Search Results - "Riedl, Kenneth"
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Strawberry phytochemicals inhibit azoxymethane/dextran sodium sulfate-induced colorectal carcinogenesis in Crj: CD-1 mice
Published in Nutrients (10-03-2015)“…Human and experimental colon carcinogenesis are enhanced by a pro-inflammatory microenvironment. Pharmacologically driven chemopreventive agents and dietary…”
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High-Pressure Processing of Broccoli Sprouts: Influence on Bioactivation of Glucosinolates to Isothiocyanates
Published in Journal of agricultural and food chemistry (04-10-2017)“…Effects of high-pressure processing (HPP, 100–600 MPa for 3 min at 30 °C) on the glucosinolate content, conversion to isothiocyanates, and color changes during…”
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3
Dietary Black Raspberries Impact the Colonic Microbiome and Phytochemical Metabolites in Mice
Published in Molecular nutrition & food research (01-04-2019)“…Scope Black raspberries (BRB) are a rich source of bioactive phytochemicals, including anthocyanins and ellagitannins. These phytochemicals are poorly absorbed…”
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Substrate Specificity of Purified Recombinant Chicken β-Carotene 9′,10′-Oxygenase (BCO2)
Published in The Journal of biological chemistry (08-07-2016)“…Provitamin A carotenoids are oxidatively cleaved by β-carotene 15,15′-dioxygenase (BCO1) at the central 15-15′ double bond to form retinal (vitamin A…”
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Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)
Published in The Journal of biological chemistry (27-12-2013)“…Humans cannot synthesize vitamin A and thus must obtain it from their diet. β-Carotene 15,15′-oxygenase (BCO1) catalyzes the oxidative cleavage of provitamin A…”
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Modulation of the oral glucocorticoid system during black raspberry mediated oral cancer chemoprevention
Published in Carcinogenesis (New York) (11-02-2022)“…Abstract Recent reports suggest that glucocorticoids (GCs), which can be synthesized in the oral mucosa, play an important role in cancer development…”
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Uptake and metabolism of β-apo-8′-carotenal, β-apo-10′-carotenal, and β-apo-13-carotenone in Caco-2 cells
Published in Journal of lipid research (01-06-2019)“…β-Apocarotenoids are eccentric cleavage products of carotenoids formed by chemical and enzymatic oxidations. They occur in foods containing carotenoids and…”
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Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms
Published in PLoS pathogens (01-10-2020)“…People with HIV (PWH) are at increased risk for atherosclerotic cardiovascular disease (ASCVD). Proportions of vascular homing monocytes are enriched in PWH;…”
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Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified sulforaphane
Published in Molecular nutrition & food research (01-10-2014)“…SCOPE: Broccoli sprouts are a rich source of glucosinolates, a group of phytochemicals that when hydrolyzed, are associated with cancer prevention. Our…”
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The Human Enzyme That Converts Dietary Provitamin A Carotenoids to Vitamin A Is a Dioxygenase
Published in The Journal of biological chemistry (09-05-2014)“…β-Carotene 15–15′-oxygenase (BCO1) catalyzes the oxidative cleavage of dietary provitamin A carotenoids to retinal (vitamin A aldehyde). Aldehydes readily…”
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Optimization of extraction methods for quantification of microcystin-LR and microcystin-RR in fish, vegetable, and soil matrices using UPLC–MS/MS
Published in Harmful algae (01-06-2018)“…•Methods were developed to maximize recovery of microcystin (MC) in samples with complex tissue matrices, using UPLC-MS/MS.•MC recovery rates varied with…”
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Lipidome Alterations with Exercise Among People With and Without HIV: An Exploratory Study
Published in AIDS research and human retroviruses (01-07-2022)“…Age-related comorbidities and physical function impairments in aging people with HIV (PWH) can be improved through exercise interventions. The mechanisms…”
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Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: Characterization, metabolism, and interconversion
Published in Molecular nutrition & food research (01-11-2012)“…Scope Epidemiologic evidence suggests diets rich in cruciferous vegetables, particularly broccoli, are associated with lower bladder cancer risk. Our…”
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Compartmental and noncompartmental modeling of ¹³C-lycopene absorption, isomerization, and distribution kinetics in healthy adults
Published in The American journal of clinical nutrition (01-12-2015)“…Lycopene, which is a red carotenoid in tomatoes, has been hypothesized to mediate disease-preventive effects associated with tomato consumption. Lycopene is…”
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Phenolic profile, in vitro antimicrobial activity and antioxidant capacity of Vaccinium meridionale Swartz pomace
Published in Heliyon (01-05-2020)“…Berries of Vaccinium meridionale Swartz contain a variety of phytochemicals, which are believed to account for their bioactive properties. The potential of…”
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Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults
Published in The Journal of nutrition (01-04-2012)“…The proposed health-promoting effects of the pericarp from mangosteen fruit have been attributed to a family of polyphenols referred to as xanthones. The…”
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Chromatographic separation of PTAD-derivatized 25-hydroxyvitamin D3 and its C-3 epimer from human serum and murine skin
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-06-2015)“…•We demonstrate HPLC separation of PTAD-derivatized 25OHD3 and its C-3 epimer.•Both analytes were detected in serum and skin at nM and pmol/g levels,…”
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Characterization of Black Raspberry Functional Food Products for Cancer Prevention Human Clinical Trials
Published in Journal of agricultural and food chemistry (07-05-2014)“…Our team is designing and fully characterizing black raspberry (BRB) food products suitable for long-term cancer prevention studies. The processing, scale-up,…”
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Altered Lipidome Composition Is Related to Markers of Monocyte and Immune Activation in Antiretroviral Therapy Treated Human Immunodeficiency Virus (HIV) Infection and in Uninfected Persons
Published in Frontiers in immunology (16-04-2019)“…HIV infection and antiretroviral therapy (ART) have both been linked to dyslipidemia and increased cardiovascular disease (CVD) risk. Alterations in the…”
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Efficacy comparison of lyophilised black raspberries and combination of celecoxib and PBIT in prevention of carcinogen-induced oesophageal cancer in rats
Published in Journal of functional foods (01-12-2016)“…•Black raspberries are more effective than drug combination in cancer prevention.•Black raspberries could inhibit activation of NFκB, MAPK and AKT.•Black…”
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