Search Results - "Riehm, Jan L."

Engineering of versatile redox partner fusions that support monooxygenase activity of functionally diverse cytochrome P450s by Bakkes, Patrick J., Riehm, Jan L., Sagadin, Tanja, Rühlmann, Ansgar, Schubert, Peter, Biemann, Stefan, Girhard, Marco, Hutter, Michael C., Bernhardt, Rita, Urlacher, Vlada B.

“…Most bacterial cytochrome P450 monooxygenases (P450s or CYPs) require two redox partner proteins for activity. To reduce complexity of the redox chain, the…”
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Engineering of CYP106A2 for steroid 9α- and 6β-hydroxylation by Nikolaus, Julia, Nguyen, Kim Thoa, Virus, Cornelia, Riehm, Jan L., Hutter, Michael, Bernhardt, Rita

“…CYP 106A2 from Bacillus megaterium ATCC 13368 has been described as a 15β-hydroxylase showing also minor 11α-, 9α- and 6β-hydroxylase activity for progesterone…”
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Binding modes of CYP106A2 redox partners determine differences in progesterone hydroxylation product patterns by Sagadin, Tanja, Riehm, Jan L., Milhim, Mohammed, Hutter, Michael C., Bernhardt, Rita

“…Natural redox partners of bacterial cytochrome P450s (P450s) are mostly unknown. Therefore, substrate conversions are performed with heterologous redox…”
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