Search Results - "Rieckmann, K.H"
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Steady-state kinetics of proguanil and its active metabolite, cycloguanil, in man
Published in Chemotherapy (Basel) (1988)“…The pharmacokinetics of proguanil and its active metabolite, cycloguanil, were determined at steady-state in 6 healthy male volunteers after daily…”
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The activity of pyrimethamine and sulphadoxine against Plasmodium falciparum determined by the in vitro microtechnique
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (1983)“…The reported increase of infections of Plasmodium falciparum which are no longer susceptible to a combination of pyrimethamine and…”
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A rabbit--in vitro system to evaluate drug action against Plasmodium falciparum
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (1983)“…A rabbit-in vitro model system is described which can determine the activity of anti-malarial drugs against erythrocytic stages of Plasmodium falciparum. Serum…”
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Gender differences in gastrointestinal disturbances and plasma concentrations of tafenoquine in healthy volunteers after tafenoquine administration for post-exposure vivax malaria prophylaxis
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-03-2007)“…In an open-label sequential cohort study, we compared gastrointestinal (GI) disturbances and plasma tafenoquine concentrations after administration of…”
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Immunochromatographic test for malaria diagnosis
Published in The Lancet (British edition) (01-06-1996)Get more information
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Comparison of bioassay and high performance liquid chromatographic assay of artesunate and dihydroartemisinin in plasma
Published in Acta tropica (01-08-2003)“…The study was a comparison of bioassay and HPLC analysis of artesunate (ARTS) and dihydroartemisinin (DHA) in plasma. ARTS and DHA in plasma samples from…”
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Antimalarial activity of the triple combination of proguanil, atovaquone and dapsone
Published in Acta tropica (30-09-1997)“…The combination of proguanil and atovaquone has been shown to be more effective in curing drug-resistant infections of falciparum malaria than atovaquone or…”
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Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitro
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-07-1996)“…Clinical studies have shown proguanil ( prog) combined with atovaquone ( atq) to be an effective and safe antimalarial combination for the treatment of…”
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Ex vivo antimalarial activity of proguanil combined with dapsone against cycloguanil-resistant Plasmodium falciparum isolates
Published in Acta tropica (10-09-1997)“…The ex vivo antimalarial activity of plasma samples obtained from 20 healthy Caucasian volunteers following daily proguanil (200 mg) plus dapsone (8 mg) for…”
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Efficacy of amodiaquine against a chloroquine-resistant strain of Plasmodium vivax
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-07-1990)Get more information
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Pharmacokinetics of halofantrine and n-desbutylhalofantrine in patients with falciparum malaria following a multiple dose regimen of halofantrine
Published in European journal of clinical pharmacology (01-01-1991)“…Halofantrine is a new blood schizontocidal drug used for the treatment of multidrug-resistant falciparum malaria. The pharmacokinetics of halofantrine (HAL)…”
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Falciparum Malaria: The Urgent Need for Safe and Effective Drugs
Published in Annual review of medicine (01-01-1983)“…Plasmodium falciparum, review of methods developed to monitor drug resistance and susceptibility, alternatives to chloroquine for treatment and prophylaxis,…”
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Multiple-dose kinetics in healthy volunteers and in vitro antimalarial activity of proguanil plus dapsone
Published in Chemotherapy (Basel) (1990)“…The multiple-dose kinetics of a daily dose of proguanil (200 mg) coadministered with dapsone (10 mg) was investigated in 6 healthy adult male volunteers. The…”
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Synergistic antimalarial activity of dapsone/dihydrofolate reductase inhibitors and the interaction of antifol, antipyrimidine and antipurine combinations against Plasmodium falciparum in vitro
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (1987)“…Using low folate, low p-aminobenzoic acid medium, 2 isolates of Plasmodium falciparum were tested in vitro against a wide range of antimetabolite compounds…”
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Plasmodium falciparum: isolation and purification of spontaneously released merozoites by nylon membrane sieves
Published in Experimental parasitology (01-01-1982)Get more information
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Isolation of intracellular parasites (Plasmodium falciparum) from culture using free-flow electrophoresis: Separation of the free parasites according to stages
Published in The Journal of parasitology (01-06-1982)“…Plasmodium falciparum, isolation of intracellular parasites from culture using free-flow electrophoresis, separation of free parasites according to stages…”
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