Search Results - "Richman, D P"

An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis by SANDERS, D. B, HART, I. K, MANTEGAZZA, R, SHUKLA, S. S, SIDDIQI, Z. A, DE BAETS, M. H. V, MELMS, A, NICOLLE, M. W, SOLOMONS, N, RICHMAN, D. P

“…This prospective, randomized, double-blind, placebo-controlled, phase III trial assessed the efficacy, safety, and tolerability of mycophenolate mofetil (MMF)…”
Get full text

Lipoprotein-like receptor 4 antibodies in myasthenia gravis: pathogenic or protective by Richman, D. P.

“…Click here to view the accompanying paper in this issue…”
Get full text

Presynaptic congenital myasthenic syndrome due to quantal release deficiency by MASELLI, R. A, KONG, D. Z, BOWE, C. M, MCDONALD, C. M, ELLIS, W. G, AGIUS, M. A, GOMEZ, C. M, RICHMAN, D. P, WOLLMANN, R. L

“…To provide clinical, electrophysiologic, and ultrastructural findings in three patients with a presynaptic congenital myasthenic syndrome (CMS). Familial…”
Get full text

Transcervical thymectomy for myasthenia gravis by DeFilippi, Vincent J., Richman, David P., Ferguson, Mark K.

“…The use of transcervical thymectomy in the treatment of myasthenia gravis remains controversial. We retrospectively reviewed our experience with this procedure…”
Get full text

Neuromuscular transmission in amyotrophic lateral sclerosis by Maselli, R A, Wollman, R L, Leung, C, Distad, B, Palombi, S, Richman, D P, Salazar-Grueso, E F, Roos, R P

“…The functional and structural characteristics of the neuromuscular junction were studied in anconeus muscle biopsies of 10 patients with amyotrophic lateral…”
Get more information

Cluster of wound botulism in California: Clinical, electrophysiologic, and pathologic study by Maselli, Ricardo A., Ellis, William, Mandler, Raul N., Sheikh, Firdos, Venton, Grace, Knox, Stephen, Salari-Namin, Hamid, Agius, Mark, Wollmann, Robert L., Richman, David P.

“…Over a period of 15 months we have seen 6 patients with long‐standing history of subcutaneous heroin injections who experienced acute blurred vision,…”
Get full text

Inflammation at the neuromuscular junction in myasthenia gravis by MASELLI, R. A, RICHMAN, D. P, WOLLMANN, R. L

“…To better define the pathogenic mechanisms in the antibody-mediated autoimmune disease myasthenia gravis (MG), we analyzed the morphology and electrophysiology…”
Get full text

Monoclonal antibodies as probes of the alpha-bungarotoxin and cholinergic binding regions of the acetylcholine receptor by Mihovilovic, M., Richman, D.P.

“…We have probed the acetylcholine receptor (AcChR) molecule with six anti-AcChR monoclonal antibodies (mAbs) whose binding to the AcChR is inhibited or blocked…”
Get full text

Anti-Acetylcholine Receptor Antibodies Directed against the α -bungarotoxin Binding Site Induce a Unique Form of Experimental Myasthenia by Gomez, Christopher M., Richman, David P.

“…Of seven rat monoclonal antibodies directed against nicotinic acetylcholine receptor, the three whose binding was blocked by α -bungarotoxin produced acute…”
Get full text

Myasthenia gravis: pathogenesis and treatment by Richman, D P, Agius, M A

“…Much is known about the pathogenesis of MG. This information has provided a rational basis for treatment of the disease, which is very effective. On the other…”
Get more information

Monoclonal anti-acetylcholine receptor antibodies with differing capacities to induce experimental autoimmune myasthenia gravis by Gomez, CM, Richman, DP

“…To study the characteristics of the individual autoantibodies that are important in the development of an autoimmune disease, we produced 26 anti-acetylcholine…”
Get full text

Effects of a monoclonal anti-acetylcholine receptor antibody on the avian end-plate by Maselli, R A, Nelson, D J, Richman, D P

“…1. The effects of anti-acetylcholine receptor (AChR) monoclonal antibodies (mAbs) 370 and 132A on miniature end-plate potentials (MEPPs) and end-plate currents…”
Get full text

Nicotinic Acetylcholine Receptor: Evidence for a Functionally Distinct Receptor on Human Lymphocytes by Richman, David P., Barry G. W. Arnason

“…The presence of three distinct cholinergic receptors on human lymphocytes was suggested by the effects of carbamoylcholine on lymphocyte proliferation in…”
Get full text

Modification of alpha-bungarotoxin and cholinergic ligand-binding properties of Torpedo acetylcholine receptor by a monoclonal anti-acetylcholine receptor antibody by Mihovilovic, M, Richman, D P

“…The interaction between acetylcholine receptor (AcChR) and monoclonal antibody (mab) 247G–whose binding is blocked by the presence of alpha-bungarotoxin (alpha…”
Get full text

Thymectomy in the treatment of ocular myasthenia gravis by Roberts, Peter F., Venuta, Federico, Rendina, Erino, De Giacomo, Tiziana, Coloni, Giorgio F., Follette, David M., Richman, David P., Benfield, John R.

“…Background: Thymectomy is an effective and accepted treatment for myasthenia gravis, but thymectomy for ocular myasthenia gravis (Osserman stage I) is…”
Get full text

Acquired myasthenia gravis. Immunopathology by Richman, D P, Agius, M A

“…Much of the remarkable advance in our understanding of the immunopathology of MG relates to the availability of two gifts of nature that permit the ready…”
Get more information

Suppression of development of experimental autoimmune myasthenia gravis with isogeneic monoclonal antiidiotopic antibody by AGIUS, M. A, RICHMAN, D. P

Get full text

Refractoriness to a second episode of experimental myasthenia gravis. Correlation with AChR concentration and morphologic appearance of the postsynaptic membrane by Corey, AL, Richman, DP, Agius, MA, Wollmann, RL

“…Rats injected with anti-acetylcholine receptor (anti-AChR)2 monoclonal antibodies (mAb) develop the acute phase of experimental autoimmune myasthenia gravis…”
Get full text

Chronic experimental autoimmune myastenia gravis induced by monoclonal antibody to acetylcholine receptor: biochemical and electrophysiologic criteria by GOMEZ, C. M, RICHMAN, D. P

Get full text

Induction of the morphologic changes of both acute and chronic experimental myasthenia by monoclonal antibody directed against acetylcholine receptor by GOMEZ, C. M, WOLLMANN, R. L, RICHMAN, D. P

“…To investigate pathogenic mechanisms in experimental autoimmune myasthenia gravis (EAMG) and myasthenia gravis (MG), we studied the acute and chronic effects…”
Get full text