Search Results - "Riddell, Kylie"

Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial by Ali, Arwa, Dumbrava, Monica, Riddell, Kylie, Stewart, Nina, Ward, Robyn, Ibrahim, Ahmed K, Chin, Melvin

“…Planar-based measurements of lesions in metastatic melanoma have limitations in estimating tumor burden of a patient and in predicting response to treatment…”
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Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial by Bardsley, George, Daley-Yates, Peter, Baines, Amanda, Kempsford, Rodger, Williams, Mathew, Mallon, Tony, Braithwaite, Irene, Riddell, Kylie, Joshi, Shashidhar, Bareille, Philippe, Beasley, Richard, Fingleton, James

“…Fluticasone furoate/Vilanterol trifenatate (FF/VI) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration…”
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Pharmacokinetics of Salbutamol Delivered from the Unit Dose Dry Powder Inhaler: Comparison with the Metered Dose Inhaler and Diskus Dry Powder Inhaler by Moore, Alison, Riddell, Kylie, Joshi, Shashidhar, Chan, Robert, Mehta, Rashmi

“…To compare the systemic exposure of salbutamol following delivery from the unit dose dry powder inhaler (UD-DPI) system with that from the Diskus and metered…”
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An Adaptive Physiologically Based Pharmacokinetic–Driven Design to Investigate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Molibresib (GSK525762) in Healthy Female Volunteers by Riddell, Kylie, Patel, Aarti, Collins, Gary, Zhou, Yanyan, Schramek, Dan, Kremer, Brandon E., Ferron‐Brady, Geraldine

“…Molibresib (GSK525762), an orally bioavailable small molecule with 2 major equipotent active metabolites, is being developed for the treatment of cancers…”
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Pharmacokinetic Comparison of a Unit Dose Dry Powder Inhaler with a Multidose Dry Powder Inhaler for Delivery of Fluticasone Furoate by Mehta, Rashmi, Moore, Alison, Riddell, Kylie, Joshi, Shashidhar, Chan, Robert

“…The unit dose dry powder inhaler (UD-DPI) is being considered as an alternative inhaler platform that, if developed, has the potential to improve access to…”
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An Innovative Approach to Characterize Clinical ADME and Pharmacokinetics of the Inhaled Drug Nemiralisib Using an Intravenous Microtracer Combined with an Inhaled Dose and an Oral Radiolabel Dose in Healthy Male Subjects by Harrell, Andrew W, Wilson, Robert, Man, Yau Lun, Riddell, Kylie, Jarvis, Emily, Young, Graeme, Chambers, Robert, Crossman, Lee, Georgiou, Alex, Pereira, Adrian, Kenworthy, David, Beaumont, Claire, Marotti, Miriam, Wilkes, Denisa, Hessel, Edith M, Fahy, William A

“…An innovative open-label, crossover clinical study was used to investigate the excretion balance, pharmacokinetics, and metabolism of nemiralisib-an inhaled…”
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Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations by Patel, Aarti, Wilson, Robert, Harrell, Andrew W, Taskar, Kunal S, Taylor, Maxine, Tracey, Helen, Riddell, Kylie, Georgiou, Alex, Cahn, Anthony P, Marotti, Miriam, Hessel, Edith M

“…In vitro data for low-dose inhaled phosphoinositide 3-kinase delta inhibitor nemiralisib revealed that it was a substrate and a potent metabolism-dependent…”
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Open-Label, Randomized, 6-Way Crossover, Single-Dose Study to Determine the Pharmacokinetics of Batefenterol (GSK961081) and Fluticasone Furoate When Administered Alone or in Combination by Ambery, Claire, Riddell, Kylie, Daley-Yates, Peter

“…To investigate the pharmacokinetics of inhaled batefenterol (BAT) and fluticasone furoate (FF) given alone or in combination via ELLIPTA® dry powder inhaler…”
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Comparison of the Pharmacokinetics of Salmeterol and Fluticasone Propionate 50/100 [mu]g Delivered in Combination as a Dry Powder Via a Capsule-Based Inhaler and a Multi-Dose Inhaler by Mehta, Rashmi, Riddell, Kylie, Gupta, Ashutosh, Louey, Margaret D, Chan, Robert H

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Comparison of the Pharmacokinetics of Salmeterol and Fluticasone Propionate 50/100 µg Delivered in Combination as a Dry Powder Via a Capsule-Based Inhaler and a Multi-Dose Inhaler by Mehta, Rashmi, Riddell, Kylie, Gupta, Ashutosh, Louey, Margaret D, Chan, Robert H.

“…Background and Objectives The Rotacaps ® /Rotahaler ® system is a single unit dose inhaler being developed to deliver inhaled salmeterol/fluticasone propionate…”
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