Search Results - "Richert, John R"
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Neuropsychological effects of interferon β-1a in relapsing multiple sclerosis
Published in Annals of neurology (01-12-2000)“…Cognitive dysfunction is common in multiple sclerosis (MS), yet few studies have examined effects of treatment on neuropsychological (NP) performance. To…”
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Eight-year immunogenicity and safety of interferon beta-1a-Avonex®treatment in patients with multiple sclerosis
Published in Multiple sclerosis (01-08-2005)“…An open-label extension study of the phase III trial of intramuscular interferon beta-1a (IFNβ-1a-Avonex) was conducted to evaluate the immunogenicity and…”
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A phase I study of the safety of honeybee venom extract as a possible treatment for patients with progressive forms of multiple sclerosis
Published in Allergy and asthma proceedings (01-11-2005)“…Although several reports suggest that bee venom may be an effective treatment for patients with multiple sclerosis (MS), patients may be subjected to real…”
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Selecting a disease-modifying agent as platform therapy in the long-term management of multiple sclerosis
Published in Neurology (14-12-2004)“…Multiple sclerosis (MS) is a complex, incurable disease. Treatment consists of lifelong disease and symptom management. FDA-approved therapies for relapsing MS…”
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Structure-Based Discovery of Nonpeptidic Small Organic Compounds To Block the T Cell Response to Myelin Basic Protein
Published in Journal of medicinal chemistry (07-10-2004)“…We have utilized a computational structure-based approach to identify nonpeptidic small organic compounds that bind to a human leukocyte antigen (HLA) DR1301…”
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Sp3 Expression in Immune Cells: A Quantitative Study
Published in Laboratory investigation (01-09-2002)“…We previously reported the lack of expression of the bifunctional transcription factor Sp3 in peripheral blood mononuclear cells from most patients with…”
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Human transcription factor Sp3: genomic structure, identification of a processed pseudogene, and transcript analysis
Published in Gene (27-10-2004)“…The human transcription factor Sp3 has been widely studied at the translational level and has been described as a regulatory factor for a number of genes. Sp3…”
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Role of an internal ribosome entry site in the translational control of the human transcription factor Sp3
Published in International journal of oncology (01-03-2004)“…Sp1 and Sp3 are transcription factors involved in the regulation of numerous genes involved in oncogenesis. Sp3 is a bi-functional transcription factor with…”
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AUA as a translation initiation site in vitro for the human transcription factor Sp3
Published in Journal of biochemistry and molecular biology (31-05-2002)“…Sp3 is a bifunctional transcription factor that has been reported to stimulate or repress the transcription of numerous genes. Although the size of Sp3 mRNA is…”
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Localization of the human SP3 gene to chromosome 7p14–p15.2. The lack of expression in multiple sclerosis does not reflect abnormal gene organization
Published in Journal of neuroimmunology (01-07-2000)“…Sp3 belongs to a large family of transcription factors that bind GC/T box elements. We have previously demonstrated the deficient expression of Sp3 in…”
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Demyelination occurring during anti-tumor necrosis factor a therapy for inflammatory arthritides
Published in Arthritis and rheumatism (01-12-2001)Get full text
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Measles vaccine failures: lack of sustained measles-specific immunoglobulin G responses in revaccinated adolescents and young adults
Published in The Pediatric infectious disease journal (01-01-1994)“…The measles-specific antibody responses of seronegative adolescents and young adults were evaluated after revaccination. Of 1650 previously vaccinated healthy…”
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CSF antibodies for dynorphin bind synthetic Staphylococcus aureus replication protein B 275-290
Published in Biological psychiatry (1969) (01-10-1994)Get more information
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Adoptive Transfer of Experimental Allergic Encephalomyelitis: Incubation of Rat Spleen Cells with Specific Antigen
Published in The Journal of immunology (1950) (01-02-1979)“…Spleen cells from myelin basic protein (BP)-sensitized donor rats appear to be incapable of adoptively transferring experimental allergic encephalomyelitis…”
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Open label gabapentin treatment for pain in multiple sclerosis
Published in Multiple sclerosis (01-08-1997)“…Pain is a frequent and distressing complaint in patients with multiple sclerosis (MS) and may present a difficult therapeutic problem. Conventional therapy is…”
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Multiple Sclerosis: Current Status of Research and Treatment
Published in Neurology (01-06-1995)Get full text
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Cerebrospinal fluid abnormalities in a phase III trial of Avonex® (IFNβ-1a) for relapsing multiple sclerosis
Published in Journal of neuroimmunology (1999)“…Background and objective: This report provides results of CSF analyses done in a subset of relapsing remitting MS patients participating in a…”
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Eight-year immunogenicity and safety of interferon beta-la-avonex® treatment in patients with multiple sclerosis
Published in Multiple sclerosis (2005)Get full text
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Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106
Published in The Journal of immunology (1950) (01-03-1992)“…Multiple sclerosis (MS), a human demyelinating disease, is thought to be caused by an autoimmunologic process, and myelin basic protein (MBP) is considered a…”
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