Search Results - "Riederer, Peter"
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Monoamine oxidase-B inhibitors in the treatment of Parkinson’s disease: clinical–pharmacological aspects
Published in Journal of Neural Transmission (01-11-2018)“…This invited narrative review emphasizes the role of MAO-B inhibition in the drug portfolio for dopamine substitution in patients with Parkinson’s disease…”
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Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression
Published in Journal of Neural Transmission (01-02-2016)“…Monoamine oxidase types A and B (MAO-A, MAO-B) regulate the levels of monoamine neurotransmitters in the brain, and their dysfunction may be involved in the…”
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3
The Nigral Coup in Parkinson's Disease by α-Synuclein and Its Associated Rebels
Published in Cells (Basel, Switzerland) (09-03-2021)“…The risk of Parkinson's disease increases with age. However, the etiology of the illness remains obscure. It appears highly likely that the neurodegenerative…”
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4
Botulinum toxin’s axonal transport from periphery to the spinal cord
Published in Neurochemistry international (01-07-2012)“…Occurrence of cleaved SNAP-25 in ipsilateral lumbal ventral horn following botulinum toxin A (30U/kg) subcutaneous injection into the rat hind paw. [Display…”
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Pharmacological aspects of the neuroprotective effects of irreversible MAO-B inhibitors, selegiline and rasagiline, in Parkinson’s disease
Published in Journal of Neural Transmission (01-11-2018)“…The era of MAO-B inhibitors dates back more than 50 years. It began with Kálmán Magyar’s outstanding discovery of the selective inhibitor, selegiline. This…”
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6
The relevance of iron in the pathogenesis of Parkinson’s disease
Published in Journal of neurochemistry (01-09-2011)“…J. Neurochem. (2011) 118, 939–957. Alterations of iron levels in the brain has been observed and documented in a number of neurodegenerative disorders…”
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New Aspects Regarding the Fluorescence Spectra of Melanin and Neuromelanin in Pigmented Human Tissue Concerning Hypoxia
Published in International journal of molecular sciences (01-08-2024)“…Melanin is a crucial pigment in melanomagenesis. Its fluorescence in human tissue is exceedingly weak but can be detected through advanced laser spectroscopy…”
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Perspective: Treatment for Disease Modification in Chronic Neurodegeneration
Published in Cells (Basel, Switzerland) (12-04-2021)“…Symptomatic treatments are available for Parkinson's disease and Alzheimer's disease. An unmet need is cure or disease modification. This review discusses…”
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TDM in psychiatry and neurology: A comprehensive summary of the consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology, update 2017; a tool for clinicians
Published in The world journal of biological psychiatry (03-04-2018)“…Objectives: Therapeutic drug monitoring (TDM) combines the quantification of drug concentrations in blood, pharmacological interpretation and treatment…”
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Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics
Published in The world journal of biological psychiatry (03-07-2016)“…Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that are specific to certain disorders or syndromes. The objective of…”
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Introduction to the special issue on monoamine oxidase A and B: eternally enigmatic isoenzymes
Published in Journal of Neural Transmission (01-11-2018)Get full text
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12
Safety of Cerebrolysin for Neurorecovery after Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Twelve Randomized-Controlled Trials
Published in Pharmaceuticals (Basel, Switzerland) (13-12-2021)“…We performed a systematic search and meta-analysis of available literature to determine the safety profile of Cerebrolysin in acute ischemic stroke, filling…”
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Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer’s disease: a long-term follow up study
Published in Journal of Neural Transmission (01-05-2011)“…Cerebral amyloid angiopathy is manifested as accumulation of amyloid β (Aβ) peptide in the wall of meningeal and cerebral arteries, arterioles and capillaries…”
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Postencephalitic Parkinsonism: Unique Pathological and Clinical Features-Preliminary Data
Published in Cells (Basel, Switzerland) (10-09-2024)“…Postencephalitic parkinsonism (PEP) is suggested to show a virus-induced pathology, which is different from classical idiopathic Parkinson's disease (PD) as…”
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Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability
Published in Neurobiology of disease (01-12-2008)“…Abstract Increasing evidence has linked inflammatory processes to neurodegenerative disorders, including Alzheimer's and Parkinson's disease (PD). Tumor…”
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From attention-deficit hyperactivity disorder to sporadic Alzheimer's disease-Wnt/mTOR pathways hypothesis
Published in Frontiers in neuroscience (16-02-2023)“…Alzheimer's disease (AD) is the most common neurodegenerative disorder with the majority of patients classified as sporadic AD (sAD), in which etiopathogenesis…”
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Aldehyde dehydrogenase (ALDH) in Alzheimer’s and Parkinson’s disease
Published in Journal of Neural Transmission (01-02-2016)Get full text
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Streptozotocin Impairs Proliferation and Differentiation of Adult Hippocampal Neural Stem Cells in Vitro -Correlation With Alterations in the Expression of Proteins Associated With the Insulin System
Published in Frontiers in aging neuroscience (18-05-2018)“…Rats intracerebroventricularily (icv) treated with streptozotocin (STZ), shown to generate an insulin resistant brain state, were used as an animal model for…”
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Chronic monoamine oxidase-B inhibitor treatment blocks monoamine oxidase-A enzyme activity
Published in Journal of Neural Transmission (01-04-2014)“…Patients with Parkinson’s disease receive selective irreversible monoamine oxidase (MAO)-B inhibitors, but their effects on MAO-A activity are not known during…”
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Lewy Bodies: A Spectator or Salient Killer?
Published in CNS & neurological disorders drug targets (01-01-2015)“…Lewy bodies (LBs) are characteristic hallmarks of Parkinson's disease (PD). However, their role in the pathology of PD is not established yet. Are they primary…”
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