Search Results - "Richter, Helene"

The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing by Alexander, Rebecca, Aragón, Oriana R., Bookwala, Jamila, Cherbuin, Nicolas, Gatt, Justine M., Kahrilas, Ian J., Kästner, Niklas, Lawrence, Alistair, Lowe, Leroy, Morrison, Robert G., Mueller, Sven C., Nusslock, Robin, Papadelis, Christos, Polnaszek, Kelly L., Helene Richter, S., Silton, Rebecca L., Styliadis, Charis

“…•Neurophysiological correlates of positive emotions contribute to wellbeing.•Brain networks that implement positive emotions are flexible and…”
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It is time for an empirically informed paradigm shift in animal research by Richter, S. Helene, von Kortzfleisch, Vanessa

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Systematic heterogenization for better reproducibility in animal experimentation by Richter, S Helene

“…The scientific literature is full of articles discussing poor reproducibility of findings from animal experiments as well as failures to translate results from…”
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Beyond Standardization: Improving External Validity and Reproducibility in Experimental Evolution by Desjardins, Eric, Kurtz, Joachim, Kranke, Nina, Lindeza, Ana, Richter, S Helene

“…Abstract Discussions of reproducibility are casting doubts on the credibility of experimental outcomes in the life sciences. Although experimental evolution is…”
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Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning by Haaker, Jan, Maren, Stephen, Andreatta, Marta, Merz, Christian J., Richter, Jan, Richter, S. Helene, Meir Drexler, Shira, Lange, Maren D., Jüngling, Kay, Nees, Frauke, Seidenbecher, Thomas, Fullana, Miquel A., Wotjak, Carsten T., Lonsdorf, Tina B.

“…•Considers methodological comparability of translational research in fear conditioning in rodents and humans.•Equips researchers with practical and…”
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Brain serotonin deficiency affects female aggression by Kästner, Niklas, Richter, S. Helene, Urbanik, Sarah, Kunert, Joachim, Waider, Jonas, Lesch, Klaus-Peter, Kaiser, Sylvia, Sachser, Norbert

“…The neurotransmitter serotonin plays a key role in the control of aggressive behaviour. While so far most studies have investigated variation in serotonin…”
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Heterogenising study samples across testing time improves reproducibility of behavioural data by Bodden, Carina, von Kortzfleisch, Vanessa Tabea, Karwinkel, Fabian, Kaiser, Sylvia, Sachser, Norbert, Richter, S. Helene

“…The ongoing debate on the reproducibility crisis in the life sciences highlights the need for a rethinking of current methodologies. Since the trend towards…”
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Reproducibility and replicability of rodent phenotyping in preclinical studies by Kafkafi, Neri, Agassi, Joseph, Chesler, Elissa J., Crabbe, John C., Crusio, Wim E., Eilam, David, Gerlai, Robert, Golani, Ilan, Gomez-Marin, Alex, Heller, Ruth, Iraqi, Fuad, Jaljuli, Iman, Karp, Natasha A., Morgan, Hugh, Nicholson, George, Pfaff, Donald W., Richter, S. Helene, Stark, Philip B., Stiedl, Oliver, Stodden, Victoria, Tarantino, Lisa M., Tucci, Valter, Valdar, William, Williams, Robert W., Würbel, Hanno, Benjamini, Yoav

“…•Many published scientific discoveries fail to replicate.•The field of mouse behavioral phenotyping was one of the first to raise this concern.•Replicability…”
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Do multiple experimenters improve the reproducibility of animal studies? by von Kortzfleisch, Vanessa Tabea, Ambrée, Oliver, Karp, Natasha A, Meyer, Neele, Novak, Janja, Palme, Rupert, Rosso, Marianna, Touma, Chadi, Würbel, Hanno, Kaiser, Sylvia, Sachser, Norbert, Richter, S Helene

“…The credibility of scientific research has been seriously questioned by the widely claimed "reproducibility crisis". In light of this crisis, there is a…”
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Systematic variation improves reproducibility of animal experiments by Würbel, Hanno, Richter, S Helene, Garner, Joseph P, Auer, Corinna, Kunert, Joachim

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Automated Home-Cage Testing as a Tool to Improve Reproducibility of Behavioral Research? by Richter, Sophie Helene

“…Against this background, the present opinion paper aims at (1) briefly discussing the role of the experimenter in animal studies, (2) investigating the…”
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Behavioral lateralization of mice varying in serotonin transporter genotype by Stieger, Binia, Wesseler, Yvonne, Kaiser, Sylvia, Sachser, Norbert, Richter, S Helene

“…In humans, non-right-handedness is associated with a higher incidence of psychiatric disorders. Since serotonin seems to be involved in both, the development…”
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Correction: Do multiple experimenters improve the reproducibility of animal studies? by von Kortzfleisch, Vanessa Tabea, Ambrée, Oliver, Karp, Natasha A, Meyer, Neele, Novak, Janja, Palme, Rupert, Rosso, Marianna, Touma, Chadi, Würbel, Hanno, Kaiser, Sylvia, Sachser, Norbert, Richter, S Helene

“…[This corrects the article DOI: 10.1371/journal.pbio.3001564.]…”
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The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level by Jaric, Ivana, Voelkl, Bernhard, Clerc, Melanie, Schmid, Marc W, Novak, Janja, Rosso, Marianna, Rufener, Reto, von Kortzfleisch, Vanessa Tabea, Richter, S. Helene, Buettner, Manuela, Bleich, André, Amrein, Irmgard, Wolfer, David P, Touma, Chadi, Sunagawa, Shinichi, Würbel, Hanno

“…The phenotype of an organism results from its genotype and the influence of the environment throughout development. Even when using animals of the same…”
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A Time to Wean? Impact of Weaning Age on Anxiety-Like Behaviour and Stability of Behavioural Traits in Full Adulthood by Richter, S Helene, Kästner, Niklas, Loddenkemper, Dirk-Heinz, Kaiser, Sylvia, Sachser, Norbert

“…In mammals, weaning constitutes an important phase in the progression to adulthood. It comprises the termination of suckling and is characterized by several…”
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The power of a touch: Regular touchscreen training but not its termination affects hormones and behavior in mice by Quante, Sophia Marie, Siewert, Viktoria, Palme, Rupert, Kaiser, Sylvia, Sachser, Norbert, Richter, S Helene

“…Touchscreen-based procedures are increasingly used in experimental animal research. They not only represent a promising approach for translational research,…”
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Repeatability of endocrine traits and dominance rank in female guinea pigs by Rystrom, Taylor L, Prawitt, Romy C, Richter, S Helene, Sachser, Norbert, Kaiser, Sylvia

“…Glucocorticoids (e.g. cortisol) are associated with variation in social behavior, and previous studies have linked baseline as well as challenge-induced…”
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Differential Effects of Serotonin Transporter Genotype on Anxiety-Like Behavior and Cognitive Judgment Bias in Mice by Krakenberg, Viktoria, von Kortzfleisch, Vanessa Tabea, Kaiser, Sylvia, Sachser, Norbert, Richter, S Helene

“…In humans, the short allele of a common polymorphism in the serotonin transporter (5-HTT) gene is associated with a higher risk to develop depression and…”
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Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study by Richter, S Helene, Garner, Joseph P, Zipser, Benjamin, Lewejohann, Lars, Sachser, Norbert, Touma, Chadi, Schindler, Britta, Chourbaji, Sabine, Brandwein, Christiane, Gass, Peter, van Stipdonk, Niek, van der Harst, Johanneke, Spruijt, Berry, Võikar, Vootele, Wolfer, David P, Würbel, Hanno

“…In animal experiments, animals, husbandry and test procedures are traditionally standardized to maximize test sensitivity and minimize animal use, assuming…”
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Structural enrichment for laboratory mice: exploring the effects of novelty and complexity by Bohn, Lena, Bierbaum, Louisa, Kästner, Niklas, von Kortzfleisch, Vanessa Tabea, Kaiser, Sylvia, Sachser, Norbert, Richter, S. Helene

“…Providing structural enrichment is a widespread refinement method for laboratory rodents and other animals in captivity. So far, animal welfare research has…”
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