Search Results - "Rieckmann, Jan"
-
1
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
Published in Cell (20-10-2016)“…Metabolic activity is intimately linked to T cell fate and function. Using high-resolution mass spectrometry, we generated dynamic metabolome and proteome…”
Get full text
Journal Article -
2
Social network architecture of human immune cells unveiled by quantitative proteomics
Published in Nature immunology (01-05-2017)“…Immune cells give rise to the most interconnected system in the body. Meissner and colleagues perform comprehensive proteomics and secretomics to describe in…”
Get full text
Journal Article -
3
Dynamics in protein translation sustaining T cell preparedness
Published in Nature immunology (01-08-2020)“…In response to pathogenic threats, naive T cells rapidly transition from a quiescent to an activated state, yet the underlying mechanisms are incompletely…”
Get full text
Journal Article -
4
Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed
Published in Nature biotechnology (01-08-2018)“…Interactions between hundreds of immune cells and cytokines in disease are mined from PubMed. Cytokines are signaling molecules secreted and sensed by immune…”
Get full text
Journal Article -
5
Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
Published in Cell reports (Cambridge) (09-03-2021)“…A major pathway for proinflammatory protein release by macrophages is inflammasome-mediated pyroptotic cell death. As conventional secretion, unconventional…”
Get full text
Journal Article -
6
Functional classification of memory CD8+ T cells by CX3CR1 expression
Published in Nature communications (25-09-2015)“…Localization of memory CD8 + T cells to lymphoid or peripheral tissues is believed to correlate with proliferative capacity or effector function. Here we…”
Get full text
Journal Article