Search Results - "Richetta, Clémence"
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1
Sustained autophagy contributes to measles virus infectivity
Published in PLoS pathogens (01-09-2013)“…The interplay between autophagy and intracellular pathogens is intricate as autophagy is an essential cellular response to fight against infections, whereas…”
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2
Autophagy induction by the pathogen receptor CD46
Published in Cell host & microbe (22-10-2009)“…Autophagy is a highly regulated self-degradative mechanism required at a basal level for intracellular clearance and recycling of cytoplasmic contents. Upon…”
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3
Differential activation of human neutrophils by SARS-CoV-2 variants of concern
Published in Frontiers in immunology (27-10-2022)“…The emerging SARS-CoV-2 virus has affected the entire world with over 600 million confirmed cases and 6.5 million deaths as of September 2022. Since the…”
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4
Reply to Das and Berkhout, "How Polypurine Tract Changes in the HIV-1 RNA Genome Can Cause Resistance against the Integrase Inhibitor Dolutegravir"
Published in mBio (29-05-2018)Get full text
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5
Autophagy in antiviral innate immunity
Published in Cellular microbiology (01-03-2013)“…Summary Several autonomous arms of innate immunity help cells to combat viral infections. One of these is autophagy, a central cytosolic lysosomal‐dependent…”
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Different Pathways Conferring Integrase Strand-Transfer Inhibitors Resistance
Published in Viruses (22-11-2022)“…Integrase Strand Transfer Inhibitors (INSTIs) are currently used as the most effective therapy in the treatment of human immunodeficiency virus (HIV)…”
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7
Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration
Published in Journal of virology (27-07-2022)“…Integration of the reverse-transcribed genome is a critical step of the retroviral life cycle. Strand-transfer inhibitors (INSTIs) used for antiretroviral…”
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8
IRGM is a common target of RNA viruses that subvert the autophagy network
Published in PLoS pathogens (01-12-2011)“…Autophagy is a conserved degradative pathway used as a host defense mechanism against intracellular pathogens. However, several viruses can evade or subvert…”
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9
Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase
Published in The Journal of biological chemistry (17-05-2019)“…Integration of the HIV-1 DNA into the host genome is essential for viral replication and is catalyzed by the retroviral integrase. To date, the only substrate…”
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10
Interplay between Intrinsic and Innate Immunity during HIV Infection
Published in Cells (Basel, Switzerland) (17-08-2019)“…Restriction factors are antiviral components of intrinsic immunity which constitute a first line of defense by blocking different steps of the human…”
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The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC‐II molecules
Published in EMBO reports (06-12-2022)“…CD4 + T lymphocytes play a major role in the establishment and maintenance of immunity. They are activated by antigenic peptides derived from extracellular or…”
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12
HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells
Published in The Journal of immunology (1950) (15-07-2016)“…It is widely assumed that CD4(+) T cells recognize antigenic peptides (epitopes) derived solely from incoming, exogenous, viral particles or proteins. However,…”
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13
Triggering of TLR‐3, ‐4, NOD2, and DC‐SIGN reduces viral replication and increases T‐cell activation capacity of HIV‐infected human dendritic cells
Published in European journal of immunology (01-05-2017)“…A variety of signals influence the capacity of dendritic cells (DCs) to mount potent antiviral cytotoxic T‐cell (CTL) responses. In particular, innate immune…”
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14
The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection
Published in Frontiers in immunology (18-10-2023)“…Purinergic receptors and NOD-like receptor protein 3 (NLRP3) inflammasome regulate inflammation and viral infection, but their effects on severe acute…”
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15
HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
Published in EBioMedicine (01-07-2017)“…HIV-specific broadly neutralizing antibodies (bnAbs) have been isolated from patients with high viremia but also from HIV controllers that repress HIV-1…”
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16
Autophagy Receptors in the presentation of Viral antigens by MHC-II molecules
Published in Molecular immunology (01-10-2022)“…CD4+ T lymphocytes play a major role in the establishment and maintenance of antiviral immunity. CD4+ T cells are activated by antigenic peptides, derived from…”
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17
Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces
Published in Antimicrobial agents and chemotherapy (16-08-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the infectious agent that has caused the current coronavirus disease (COVID) pandemic. Viral…”
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18
Sustained Autophagy Contributes to Measles Virus Infectivity: e1003599
Published in PLoS pathogens (01-09-2013)“…The interplay between autophagy and intracellular pathogens is intricate as autophagy is an essential cellular response to fight against infections, whereas…”
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19
The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection
Published in Frontiers in immunology (18-10-2023)“…Abstract Purinergic receptors and NOD-like receptor protein 3 (NLRP3) inflammasome regulate inflammation and viral infection, but their effects on severe acute…”
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