Search Results - "Richie, E"

Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacers by Kohman, Richie E, Han, Xue

“…Using light irradiation as a trigger, large-scale structural reconfiguration of DNA nanostructures is demonstrated. We incorporated photo-cleavable spacers at…”
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Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage by Lee, Howon, Wiegand, Daniel J., Griswold, Kettner, Punthambaker, Sukanya, Chun, Honggu, Kohman, Richie E., Church, George M.

“…New storage technologies are needed to keep up with the global demands of data generation. DNA is an ideal storage medium due to its stability, information…”
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Light-Triggered Release of Bioactive Molecules from DNA Nanostructures by Kohman, Richie E, Cha, Susie S, Man, Heng-Ye, Han, Xue

“…Recent innovations in DNA nanofabrication allow the creation of intricately shaped nanostructures ideally suited for many biological applications. To advance…”
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Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions by Wang, Yu, Liu, Xiaoyu, Zeng, Yitian, Saka, Sinem K, Xie, Wenxin, Goldaracena, Isabel, Kohman, Richie E, Yin, Peng, Church, George M

“…Abstract Antibodies have long served as vital tools in biological and clinical laboratories for the specific detection of proteins. Conventional methods employ…”
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Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression by Pierson Smela, Merrick D, Kramme, Christian C, Fortuna, Patrick R J, Adams, Jessica L, Su, Rui, Dong, Edward, Kobayashi, Mutsumi, Brixi, Garyk, Kavirayuni, Venkata Srikar, Tysinger, Emma, Kohman, Richie E, Shioda, Toshi, Chatterjee, Pranam, Church, George M

“…An in vitro model of human ovarian follicles would greatly benefit the study of female reproduction. Ovarian development requires the combination of germ cells…”
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A comprehensive library of human transcription factors for cell fate engineering by Ng, Alex H. M., Khoshakhlagh, Parastoo, Rojo Arias, Jesus Eduardo, Pasquini, Giovanni, Wang, Kai, Swiersy, Anka, Shipman, Seth L., Appleton, Evan, Kiaee, Kiavash, Kohman, Richie E., Vernet, Andyna, Dysart, Matthew, Leeper, Kathleen, Saylor, Wren, Huang, Jeremy Y., Graveline, Amanda, Taipale, Jussi, Hill, David E., Vidal, Marc, Melero-Martin, Juan M., Busskamp, Volker, Church, George M.

“…Human pluripotent stem cells (hPSCs) offer an unprecedented opportunity to model diverse cell types and tissues. To enable systematic exploration of the…”
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Recovery of walking after paralysis by regenerating characterized neurons to their natural target region by Squair, Jordan W., Milano, Marco, de Coucy, Alexandra, Gautier, Matthieu, Skinnider, Michael A., James, Nicholas D., Cho, Newton, Lasne, Anna, Kathe, Claudia, Hutson, Thomas H., Ceto, Steven, Baud, Laetitia, Galan, Katia, Aureli, Viviana, Laskaratos, Achilleas, Barraud, Quentin, Deming, Timothy J., Kohman, Richie E., Schneider, Bernard L., He, Zhigang, Bloch, Jocelyne, Sofroniew, Michael V., Courtine, Gregoire, Anderson, Mark A.

“…Axon regeneration can be induced across anatomically complete spinal cord injury (SCI), but robust functional restoration has been elusive. Whether restoring…”
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From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies by Kohman, Richie E., Kunjapur, Aditya M., Hysolli, Eriona, Wang, Yu, Church, George M.

“…Since the elucidation of its structure, DNA has been at the forefront of biological research. In the past half century, an explosion of DNA‐based technology…”
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A SARS‐CoV‐2 Neutralization Assay Using Single Molecule Arrays by Gilboa, Tal, Cohen, Limor, Cheng, Chi‐An, Lazarovits, Roey, Uwamanzu‐Nna, Augusta, Han, Isaac, Griswold, Kettner, Barry, Nick, Thompson, David B., Kohman, Richie E., Woolley, Ann E., Karlson, Elizabeth W., Walt, David R.

“…Coronavirus disease 2019 (COVID‐19) manifests with high clinical variability and warrants sensitive and specific assays to analyze immune responses in infected…”
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Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses by Liu, Songlei, Punthambaker, Sukanya, Iyer, Eswar P R, Ferrante, Thomas, Goodwin, Daniel, Fürth, Daniel, Pawlowski, Andrew C, Jindal, Kunal, Tam, Jenny M, Mifflin, Lauren, Alon, Shahar, Sinha, Anubhav, Wassie, Asmamaw T, Chen, Fei, Cheng, Anne, Willocq, Valerie, Meyer, Katharina, Ling, King-Hwa, Camplisson, Conor K, Kohman, Richie E, Aach, John, Lee, Je Hyuk, Yankner, Bruce A, Boyden, Edward S, Church, George M

“…Abstract We present barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel insitu analyses (BOLORAMIS), a reverse transcription-free…”
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Microscale direct measurement of localized photothermal heating in tissue-mimetic hydrogels by Davaji, Benyamin, Richie, James E., Lee, Chung Hoon

“…Photothermal hyperthermia is proven to be an effective diagnostic tool for cancer therapy. The efficacy of this method directly relies on understanding the…”
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Biodegradable Polymer Crosslinker: Independent Control of Stiffness, Toughness, and Hydrogel Degradation Rate by Cha, Chaenyung, Kohman, Richie H., Kong, Hyunjoon

“…Hydrogels are being increasingly studied for use in various biomedical applications including drug delivery and tissue engineering. The successful use of a…”
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How collaboration between bioethicists and neuroscientists can advance research by Hyun, Insoo, Scharf-Deering, J. C., Sullivan, Sarah, Aach, John Dennis, Arlotta, Paola, Baum, Matthew L., Church, George M., Goldenberg, Aaron, Greely, Henry T., Khoshakhlagh, Parastoo, Kohman, Richie E., Lopes, Melissa, Lowenthal, Caroline, Lu, Aric, Ng, Alex H. M., Pasca, Sergiu P., Paulsen, Bruna, Pigoni, Martina, Scott, Christopher T., Silbersweig, David A., Skylar-Scott, Mark A., Truog, Robert D., Lunshof, Jeantine E.

“…By integrating ongoing bioethical collaboration, neuroscientists can create a positive effect on their research and the knowledge it produces. To this end, we…”
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Permeabilization of the blood-brain barrier via mucosal engrafting: implications for drug delivery to the brain by Bleier, Benjamin S, Kohman, Richie E, Feldman, Rachel E, Ramanlal, Shreshtha, Han, Xue

“…Utilization of neuropharmaceuticals for central nervous system(CNS) disease is highly limited due to the blood-brain barrier(BBB) which restricts molecules…”
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Leukocyte-Mimicking Stem Cell Delivery via in Situ Coating of Cells with a Bioactive Hyperbranched Polyglycerol by Jeong, Jae Hyun, Schmidt, John J, Kohman, Richie E, Zill, Andrew T, DeVolder, Ross J, Smith, Cartney E, Lai, Mei-Hsiu, Shkumatov, Artem, Jensen, Tor W, Schook, Lawrence G, Zimmerman, Steven C, Kong, Hyunjoon

“…Since stem cells emerged as a new generation of medicine, there are increasing efforts to deliver stem cells to a target tissue via intravascular injection…”
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Challenges Incarcerated Women Face as They Return to Their Communities: Findings from Life History Interviews by Richie, Beth E.

“…This article uses results of a qualitative research project to describe the challenges that incarcerated women face as they return to their communities from…”
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On-chip detection of gel transition temperature using a novel micro-thermomechanical method by Byambadorj, Tsenguun, Dashtimoghadam, Erfan, Malakoutian, Mohamadali, Davaji, Benyamin, Tayebi, Lobat, Richie, James E, Lee, Chung Hoon

“…We present a new thermomechanical method and a platform to measure the phase transition temperature at microscale. A thin film metal sensor on a membrane…”
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Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers by Kobayashi, Mutsumi, Kobayashi, Misato, Odajima, Junko, Shioda, Keiko, Hwang, Young Sun, Sasaki, Kotaro, Chatterjee, Pranam, Kramme, Christian, Kohman, Richie E., Church, George M., Loehr, Amanda R., Weiss, Robert S., Jüppner, Harald, Gell, Joanna J., Lau, Ching C., Shioda, Toshi

“…In vitro expansion of human primordial germ cell-like cells (hPGCLCs), a pluripotent stem cell-derived PGC model, has proved challenging due to rapid loss of…”
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Minibrains: What's in a Name? by Lopes, Melissa, Kohman, Richie, Lunshof, Jeantine, Paulsen, Bruna, Pigoni, Martina, White, Alexandra, Aach, John, Hyun, Insoo

“…The human brain is incredibly complex and relies on inputs and other senses as well as outgoing connections to human tissues. One needs only to look at a baby…”
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Coming Home From Jail: The Social and Health Consequences of Community Reentry for Women, Male Adolescents, and Their Families and Communities by Freudenberg, Nicholas, Daniels, Jessie, Crum, Martha, Perkins, Tiffany, Richie, Beth E

“…Each year, more than 10 million people enter US jails, most returning home within a few weeks. Because jails concentrate people with infectious and chronic…”
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