Search Results - "Riddell, S."

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo by Sommermeyer, D, Hudecek, M, Kosasih, P L, Gogishvili, T, Maloney, D G, Turtle, C J, Riddell, S R

“…Adoptive T-cell therapy with gene-modified T cells expressing a tumor-reactive T-cell receptor or chimeric antigen receptor (CAR) is a rapidly growing field of…”
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Circuit dissection of the role of somatostatin in itch and pain by Huang, Jing, Polgár, Erika, Solinski, Hans Jürgen, Mishra, Santosh K., Tseng, Pang-Yen, Iwagaki, Noboru, Boyle, Kieran A., Dickie, Allen C., Kriegbaum, Mette C., Wildner, Hendrik, Zeilhofer, Hanns Ulrich, Watanabe, Masahiko, Riddell, John S., Todd, Andrew J., Hoon, Mark A.

“…Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which…”
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Fully human CD19-specific chimeric antigen receptors for T-cell therapy by Sommermeyer, D, Hill, T, Shamah, S M, Salter, A I, Chen, Y, Mohler, K M, Riddell, S R

“…Impressive results have been achieved by adoptively transferring T-cells expressing CD19-specific CARs with binding domains from murine mAbs to treat B-cell…”
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CD19-Targeted chimeric antigen receptor-modified T-cell immunotherapy for B-cell malignancies by Turtle, CJ, Riddell, SR, Maloney, DG

“…Chimeric antigen receptors (CARs) comprise a tumor‐targeting moiety, often in the form of a single chain variable fragment derived from a monoclonal antibody,…”
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Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion by Fiorenza, S., Zheng, Y., Purushe, J., Bock, T. J., Sarthy, J., Janssens, D. H., Sheih, A. S., Kimble, E. L., Kirchmeier, D., Phi, T. D., Gauthier, J., Hirayama, A. V., Riddell, S. R., Wu, Q., Gottardo, R., Maloney, D. G., Yang, J. Y. H., Henikoff, S., Turtle, C. J.

“…Chimeric antigen receptor-modified T cell (CAR-T) immunotherapy has revolutionised blood cancer treatment. Parsing the genetic underpinnings of T cell quality…”
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Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn by Dickie, Allen C., Bell, Andrew M., Iwagaki, Noboru, Polgár, Erika, Gutierrez-Mecinas, Maria, Kelly, Rosalind, Lyon, Heather, Turnbull, Kirsten, West, Steven J., Etlin, Alexander, Braz, Joao, Watanabe, Masahiko, Bennett, David L.H., Basbaum, Allan I., Riddell, John S., Todd, Andrew J.

“…Excitatory interneurons account for the majority of neurons in the superficial dorsal horn, but despite their presumed contribution to pain and itch, there is…”
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Populations of inhibitory and excitatory interneurons in lamina II of the adult rat spinal dorsal horn revealed by a combined electrophysiological and anatomical approach by Yasaka, Toshiharu, Tiong, Sheena Y.X., Hughes, David I., Riddell, John S., Todd, Andrew J.

“…Lamina II contains a large number of interneurons involved in modulation and transmission of somatosensory (including nociceptive) information. However, its…”
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Adoptive T Cell Therapy Using Antigen-Specific CD8+T Cell Clones for the Treatment of Patients with Metastatic Melanoma: In vivo Persistence, Migration, and Antitumor Effect of Transferred T Cells by Yee, C., Thompson, J. A., Byrd, D., Riddell, S. R., Roche, P., Celis, E., Greenberg, P. D.

“…Adoptive T cell therapy, involving the ex vivo selection and expansion of antigen-specific T cell clones, provides a means of augmenting antigen-specific…”
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Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling by Boyle, Kieran A, Polgar, Erika, Gutierrez-Mecinas, Maria, Dickie, Allen C, Cooper, Andrew H, Bell, Andrew M, Jumolea, Evelline, Casas-Benito, Adrian, Watanabe, Masahiko, Hughes, David I, Weir, Gregory A, Riddell, John S, Todd, Andrew J

“…Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that…”
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Olfactory mucosa for transplant-mediated repair: A complex tissue for a complex injury? by Lindsay, Susan L., Riddell, John S., Barnett, Susan C.

“…Damage to the brain and spinal cord leads to permanent functional disability because of the very limited capacity of the central nervous system (CNS) for…”
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Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits by Gadalla, Kamal K E, Ross, Paul D, Riddell, John S, Bailey, Mark E S, Cobb, Stuart R

“…Rett syndrome (RTT) is a genetic disorder characterized by a range of features including cognitive impairment, gait abnormalities and a reduction in purposeful…”
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A combined electrophysiological and morphological study of neuropeptide Y–expressing inhibitory interneurons in the spinal dorsal horn of the mouse by Iwagaki, Noboru, Ganley, Robert P., Dickie, Allen C., Polgár, Erika, Hughes, David I., Del Rio, Patricia, Revina, Yulia, Watanabe, Masahiko, Todd, Andrew J., Riddell, John S.

“…The spinal dorsal horn contains numerous inhibitory interneurons that control transmission of somatosensory information. Although these cells have important…”
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Identification of Nonepithelial Multipotent Cells in the Embryonic Olfactory Mucosa by Tomé, Mercedes, Lindsay, Susan L., Riddell, John S., Barnett, Susan C.

“…Olfactory mucosal (OM) tissue, a potential source of stem cells, is currently being assessed in the clinic as a candidate tissue for transplant‐mediated repair…”
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An Outbreak of Multidrug-Resistant Acinetobacter baumannii-calcoaceticus Complex Infection in the US Military Health Care System Associated with Military Operations in Iraq by Scott, Paul, Deye, Gregory, Srinivasan, Arjun, Murray, Clinton, Moran, Kimberly, Hulten, Ed, Fishbain, Joel, Craft, David, Riddell, Scott, Lindler, Luther, Mancuso, James, Milstrey, Eric, Bautista, Christian T., Patel, Jean, Ewell, Alessa, Hamilton, Tacita, Gaddy, Charla, Tenney, Martin, Christopher, George, Petersen, Kyle, Endy, Timothy, Petruccelli, Bruno

“…Background. We investigated an outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection among US service members injured in…”
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Hydrological response in a savanna hillslope under different rainfall regimes by Van Tol, Johan, Julich, Stefan, Bouwer, Darren, Riddell, Edward S

“…Soil water is a link between precipitation and the functioning of ecological systems. It is therefore critical to understand exactly how soil water regimes are…”
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Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain by Polgár, E, Hughes, D.I, Riddell, J.S, Maxwell, D.J, Puskár, Z, Todd, A.J

“…GABA and glycine are inhibitory neurotransmitters used by many neurons in the spinal dorsal horn, and intrathecal administration of GABA A and glycine receptor…”
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Lack of evidence for significant neuronal loss in laminae I–III of the spinal dorsal horn of the rat in the chronic constriction injury model by Polgár, E., Gray, S., Riddell, J.S., Todd, A.J.

“…Peripheral nerve injury leads to structural and functional changes in the spinal dorsal horn, and these are thought to be involved in the development of…”
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Groundwater-surface water interactions in an ephemeral savanna catchment, Kruger National Park by Lorentz, Simon, Riddell, Edward S, Nel, Jaco, Van Tol, Johan, Fundisi, Daniel, Jumbi, Faith, van Niekerk, Ashton

“…The semi-arid conditions in savanna landscapes ensure that ephemeral drainage dominates the hydrological network in these dryland systems. Quantification of…”
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Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats by Barnett, Susan C., Riddell, John S.

“…One of the main research strategies to improve treatment for spinal cord injury involves the use of cell transplantation. This review looks at the advantages…”
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International e-Delphi survey to define best practice in the reporting of intracranial pressure monitoring recording data by Kommer, Maya, Hawthorne, Christopher, Moss, Laura, Piper, Ian, O'Kane, Roddy, Czosnyka, Marek, Enblad, Per, Hemphill, J Claude, Spiegelberg, Andreas, Riddell, John S., Shaw, Martin

“…Intracranial pressure (ICP) monitoring is a very commonly performed neurosurgical procedure but there is a wide variation in how it is reported, hindering…”
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