Search Results - "Riches, Christine"

1311-P: Glucokinase in AGRP Neurons Is Required for Normal Insulin Secretion and Action in Female Mice by JOSIPOVIC, MASA, STARICOFF, EMILY O., RICHES, CHRISTINE H., SHEPPARD, LAURA, EVANS, MARK

“…Discrete brain areas, including hypothalamic nuclei, have been implicated in glucose homeostasis. Some contain molecular machinery capable of detecting changes…”
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Molecular reductions in glucokinase activity increase counter-regulatory responses to hypoglycemia in mice and humans with diabetes by Chakera, Ali J., Hurst, Paul S., Spyer, Gill, Ogunnowo-Bada, Emmanuel O., Marsh, William J., Riches, Christine H., Yueh, Chen-Yu, Markkula, S. Pauliina, Dalley, Jeffrey W., Cox, Roger D., Macdonald, Ian A., Amiel, Stephanie A., MacLeod, Kenneth M., Heisler, Lora K., Hattersley, Andrew T., Evans, Mark L.

“…Appropriate glucose levels are essential for survival; thus, the detection and correction of low blood glucose is of paramount importance. Hypoglycemia prompts…”
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Lorcaserin improves glycemic control via a melanocortin neurocircuit by Burke, Luke K., Ogunnowo-Bada, Emmanuel, Georgescu, Teodora, Cristiano, Claudia, de Morentin, Pablo B. Martinez, Valencia Torres, Lourdes, D'Agostino, Giuseppe, Riches, Christine, Heeley, Nicholas, Ruan, Yue, Rubinstein, Marcelo, Low, Malcolm J., Myers, Martin G., Rochford, Justin J., Evans, Mark L., Heisler, Lora K.

“…The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the…”
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Recurrent hypoglycemia increases hypothalamic glucose phosphorylation activity in rats by Osundiji, Mayowa A, Hurst, Paul, Moore, Stephen P, Markkula, S. Pauliina, Yueh, Chen Y, Swamy, Ashwini, Hoashi, Shu, Shaw, Jill S, Riches, Christine H, Heisler, Lora K, Evans, Mark L

“…Abstract The mechanisms underpinning impaired defensive counterregulatory responses to hypoglycemia that develop in some people with diabetes who suffer…”
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Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats by Pauliina Markkula, S, Lyons, David, Yueh, Chen-Yu, Riches, Christine, Hurst, Paul, Fielding, Barbara, Heisler, Lora K, Evans, Mark L

“…Specialized metabolic sensors in the hypothalamus regulate blood glucose levels by influencing hepatic glucose output and hypoglycemic counterregulatory…”
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