Search Results - "Riedl, Magdalena"

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement by Freeman, Spencer A., Vega, Anthony, Riedl, Magdalena, Collins, Richard F., Ostrowski, Phillip P., Woods, Elliot C., Bertozzi, Carolyn R., Tammi, Markku I., Lidke, Diane S., Johnson, Pauline, Mayor, Satyajit, Jaqaman, Khuloud, Grinstein, Sergio

“…Phagocytic receptors must diffuse laterally to become activated upon clustering by multivalent targets. Receptor diffusion, however, can be obstructed by…”
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An international consensus approach to the management of atypical hemolytic uremic syndrome in children by Loirat, Chantal, Fakhouri, Fadi, Ariceta, Gema, Besbas, Nesrin, Bitzan, Martin, Bjerre, Anna, Coppo, Rosanna, Emma, Francesco, Johnson, Sally, Karpman, Diana, Landau, Daniel, Langman, Craig B, Lapeyraque, Anne-Laure, Licht, Christoph, Nester, Carla, Pecoraro, Carmine, Riedl, Magdalena, van de Kar, Nicole C. A. J., Van de Walle, Johan, Vivarelli, Marina, Frémeaux-Bacchi, Véronique

“…Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the…”
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The Rise of Political Influencers—Perspectives on a Trend Towards Meaningful Content by Riedl, Magdalena, Schwemmer, Carsten, Ziewiecki, Sandra, Ross, Lisa M.

“…Despite an increasing information overflow in the era of digital communication, influencers manage to draw the attention of their followers with an authentic…”
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Vascular endothelial cells evade complement‐mediated membrane injury via Weibel‐Palade body mobilization by Riedl Khursigara, Magdalena, Schlam, Daniel, Noone, Damien G., Bruno, Valentina, Ortiz-Sandoval, Carolina G., Pluthero, Fred G., Kahr, Walter H. A., Bowman, Mackenzie L., James, Paula, Grinstein, Sergio, Licht, Christoph

“…Background Defective complement inhibition can lead to the formation of membrane attack complexes (MAC; C5b‐9) on the plasma membranes of vascular endothelial…”
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Early relapse rate determines further relapse risk: results of a 5-year follow-up study on pediatric CFH-Ab HUS by Hofer, Johannes, Riedl Khursigara, Magdalena, Perl, Markus, Giner, Thomas, Rosales, Alejandra, Cortina, Gerard, Waldegger, Siegfied, Jungraithmayr, Therese, Würzner, Reinhard

“…Background The complement factor H antibody (CFH-Ab)–associated hemolytic uremic syndrome (HUS) forms a distinct subgroup within the complement-mediated HUS…”
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Spectrum of complement-mediated thrombotic microangiopathies: pathogenetic insights identifying novel treatment approaches by Riedl, Magdalena, Fakhouri, Fadi, Le Quintrec, Moglie, Noone, Damien G, Jungraithmayr, Therese C, Fremeaux-Bacchi, Veronique, Licht, Christoph

“…Thrombotic microangiopathy (TMA) is a rare but severe disorder characterized by endothelial cell activation and thrombus formation. It manifests with the triad…”
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The role of von Willebrand factor in thrombotic microangiopathy by Noone, Damien G., Riedl, Magdalena, Licht, Christoph

“…Thrombotic microangiopathy (TMA) is caused by thrombus formation in the microvasculature. The disease spectrum of TMA includes, amongst others, thrombotic…”
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C3 Glomerulopathy and post-infectious glomerulonephritis define a disease spectrum by Al-Ghaithi, Badria, Chanchlani, Rahul, Riedl, Magdalena, Thorner, Paul, Licht, Christoph

“…Background Post-infectious glomerulonephritis (PIGN) usually follows a benign course, but few children have an atypical, severe presentation, and these…”
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An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome by Johnson, Sally, Stojanovic, Jelena, Ariceta, Gema, Bitzan, Martin, Besbas, Nesrin, Frieling, Michelle, Karpman, Diana, Landau, Daniel, Langman, Craig, Licht, Christoph, Pecoraro, Carmine, Riedl, Magdalena, Siomou, Ekaterini, van de Kar, Nicole, Walle, Johan Vande, Loirat, Chantal, Taylor, C. Mark

“…Background In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and…”
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Complement Factor H–Related Protein 1 Deficiency and Factor H Antibodies in Pediatric Patients with Atypical Hemolytic Uremic Syndrome by Hofer, Johannes, Janecke, Andreas R, Zimmerhackl, L B, Riedl, Magdalena, Rosales, Alejandra, Giner, Thomas, Cortina, Gerard, Haindl, Carola J, Petzelberger, Barbara, Pawlik, Miriam, Jeller, Verena, Vester, Udo, Gadner, Bettina, van Husen, Michael, Moritz, Michael L, Würzner, Reinhard, Jungraithmayr, Therese

“…This study evaluated the relevance of complement factor H (CFH)-related protein (CFHR) 1 deficiency in pediatric patients with atypical hemolytic uremic…”
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Utilizing therapeutic drug monitoring to optimize therapy with eculizumab and mycophenolate mofetil in a child with C3 glomerulonephritis by Riedl Khursigara, Magdalena, Chung, Erin, Tjon, James, Noone, Damien, Chami, Rose, Licht, Christoph, Teoh, Chia Wei

“…Background C3 glomerulonephritis (C3GN) can be a devastating disease with poor response to immunosuppressive therapy. Complement inhibition with eculizumab has…”
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Outcome 10 years after Shiga toxin-producing E. coli (STEC)-associated hemolytic uremic syndrome: importance of long-term follow-up by Rosales, Alejandra, Kuppelwieser, Sarah, Giner, Thomas, Hofer, Johannes, Riedl Khursigara, Magdalena, Orth-Höller, Dorothea, Borena, Wegene, Cortina, Gerard, Jungraithmayr, Therese, Würzner, Reinhard

“…Background Hemolytic uremic syndrome (HUS) is an important cause of acute kidney injury in children. HUS is known as an acute disease followed by complete…”
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Vaccination Status in Pediatric Solid-Organ Transplant Recipients and Their Household Members by Cortina, Gerard, Ojinaga, Violeta, Zlamy, Manuela, Giner, Thomas, Riedl, Magdalena, Rauchenzauner, Markus, Entenmann, Andreas, Müller, Thomas

“…Objectives: Vaccine-preventable diseases remain a major cause of morbidity and mortality in solid-organ transplant candidates and recipients. Newer recom -…”
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The alternative pathway of complement and the thrombotic microangiopathies by Teoh, Chia Wei, MB BCh BAO, MRCPI, Riedl, Magdalena, MD, PhD, Licht, Christoph, MD, FRCPC, FASN

“…Abstract Thrombotic microangiopathies (TMA) are disorders defined by microangiopathic hemolytic anemia, non-immune thrombocytopenia and have multi-organ…”
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Complement Activation Induces Neutrophil Adhesion and Neutrophil-Platelet Aggregate Formation on Vascular Endothelial Cells by Riedl, Magdalena, Noone, Damien G, Khan, Meraj A, Pluthero, Fred G, Kahr, Walter H A, Palaniyar, Nades, Licht, Christoph

“…Atypical hemolytic uremic syndrome is a thrombotic microangiopathy, which is linked to hereditary or autoimmune defects in complement activators or regulators…”
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Role of SGLT-2 Inhibitors in Ultrafiltration Failure in Peritoneal Dialysis: A Narrative Review by Riedl Khursigara, Magdalena, Liu, Ping, Kaur, Reetinder, Mavrakanas, Thomas A.

“…Purpose of review: Sodium-glucose co-transporter-2 (SGLT-2) inhibitors are glucose lowering agents with protective effects on cardiovascular health and the…”
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The loss of glycocalyx integrity impairs complement factor H binding and contributes to cyclosporine-induced endothelial cell injury by Teoh, Chia Wei, Riedl Khursigara, Magdalena, Ortiz-Sandoval, Carolina G, Park, Jee Woo, Li, Jun, Bohorquez-Hernandez, Arlette, Bruno, Valentina, Bowen, Emily E, Freeman, Spencer A, Robinson, Lisa A, Licht, Christoph

“…Calcineurin inhibitors (CNIs) are associated with nephrotoxicity, endothelial cell dysfunction, and thrombotic microangiopathy (TMA). Evolving evidence…”
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Vascular endothelial cells evade complement‐mediated membrane injury via Weibel‐Palade body mobilization by Riedl Khursigara, Magdalena, Schlam, Daniel, Noone, Damien G., Bruno, Valentina, Ortiz-Sandoval, Carolina G., Pluthero, Fred G., Kahr, Walter H.A., Bowman, Mackenzie L., James, Paula, Grinstein, Sergio, Licht, Christoph

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C3 Glomerulopathy by Riedl, Magdalena, Thorner, Paul, Licht, Christoph

“…Recent advances in our understanding of the disease pathology of membranoproliferative glomerulonephritis has resulted in its re-classification as complement…”
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A Guide for Adult Nephrologists and Hematologists to Managing Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy in Teens Transitioning to Young Adults by Riedl Khursigara, Magdalena, Matsuda-Abedini, Mina, Radhakrishnan, Seetha, Hladunewich, Michelle A, Lemaire, Mathieu, Teoh, Chia Wei, Noone, Damien, Licht, Christoph

“…Atypical hemolytic uremic syndrome and C3 glomerulopathy/immune complex membranoproliferative glomerulonephritis are ultra-rare chronic, complement-mediated…”
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