF V600E in papillary thyroid cancer (PTC) remains undefined. To study whether BRAF…”
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The Prognostic Value of Tumor Multifocality in Clinical Outcomes of Papillary Thyroid Cancer by Wang, Fei, Yu, Xiaolong, Shen, Xiaopei, Zhu, Guangwu, Huang, Yueye, Liu, Rengyun, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K, Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O’Neill, Christine J, Sywak, Mark S, Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Wang, Yangang, Liu, Shiguo, Zhao, Jiajun, Zhao, Shihua, Xing, Mingzhao

“…Abstract Context Multifocality is often treated as a risk factor for papillary thyroid cancer (PTC), prompting aggressive treatments, but its prognostic value…”
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Hsa‐miR‐139‐5p is a prognostic thyroid cancer marker involved in HNRNPF‐mediated alternative splicing by Montero‐Conde, Cristina, Graña‐Castro, Osvaldo, Martín‐Serrano, Guillermo, Martínez‐Montes, Ángel M., Zarzuela, Eduardo, Muñoz, Javier, Torres‐Perez, Rafael, Pita, Guillermo, Cordero‐Barreal, Alfonso, Leandro‐García, Luis J., Letón, Rocío, López de Silanes, Isabel, Guadalix, Sonsoles, Pérez‐Barrios, Andrés, Hawkins, Federico, Guerrero‐Álvarez, Almudena, Álvarez‐Escolá, Cristina, Regojo‐Zapata, Rita M., Calsina, Bruna, Remacha, Laura, Roldán‐Romero, Juan M., Santos, María, Lanillos, Javier, Jordá, Mireia, Riesco‐Eizaguirre, Garcilaso, Zafon, Carles, González‐Neira, Anna, Blasco, Maria A., Al‐Shahrour, Fátima, Rodríguez‐Antona, Cristina, Cascón, Alberto, Robledo, Mercedes

“…It is critical to identify biomarkers and functional networks associated with aggressive thyroid cancer to anticipate disease progression and facilitate…”
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New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar

“…Well-differentiated thyroid cancer has in general terms a very good outcome. It has a very slow growth rate and, although it metastasises at a relatively high…”
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Validation of dynamic risk stratification and impact of BRAF in risk assessment of thyroid cancer, a nation-wide multicenter study by Pérez-Fernández, Laura, Sastre, Julia, Zafón, Carles, Oleaga, Amelia, Castelblanco, Esmeralda, Capel, Ismael, Galofré, Juan C, Guadalix-Iglesias, Sonsoles, De la Vieja, Antonio, Riesco-Eizaguirre, Garcilaso

“…The dynamic risk stratification (DRS) is a relatively new system in thyroid cancer that considers the response to primary treatment to improve the initial risk…”
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Rate of non-invasive follicular thyroid neoplasms with papillary-like nuclear features depends on pathologist’s criteria: a multicentre retrospective Southern European study with prolonged follow-up by Paja, Miguel, Zafón, Carles, Iglesias, Carmela, Ugalde, Aitziber, Cameselle-Teijeiro, Jose Manuel, Rodríguez-Carnero, Gemma, Fernández-Seara, Pilar, Anda, Emma, Povoa, Antónia, Quiceno, Hernán, Sánchez-Gómez, Nancy M., González, Clarisa, García-Pascual, Luis, Gómez de la Riva, Inés, Blanco, Concha, Meizoso, Telma, Riesco-Eizaguirre, Garcilaso, Capel, Ismael, Ortega, María Victoria, Mancha, Isabel, Chao, Montserrat, Alcázar, Victoria, Roselló, Esther, Maravall, Javier, López-Agulló, Susana, Pérez-Lázaro, Antonia, Meseguer, Pascual, Sanz, Javier, Paricio, Jose J., Echeverría, Saioa, Castaño, Ángel, Bella, Rosa M.

“…Purpose To determine the rate of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in a multi-institutional series from the…”
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NIS Mediates Iodide Uptake in the Female Reproductive Tract and Is a Poor Prognostic Factor in Ovarian Cancer by Riesco-Eizaguirre, Garcilaso, Leoni, Suzana Garcia, Mendiola, Marta, Estevez-Cebrero, Maria Angeles, Gallego, Marta Ines, Redondo, Andrés, Hardisson, David, Santisteban, Pilar, De la Vieja, Antonio

“…Context: The sodium iodide symporter (NIS) mediates active transport of iodide into the thyroid and the lactating mammary glands and is highly expressed in…”
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Solitary hemorrhagic cerebellar metastasis from occult papillary thyroid microcarcinoma by Lecumberri, Beatriz, Alvarez-Escolá, Cristina, Martín-Vaquero, Pilar, Nistal, Manuel, Martín, Virginia, Riesco-Eizaguirre, Garcilaso, Sosa, Grevelyn, Pallardo, Luis Felipe

“…Cerebellar metastasis (CM) from papillary thyroid carcinoma (PTC) is exceptional with only 12 reported cases and usually carries a very poor prognosis. In the…”
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The complex regulation of NIS expression and activity in thyroid and extrathyroidal tissues by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, De la Vieja, Antonio

“…The sodium/iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates active iodide transport into the thyroid gland and into several…”
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Radio-Iodide Treatment: From Molecular Aspects to the Clinical View by De la Vieja, Antonio, Riesco-Eizaguirre, Garcilaso

“…Thyroid radio-iodide therapy (RAI) is one of the oldest known and used targeted therapies. In thyroid cancer, it has been used for more than eight decades and…”
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ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar

“…Thyroid cancer is the most common endocrine malignancy giving rise to one of the most indolent solid cancers, but also one of the most lethal. In recent years,…”
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ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome by Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar

“…Thyroid cancer is the most common endocrine malignancy giving rise to one of the most indolent solid cancers, but also one of the most lethal. In recent years,…”
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The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer by Riesco-Eizaguirre, Garcilaso, Rodríguez, Irene, De la Vieja, Antonio, Costamagna, Eugenia, Carrasco, Nancy, Nistal, Manuel, Santisteban, Pilar

“…The activating mutation BRAF(V600E) is a frequent genetic event in papillary thyroid carcinomas (PTC) that predicts a poor prognosis, leading to loss of…”
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Association between BRAF V600E mutation and recurrence of papillary thyroid cancer by Xing, Mingzhao, Alzahrani, Ali S, Carson, Kathryn A, Shong, Young Kee, Kim, Tae Yong, Viola, David, Elisei, Rossella, Bendlová, Bela, Yip, Linwah, Mian, Caterina, Vianello, Federica, Tuttle, R Michael, Robenshtok, Eyal, Fagin, James A, Puxeddu, Efisio, Fugazzola, Laura, Czarniecka, Agnieszka, Jarzab, Barbara, O'Neill, Christine J, Sywak, Mark S, Lam, Alfred K, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, Nakayama, Hirotaka, Clifton-Bligh, Roderick, Tallini, Giovanni, Holt, Elizabeth H, Sýkorová, Vlasta

“…To investigate the prognostic value of BRAF V600E mutation for the recurrence of papillary thyroid cancer (PTC). This was a retrospective multicenter study of…”
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Association Between BRAF V600E Mutation and Mortality in Patients With Papillary Thyroid Cancer by Xing, Mingzhao, Alzahrani, Ali S, Carson, Kathryn A, Viola, David, Elisei, Rossella, Bendlova, Bela, Yip, Linwah, Mian, Caterina, Vianello, Federica, Tuttle, R. Michael, Robenshtok, Eyal, Fagin, James A, Puxeddu, Efisio, Fugazzola, Laura, Czarniecka, Agnieszka, Jarzab, Barbara, O’Neill, Christine J, Sywak, Mark S, Lam, Alfred K, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, Nakayama, Hirotaka, Tufano, Ralph P, Pai, Sara I, Zeiger, Martha A, Westra, William H, Clark, Douglas P, Clifton-Bligh, Roderick, Sidransky, David, Ladenson, Paul W, Sykorova, Vlasta

“…IMPORTANCE BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in PTC-related patient mortality has not been established…”
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