Search Results - "Riepe, M.W."
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Inhibition of hippocampal function in mild cognitive impairment: targeting the cholinergic hypothesis
Published in Neurobiology of aging (2006)“…Mild cognitive impairment (MCI) is a condition with an increased risk of developing Alzheimer's disease. Chief complaint and diagnostic criterion in subjects…”
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Spatial performance in a complex maze is associated with persistent long-term potentiation enhancement in mouse hippocampal slices at early training stages
Published in Neuroscience (29-06-2007)“…Abstract Long-term potentiation (LTP) and long-term depression (LTD) are principal reflections of synaptic plasticity that have been implicated in learning and…”
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Augmented Reality: Sustaining Autonomous Way-Finding in the Community for Older Persons with Cognitive Impairment
Published in The Journal of frailty & aging (2017)“…Impairment of autonomous way-finding subsequent to a multitude of neurodegenerative and other diseases impedes independence of older persons and their everyday…”
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Neurological and psychiatric practitioners' views on Alzheimer's disease and treatment thereof
Published in Dementia and geriatric cognitive disorders (01-12-2008)“…General views of practitioners shape medical routine. This study surveyed general views of neurological and psychiatric practitioners in Germany on Alzheimer's…”
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Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation
Published in Experimental neurology (01-10-2003)“…Repetitive inhibition of oxidative phosphorylation is an established model of neurodegeneration. In contrast, a single mild treatment can be…”
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An unbiased, staged, multicentre, validation strategy for Alzheimer's disease CSF tau levels
Published in Experimental neurology (01-06-2010)“…Newly proposed diagnostic criteria for Alzheimer's disease include cerebrospinal fluid (CSF) tau levels as one core supportive criterion. The published high…”
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[18F]FDG-PET in patients with Alzheimer's disease: marker of disease spread
Published in Dementia and geriatric cognitive disorders (2005)“…It is not known yet whether temporoparietal glucose hypometabolism in patients with probable Alzheimer's disease (AD) reflects disease severity or different…”
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Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease : Sex and Intelligence Matter
Published in International journal of alzheimer's disease (01-01-2009)“…Alzheimer's disease (AD) can be diagnosed according to new research criteria proposed recently (Dubois et al., 2007). Diagnosis is made on grounds of episodic…”
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Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice
Published in Mechanisms of ageing and development (01-02-2006)“…In the B6-Tg (ThylAPP)23Sdz (APP23tg) transgenic mouse model of Alzheimer's disease hypoxic tolerance is impaired prior to amyloid deposition. We therefore…”
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Impaired hypoxic tolerance and altered protein binding of NADH in presymptomatic APP23 transgenic mice
Published in Neuroscience (01-01-2002)“…It is being discussed whether impairment of energy metabolism is a final common pathway of neurodegeneration or initiates the neurodegenerative cascade. The…”
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Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus
Published in Neuroscience letters (29-07-2004)“…While one current focus for studying mechanisms of disease is investigation of transgenic mice confounding effects of the background strain often are…”
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Gender-dependent hypoxic tolerance mediated via gender-specific mechanisms
Published in Journal of neuroscience research (01-04-2002)“…Primary hypoxic tolerance and preconditioning are gender dependent and modulated in females during the estrus cycle. The underlying mechanisms, however, remain…”
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Mitochondrial Oxidation in Rat Hippocampus Can Be Preconditioned by Selective Chemical Inhibition of Succinic Dehydrogenase
Published in Experimental neurology (01-03-1996)“…Repeatedly it was reported that a short ischemic episode may ameliorate biochemical and morphological impairment upon succeeding severe ischemia. We…”
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Failure of neuronal ion exchange, not potentiated excitation, causes excitotoxicity after inhibition of oxidative phosphorylation
Published in Neuroscience (1995)“…Neuronal cell death during impaired energy metabolism is often attributed to increased activity at glutamate receptors, but this increase has not been directly…”
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