Search Results - "Rickards, Carole"

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112 by Prod'homme, Virginie, Sugrue, Daniel M, Stanton, Richard J, Nomoto, Akio, Davies, James, Rickards, Carole R, Cochrane, Daniel, Moore, Melanie, Wilkinson, Gavin W G, Tomasec, Peter

“…Human cytomegalovirus (HCMV) UL141 induces protection against natural killer cell-mediated cytolysis by downregulating cell surface expression of CD155…”
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Modulation of natural killer cells by human cytomegalovirus by Wilkinson, Gavin W.G, Tomasec, Peter, Stanton, Richard J, Armstrong, Melanie, Prod’homme, Virginie, Aicheler, Rebecca, McSharry, Brian P, Rickards, Carole R, Cochrane, Daniel, Llewellyn-Lacey, Sian, Wang, Eddie C.Y, Griffin, Cora A, Davison, Andrew J

“…Abstract Human cytomegalovirus (HCMV) causes lifelong, persistent infections and its survival is under intense, continuous selective pressure from the immune…”
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The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1- NK Cells by Prod'homme, Virginie, Griffin, Cora, Aicheler, Rebecca J, Wang, Eddie C. Y, McSharry, Brian P, Rickards, Carole R, Stanton, Richard J, Borysiewicz, Leszek K, Lopez-Botet, Miguel, Wilkinson, Gavin W. G, Tomasec, Peter

“…The inhibitory leukocyte Ig-like receptor 1 (LIR-1, also known as ILT2, CD85j, or LILRB1) was identified by its high affinity for the human CMV (HCMV) MHC…”
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Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141 by Wilkinson, Gavin W G, Tomasec, Peter, Wang, Eddie C Y, Davison, Andrew J, Vojtesek, Borivoj, Armstrong, Melanie, Griffin, Cora, McSharry, Brian P, Morris, Rebecca J, Llewellyn-Lacey, Sian, Rickards, Carole, Nomoto, Akio, Sinzger, Christian

“…Natural killer (NK) cells are crucial in the control of cytomegalovirus infections in mice and humans. Here we show that the viral UL141 gene product has an…”
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Surface Expression of HLA-E, An Inhibitor of Natural Killer Cells, Enhanced by Human Cytomegalovirus gpUL40 by Tomasec, Peter, Braud, Veronique M., Rickards, Carole, Powell, Martin B., McSharry, Brian P., Gadola, Stephan, Cerundolo, Vincenzo, Borysiewicz, Leszek K., McMichael, Andrew J., Gavin W. G. Wilkinson

“…The nonclassical major histocompatibility complex (MHC) class I molecule HLA-E inhibits natural killer (NK) cell-mediated lysis by interacting with CD94/NKG2A…”
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Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product by Wilkinson, GW, Kelly, C, Sinclair, JH, Rickards, C

“…GW Wilkinson, C Kelly, JH Sinclair and C Rickards Department of Medicine, University of Wales College of Medicine, Cardiff, UK. WMDGWW@CARDIFF.AC.UK The PML…”
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The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1 super(+) but Activates LIR-1 super(-) NK Cells by Prod'homme, Virginie, Griffin, Cora, Aicheler, Rebecca J, Wang, Eddie CY, McSharry, Brian P, Rickards, Carole R, Stanton, Richard J, Borysiewicz, Leszek K, Lopez-Botet, Miguel, Wilkinson, Gavin WG, Tomasec, Peter

“…The inhibitory leukocyte Ig-like receptor 1 (LIR-1, also known as ILT2, CD85j, or LILRB1) was identified by its high affinity for the human CMV (HCMV) MHC…”
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The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1− NK Cells1 by Prod’homme, Virginie, Griffin, Cora, Aicheler, Rebecca J., Wang, Eddie C. Y., McSharry, Brian P., Rickards, Carole R., Stanton, Richard J., Borysiewicz, Leszek K., López-Botet, Miguel, Wilkinson, Gavin W. G., Tomasec, Peter

“…The inhibitory leukocyte Ig-like receptor 1 (LIR-1, also known as ILT2, CD85j, or LILRB1) was identified by its high affinity for the human CMV (HCMV) MHC…”
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Suface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40 by Tomasec, Peter, Braud, Veronique V, Rickards, Carole, Powell, Martin B

“…The nonclassical major histocompatibility complex (MHC) class I molecule HLA-E inhibits natural killer (NK) cell-mediated lysis by interacting with CD94/NKG2A…”
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Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18 by Griffin, Cora, Wang, Eddie C. Y, McSharry, Brian P, Rickards, Carole, Browne, Helena, Wilkinson, Gavin W. G, Tomasec, Peter

“…1 Section of Infection and Immunity, Cardiff University, Tenovus Building, Heath Park, Cardiff CF14 4XX, UK 2 Division of Virology, Department of Pathology,…”
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Prolonged exposure to N-methyl-D-aspartate increases intracellular and secreted somatostatin in rat cortical cells by Ham, J, Rickards, C, Scanlon, M

“…Somatostatin (SRIF) release from fetal rat cortical cells was stimulated by exposure to 10(-5) M N-methyl-D-aspartate (NMDA) (250 +/- 20% of basal at 96 h). A…”
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Glutamate neurotoxicity: a role for non-N-methyl-D-aspartate receptors? by Duberley, R M, Rickards, C R, Ham, J, Scanlon, M F

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Photo-affinity labelling of the thyrotropin receptor by Buckland, Paul R., Rickards, Carole R., Howells, Rogers D., Jones, Eirian Davies, Smith, Bernard Rees

“…The thyrotropin (TSH) receptor was analyzed by affinity labelling. Detergent solubilised porcine and human TSH receptors have been partially purified by…”
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Role of excitatory amino acids on somatostatin production in the central nervous system by Rickards, C, Ham, J, Fitzgerald, R, Scanlon, M F

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Differential responses of rat cerebral somatostatinergic and cholinergic cells to glutamate agonists by HAM, J, DUBERLEY, R, RICKARDS, C, SCANLON, M. F

“…Reductions in cortical somatostatin (SRIH) and choline acetyl-transferase (ChAT) are major biochemical deficits in Alzheimer disease (AD). SRIH and ChAT were…”
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The interaction of graves' IgG with the thyrotrophin receptor by Rickards, Carole, Buckland, Paul, Rees Smith, Bernard, Hall, Reginald

“…Sera from patients with Graves' disease contain antibodies which inhibit the binding of thyrotrophin (TSH) to thyroid membranes. Investigations demonstrate…”
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A structure for the porcine TSH receptor by Kajita, Yoshihiro, Rickards, Carole R., Buckland, Paul R., Howells, Roger D., Smith, Bernard Rees

“…Affinity purified, detergent-solubilised porcine TSH receptors have been crosslinked to a 125I-labelled photoactive derivative of TSH and analysed by gel…”
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Plasma lipid analysis by thin-layer chromatography with flame ionisation detection and quantitation by Bradley, D M, Rickards, C R, Thomas, N S

“…A method is presented whereby cholesterol, cholesterol ester, triacylglycerol, non-esterified fatty acid and polar lipid in plasma may be simultaneously…”
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Immunoprecipitation of TSH-TSH receptor complexes by Parkes, A B, Kajita, Y, Buckland, P R, Howells, R D, Rickards, C R, Creagh, F M, Rees Smith, B

“…The ability of Graves' sera to interact with the TSH receptor crosslinked to a 125I-labelled photoactive derivative of TSH has been investigated. Crosslinked…”
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