Search Results - "Rieger, Angela C."
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A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration
Published in Journal of the American College of Cardiology (14-11-2017)“…The combination of autologous mesenchymal stem cells (MSCs) and cardiac stem cells (CSCs) synergistically reduces scar size and improves cardiac function in…”
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Clinical-based Cell Therapies for Heart Disease-Current and Future State
Published in Rambam Maimonides medical journal (29-04-2020)“…Patients have an ongoing unmet need for effective therapies that reverse the cellular and functional damage associated with heart damage and disease. The…”
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Comparison of Mesenchymal Stem Cell Efficacy in Ischemic Versus Nonischemic Dilated Cardiomyopathy
Published in Journal of the American Heart Association (17-07-2018)“…Ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) differ in histopathology and prognosis. Although transendocardial delivery of mesenchymal stem…”
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Genetic determinants of responsiveness to mesenchymal stem cell injections in non-ischemic dilated cardiomyopathy
Published in EBioMedicine (01-10-2019)“…Non-ischemic dilated cardiomyopathy (NIDCM) responds variably to intramyocardial injection of mesenchymal stem cells (MSCs). We hypothesized that NIDCM…”
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Non-oncologic incidental uptake on FAPI PET/CT imaging
Published in British journal of radiology (01-02-2023)“…Fibroblast-activation protein (FAP) is a serine protease classified in the dipeptidyl peptidase 4 (DPP4) family. FAP is predominantly expressed in activated…”
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Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy: POSEIDON-DCM Trial
Published in Journal of the American College of Cardiology (07-02-2017)“…Although human mesenchymal stem cells (hMSCs) have been tested in ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy…”
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Attenuation of frailty in older adults with mesenchymal stem cells
Published in Mechanisms of ageing and development (01-07-2019)“…•Frailty is a syndrome characterized by exhaustion, weight loss, a feeling of slowing down, and low levels of activity.•Frailty is associated with chronic…”
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Reply: Posterior Cingulate Involvement Does Not Argue Against LATE—And Who Said It Does?
Published in Journal of Nuclear Medicine (01-08-2022)Get full text
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Dose Comparison Study of Allogeneic Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy (The TRIDENT Study)
Published in Circulation research (10-11-2017)“…Cell dose and concentration play crucial roles in phenotypic responses to cell-based therapy for heart failure. To compare the safety and efficacy of 2 doses…”
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Is It Too Soon to Know When It's LATE?
Published in Journal of Nuclear Medicine (01-02-2022)Get full text
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The impact of patient sex on the response to intramyocardial mesenchymal stem cell administration in patients with non-ischaemic dilated cardiomyopathy
Published in Cardiovascular research (01-11-2020)“…Abstract Aims Sex differences impact the occurrence, presentation, prognosis, and response to therapy in heart disease. Particularly, the phenotypic…”
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Growth hormone-releasing hormone agonists ameliorate chronic kidney disease-induced heart failure with preserved ejection fraction
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2021)“…Therapies for heart failure with preserved ejection fraction (HFpEF) are lacking. Growth hormone-releasing hormone agonists (GHRH-As) have salutary effects in…”
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New insights into cell‐based therapy for heart failure from the CHART‐1 study
Published in European journal of heart failure (01-11-2017)Get full text
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Allogeneic Cell Combination Therapy Ameliorates Chronic Kidney Disease-Induced Heart Failure with Preserved Ejection Fraction
Published in Stem cells translational medicine (03-03-2022)“…Left ventricular hypertrophy and heart failure with preserved ejection fraction (HFpEF) are primary manifestations of the cardiorenal syndrome in patients with…”
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Abstract 35: Transendocardial Mesenchymal Stem Cell Injection Demonstrates Reverse Remodeling Effects of Global LV Volumes and Enhanced Lateral Papillary Muscle Shortening
Published in Circulation research (21-07-2017)“…Abstract only Rationale: Secondary mitral regurgitation (MR) carries a poor prognosis despite improvements in surgical and transcatheter interventions…”
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Abstract 16707: Human Embryonic Stem Cell-Derived Cardiomyocytes Are Safe and Improve Infarct Size and Cardiac Function in a Porcine Model of Myocardial Infarction
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionStem cell therapy is an emerging means of stimulating cardiac repair after myocardial infarction (MI). Human embryonic stem cell-derived…”
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Abstract 33: Combination of Allogeneic Mesenchymal and Kidney-derived Stem Cells Promotes Kidney Repair in a Swine Model of Chronic Kidney Disease
Published in Circulation research (21-07-2017)“…Abstract only Background: Chronic kidney disease (CKD) has a high prevalence (~14% of the population) and is associated with a significantly increased risk of…”
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Ischemic vs. Non-Ischemic Dilated Cardiomyopathy: a Comparative Study in Stem Cell Therapy Efficacy
Published in Journal of molecular and cellular cardiology (01-11-2017)Get full text
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