Search Results - "Rick, M"

Regulation of immunity and allergy by helminth parasites by Maizels, Rick M.

“…There is increasing interest in helminth parasite modulation of the immune system, both from the fundamental perspective of the “arms race” between host and…”
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Regulation of the host immune system by helminth parasites by Maizels, Rick M., PhD, McSorley, Henry J., PhD

“…Helminth parasite infections are associated with a battery of immunomodulatory mechanisms that affect all facets of the host immune response to ensure their…”
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Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities by Candelario-Jalil, Eduardo, Dijkhuizen, Rick M., Magnus, Tim

“…Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central nervous system. Structurally comprising the BBB, brain…”
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Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules by Maizels, Rick M., Smits, Hermelijn H., McSorley, Henry J.

“…Helminths are extraordinarily successful parasites due to their ability to modulate the host immune response. They have evolved a spectrum of immunomodulatory…”
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Functional morphology of the blood–brain barrier in health and disease by Liebner, Stefan, Dijkhuizen, Rick M., Reiss, Yvonne, Plate, Karl H., Agalliu, Dritan, Constantin, Gabriela

“…The adult quiescent blood–brain barrier (BBB), a structure organised by endothelial cells through interactions with pericytes, astrocytes, neurons and…”
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Helminth Infections and Host Immune Regulation by MCSORLEY, Henry J, MAIZELS, Rick M

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Helminth extracellular vesicles: Interactions with the host immune system by Drurey, Claire, Maizels, Rick M.

“…•Helminth EV release, a new paradigm in host-parasite interactions.•EV cargo of immune modulators.•Heterogeneity of EVs in source and targets.•EVs modulate the…”
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Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections by Coakley, Gillian, Maizels, Rick M, Buck, Amy H

“…Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring information between cells and organisms across all three kingdoms of life…”
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Understanding artemisinin-resistant malaria: what a difference a year makes by Fairhurst, Rick M

“…PURPOSE OF REVIEWThe emergence of artemisinin resistance in Southeast Asia (SEA), where artemisinin combination therapies (ACTs) are beginning to fail,…”
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Toxocara canis: Molecular basis of immune recognition and evasion by Maizels, Rick M.

“…Toxocara canis has extraordinary abilities to survive for many years in the tissues of diverse vertebrate species, as well as to develop to maturity in the…”
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Extracellular vesicles: new targets for vaccines against helminth parasites by Drurey, Claire, Coakley, Gillian, Maizels, Rick M.

“…[Display omitted] •Current vaccine candidates against helminth infection have shown limited success.•Helminths release extracellular vesicles (EVs) which act…”
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Ascarosides from helminths pack a punch against allergy by Maizels, Rick M

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Diversity and dialogue in immunity to helminths by Maizels, Rick M, Allen, Judith E

“…Key Points Infection with large metazoan parasites (helminths) typically induces a type 2 immune response. Redundancy within the immune system, as well as…”
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Identifying novel candidates and configurations for human helminth vaccines by Maizels, Rick M

“…: Human infections with helminth worm parasites are extraordinarily prevalent across tropical and subtropical parts of the world, and control relies primarily…”
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Immunomodulation by helminth parasites: Defining mechanisms and mediators by McSorley, Henry J., Hewitson, James P., Maizels, Rick M.

“…[Display omitted] ► Parasite products contain immunomodulatory molecules. ► These products can suppress disease in multiple rodent models of immunopathology. ►…”
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Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis by Taylor, Steve M, Dr, Parobek, Christian M, BS, Fairhurst, Rick M, MD

“…Summary Background Haemoglobinopathies can reduce the risk of malaria syndromes. We aimed to quantify the relation between different haemoglobin mutations and…”
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Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites by Gerbe, François, Sidot, Emmanuelle, Smyth, Danielle J., Ohmoto, Makoto, Matsumoto, Ichiro, Dardalhon, Valérie, Cesses, Pierre, Garnier, Laure, Pouzolles, Marie, Brulin, Bénédicte, Bruschi, Marco, Harcus, Yvonne, Zimmermann, Valérie S., Taylor, Naomi, Maizels, Rick M., Jay, Philippe

“…Epithelial tuft cells secretion of IL-25 is shown to regulate type 2 epithelial responses to helminth parasite infection via an IL-13/IL-4Rα-dependent feedback…”
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Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity by Hewitson, James P., Grainger, John R., Maizels, Rick M.

“…Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a Th2-dominated immune response, but stimulation of…”
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Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies by Witkowski, Benoit, PhD, Amaratunga, Chanaki, PhD, Khim, Nimol, MSc, Sreng, Sokunthea, Chim, Pheaktra, Kim, Saorin, Lim, Pharath, MD, Mao, Sivanna, MD, Sopha, Chantha, MD, Sam, Baramey, MD, Anderson, Jennifer M, PhD, Duong, Socheat, Prof, Chuor, Char Meng, MD, Taylor, Walter R J, MD, Suon, Seila, MD, Mercereau-Puijalon, Odile, PhD, Fairhurst, Rick M, Dr, Menard, Didier, Dr

“…Summary Background Artemisinin resistance in Plasmodium falciparum lengthens parasite clearance half-life during artemisinin monotherapy or artemisinin-based…”
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Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study by Amato, Roberto, Pearson, Richard D, Almagro-Garcia, Jacob, Amaratunga, Chanaki, Lim, Pharath, Suon, Seila, Sreng, Sokunthea, Drury, Eleanor, Stalker, Jim, Miotto, Olivo, Fairhurst, Rick M, Kwiatkowski, Dominic P

“…Antimalarial resistance is rapidly spreading across parts of southeast Asia where dihydroartemisinin–piperaquine is used as first-line treatment for Plasmodium…”
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