Search Results - "Rickett, Natasha Y"

Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease by Dong, Xiaofeng, Munoz-Basagoiti, Jordana, Rickett, Natasha Y, Pollakis, Georgios, Paxton, William A, Günther, Stephan, Kerber, Romy, Ng, Lisa F P, Elmore, Michael J, Magassouba, N'faly, Carroll, Miles W, Matthews, David A, Hiscox, Julian A

“…Viral load is a major contributor to outcome in patients with Ebola virus disease (EVD), with high values leading to a fatal outcome. Evidence from the…”
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High Resolution Analysis of Respiratory Syncytial Virus Infection In Vivo by Aljabr, Waleed, Armstrong, Stuart, Rickett, Natasha Y., Pollakis, Georgios, Touzelet, Olivier, Cloutman-Green, Elaine, Matthews, David A., Hiscox, Julian A.

“…Human respiratory syncytial virus (HRSV) is a major cause of pediatric infection and also causes disease in the elderly and those with underlying respiratory…”
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Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care by Bosworth, Andrew, Rickett, Natasha Y, Dong, Xiaofeng, Ng, Lisa F P, García-Dorival, Isabel, Matthews, David A, Fletcher, Tom, Jacobs, Michael, Thomson, Emma C, Carroll, Miles W, Hiscox, Julian A

“…Ebola virus disease (EVD) is an often-fatal infection where the effectiveness of medical countermeasures is uncertain. During the West African outbreak…”
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Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity by Lum, Fok-Moon, Lee, David, Chua, Tze-Kwang, Tan, Jeslin J L, Lee, Cheryl Y P, Liu, Xuan, Fang, Yongxiang, Lee, Bernett, Yee, Wearn-Xin, Rickett, Natasha Y, Chia, Po-Ying, Lim, Vanessa, Leo, Yee-Sin, Matthews, David A, Hiscox, Julian A, Ng, Lisa F P

“…Zika virus (ZIKV) has reemerged in the population and caused unprecedented global outbreaks. Here, the transcriptomic consequences of ZIKV infection were…”
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Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus by Liu, Xuan, Speranza, Emily, Muñoz-Fontela, César, Haldenby, Sam, Rickett, Natasha Y, Garcia-Dorival, Isabel, Fang, Yongxiang, Hall, Yper, Zekeng, Elsa-Gayle, Lüdtke, Anja, Xia, Dong, Kerber, Romy, Krumkamp, Ralf, Duraffour, Sophie, Sissoko, Daouda, Kenny, John, Rockliffe, Nichola, Williamson, E Diane, Laws, Thomas R, N'Faly, Magassouba, Matthews, David A, Günther, Stephan, Cossins, Andrew R, Sprecher, Armand, Connor, John H, Carroll, Miles W, Hiscox, Julian A

“…In 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely…”
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Vaccination to Reduce Antimicrobial Resistance Burden—Data Gaps and Future Research by Tadesse, Birkneh Tilahun, Keddy, Karen H, Rickett, Natasha Y, Zhusupbekova, Aidai, Poudyal, Nimesh, Lawley, Trevor, Osman, Majdi, Dougan, Gordon, Kim, Jerome H, Lee, Jung-Seok, Jeon, Hyon Jin, Marks, Florian

“…Abstract Antimicrobial resistance (AMR) poses an immediate danger to global health. If unaddressed, the current upsurge in AMR threatens to reverse the…”
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TREM-1 activation is a potential key regulator in driving severe pathogenesis of enterovirus A71 infection by Amrun, Siti Naqiah, Tan, Jeslin J. L., Rickett, Natasha Y., Cox, Jonathan A., Lee, Bernett, Griffiths, Michael J., Solomon, Tom, Perera, David, Ooi, Mong How, Hiscox, Julian A., Ng, Lisa F. P.

“…Hand, foot and mouth disease (HFMD), caused by enterovirus A71 (EV-A71), presents mild to severe disease, and sometimes fatal neurological and respiratory…”
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A comparison of host gene expression signatures associated with infection in vitro by the Makona and Ecran (Mayinga) variants of Ebola virus by Bosworth, Andrew, Dowall, Stuart D., Garcia-Dorival, Isabel, Rickett, Natasha Y., Bruce, Christine B., Matthews, David A., Fang, Yongxiang, Aljabr, Waleed, Kenny, John, Nelson, Charlotte, Laws, Thomas R., Williamson, E. Diane, Stewart, James P., Carroll, Miles W., Hewson, Roger, Hiscox, Julian A.

“…The Ebola virus (EBOV) variant Makona (which emerged in 2013) was the causative agent of the largest outbreak of Ebola Virus Disease recorded. Differences in…”
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Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS by Aljabr, Waleed, Alruwaili, Muhannad, Penrice-Randal, Rebekah, Alrezaihi, Abdulrahman, Harrison, Abbie Jasmine, Ryan, Yan, Bentley, Eleanor, Jones, Benjamin, Alhatlani, Bader Y, AlShahrani, Dayel, Mahmood, Zana, Rickett, Natasha Y, Alosaimi, Bandar, Naeem, Asif, Alamri, Saad, Alsran, Hadel, Hamed, Maaweya E, Dong, Xiaofeng, Assiri, Abdullah M, Alrasheed, Abdullah R, Hamza, Muaawia, Carroll, Miles W, Gemmell, Matthew, Darby, Alistair, Donovan-Banfield, I’ah, Stewart, James P, Matthews, David A, Davidson, Andrew D, Hiscox, Julian A

“…Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic infection that emerged in the Middle East in 2012. Symptoms range from mild to severe and…”
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Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut by Carroll, Miles W, Haldenby, Sam, Rickett, Natasha Y, Pályi, Bernadett, Garcia-Dorival, Isabel, Liu, Xuan, Barker, Gary, Bore, Joseph Akoi, Koundouno, Fara Raymond, Williamson, E Diane, Laws, Thomas R, Kerber, Romy, Sissoko, Daouda, Magyar, Nóra, Di Caro, Antonino, Biava, Mirella, Fletcher, Tom E, Sprecher, Armand, Ng, Lisa F P, Rénia, Laurent, Magassouba, N'faly, Günther, Stephan, Wölfel, Roman, Stoecker, Kilian, Matthews, David A, Hiscox, Julian A

“…In this study, samples from the 2013-2016 West African Ebola virus outbreak from patients in Guinea with Ebola virus disease (EVD) were analyzed to discover…”
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Determinants of Patient Survival following Acute Ebola Virus Infection by Rickett, Natasha Y

“…The 2013–2016 outbreak of Zaire ebolavirus (EBOV) in West Africa was unprecedented in scale and has sparked a great deal of interest into the pathogen. EBOV is…”
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