Search Results - "Richtmann, Sarah"
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Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes
Published in Cells (Basel, Switzerland) (28-05-2024)“…Bladder cancer is a heterogenous disease, and molecular subtyping is a promising method to capture this variability. Currently, the immune compartment in…”
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Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients?
Published in Pulmonary circulation (01-04-2023)“…Iron deficiency is common in idiopathic and heritable pulmonary arterial hypertension patients (I/HPAH). A previous report suggested a dysregulation of the…”
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The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer
Published in Translational research : the journal of laboratory and clinical medicine (01-10-2024)“…Lung cancer has been shown to be targetable by novel immunotherapies which reactivate the immune system and enable tumor cell killing. However, treatment…”
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FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC
Published in Cancers (11-05-2019)“…Although targeted therapy has improved the survival rates in the last decade, non-small-cell lung cancer (NSCLC) is still the most common cause of…”
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Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma
Published in International journal of oncology (01-04-2022)“…Transmembrane serine protease 2 (TMPRSS2) has been intensively investigated during the current Sars-CoV-2 pandemic as a virus activating protease. Furthermore,…”
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Clinical Significance of SERPINA1 Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC
Published in Cancers (04-09-2019)“…High expression of gene encoding acute phase protein, alpha1-antitrypsin (AAT), is associated with various tumors. We sought to examine the significance of and…”
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Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and ISREBF1/I Gene
Published in Cancers (01-09-2022)“…The accumulation of lipid droplets (LDs) and the high expression of genes involved in LD formation, such as SREBF1 (sterol regulatory element binding…”
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Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis
Published in Cancers (26-11-2020)“…(IRX) encodes members of homeodomain containing genes which are involved in development and differentiation. Since it has been reported that the gene is…”
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Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene
Published in Cancers (14-09-2022)“…To explore the relationship between cancer cell SREBF1 expression, lipid droplets (LDs) formation, and the sensitivity to chemotherapies, we cultured lung…”
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10
Reduction of BMPR2 mRNA Expression in Peripheral Blood of Pulmonary Arterial Hypertension Patients: A Marker for Disease Severity?
Published in Genes (26-04-2022)“…Pulmonary arterial hypertension (PAH) can be caused by pathogenic variants in the gene bone morphogenetic protein receptor 2 (BMPR2). While BMPR2 protein…”
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