Search Results - "Richter, Guenther Hs"

Distinct transcriptional signature and immunoprofile of CIC-DUX4 fusion-positive round cell tumors compared to EWSR1-rearranged ewing sarcomas: Further evidence toward distinct pathologic entities by Specht, Katja, Sung, Yun-Shao, Zhang, Lei, Richter, Günther H. S., Fletcher, Christopher D., Antonescu, Cristina R.

“…Round cell sarcomas harboring CIC‐DUX4 fusions have recently been described as highly aggressive soft tissue tumors of children and young adults. Due to…”
Get full text

Abstract A48: YB-1-based oncolytic virotherapy in combination with CDK4/6-inhibitors against Ewing sarcoma by Schober, Sebastian J., Thiel, Uwe, Thiede, Melanie, Ehrenfeld, Maximilian, Nawroth, Roman, Richter, Guenther HS, Burdach, Stefan E.G., Holm, Per Sonne

“…Oncolytic virotherapy is associated with immunogenic cell death and antitumor inflammatory immune responses. Thereby, a local as well as systemic…”
Get full text

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma by Agelopoulos, Konstantin, Richter, Günther H S, Schmidt, Eva, Dirksen, Uta, von Heyking, Kristina, Moser, Benjamin, Klein, Hans-Ulrich, Kontny, Udo, Dugas, Martin, Poos, Kathrin, Korsching, Eberhard, Buch, Thorsten, Weckesser, Matthias, Schulze, Isabell, Besoke, Regina, Witten, Anika, Stoll, Monika, Köhler, Gabriele, Hartmann, Wolfgang, Wardelmann, Eva, Rossig, Claudia, Baumhoer, Daniel, Jürgens, Heribert, Burdach, Stefan, Berdel, Wolfgang E, Müller-Tidow, Carsten

“…A low mutation rate seems to be a general feature of pediatric cancers, in particular in oncofusion gene-driven tumors. Genetically, Ewing sarcoma is defined…”
Get full text

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation by Richter, Günther H.S, Plehm, Stephanie, Fasan, Annette, Rössler, Sabine, Unland, Rebekka, Bennani-Baiti, Idriss M, Hotfilder, Marc, Löwel, Diana, von Luettichau, Irene, Mossbrugger, Ilona, Quintanilla-Martinez, Leticia, Kovar, Heinrich, Staege, Martin S, Müller-Tidow, Carsten, Burdach, Stefan

“…Ewing tumors (ET) are highly malignant, localized in bone or soft tissue, and are molecularly defined by ews/ets translocations. DNA microarray analysis…”
Get full text

Abstract A51: The HoxD locus: Its contribution to osteogenic phenotype and malignancy of Ewing sarcoma by Richter, Guenther HS, Heyking, Kristina von, Roth, Laura, Ertl, Miriam, Burdach, Stefan

“…Ewing sarcoma (ES), an osteogenic malignancy that mainly affects children and young adults, is characterized by early metastasis to lung and bone. Microarray…”
Get full text

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma by von Heyking, Kristina, Roth, Laura, Ertl, Miriam, Schmidt, Oxana, Calzada-Wack, Julia, Neff, Frauke, Lawlor, Elizabeth R, Burdach, Stefan, Richter, Guenther Hs

“…Microarray analysis revealed genes of the posterior HOXD locus normally involved in bone formation to be over-expressed in primary Ewing sarcoma (ES). The…”
Get full text

Epigenetic repression of the dopamine receptor D4 in pediatric tumors of the central nervous system by Unland, Rebekka, Kerl, Kornelius, Schlosser, Sabrina, Farwick, Nicole, Plagemann, Tanja, Lechtape, Birigit, Clifford, Steven C., Kreth, Jonas H., Gerss, Joachim, Mühlisch, Jörg, Richter, Günther H. S., Hasselblatt, Martin, Frühwald, Michael C.

“…Epigenetic alterations are common events in cancer. Using a genome wide methylation screen (Restriction Landmark Genomic Scanning—RLGS) we identified the gene…”
Get full text