Search Results - "Richert, J. R."

Differential diagnosis of suspected multiple sclerosis: a consensus approach by Miller, DH, Weinshenker, BG, Filippi, M, Banwell, BL, Cohen, JA, Freedman, MS, Galetta, SL, Hutchinson, M, Johnson, RT, Kappos, L, Kira, J, Lublin, FD, McFarland, HF, Montalban, X, Panitch, H, Richert, JR, Reingold, SC, Polman, CH

“…Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases that could better explain the clinical and paraclinical findings…”
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Serum IL-17F does not predict poor response to IM IFNβ-1a in relapsing-remitting MS by BUSHNELL, S. E, ZHAO, Z, STEINMAN, L, MEDORI, R, STEBBINS, C. C, CADAVID, D, BUKO, A. M, WHALLEY, E. T, DAVIS, J. A, VERSAGE, E. M, RICHERT, J. R, AXTELL, R. C

“…There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response to…”
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Incidence and significance of neutralizing antibodies to interferon beta-1a in multiple sclerosis by RUDICK, R. A, SIMONIAN, N. A, MASS, M. K, RICHERT, J. R, SALAZAR, A. M, MUNSCHBAUER, F. E, COOKFAIR, D. L, SIMON, J. H, JACOBS, L. D, ALAM, J. A, CAMPION, M, SCARAMUCCI, J. O, JONES, W, COATS, M. E, GOODKIN, D. E, WEINSTOCK-GUTTMAN, B, HERNDON, R. M

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Proof of concept studies for tissue-protective agents in multiple sclerosis by Mehta, LR, Schwid, SR, Arnold, DL, Cutter, GR, Aradhye, S, Balcer, LJ, Calabresi, PA, Cohen, JA, Cole, PE, Glanzman, R, Goelz, S, Inglese, M, Kapoor, R, Kappos, L, Kreitman, R, Lublin, FD, Mann, A, Marrie, RA, O'Looney, P, Polman, CH, Ravina, BM, Reingold, SC, Richert, JR, Sandrock, AW, Waubant, E

“…Background There is considerable interest in tissue-protective treatments for multiple sclerosis (MS). Methods and Objectives We convened a group of MS…”
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Short-Term Relapse Quantitation as a Fully Surrogate Endpoint for Long-Term Sustained Progression of Disability in RRMS Patients Treated with Natalizumab by Meyerson, L., Sandrock, A., Richert, J. R., Miao, X., Wang, Y. C.

“…Time to sustained worsening in the expanded disability status scale as the standard for evaluating the accumulation of disability has been used as a measure of…”
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Serum IL-17F does not predict poor response to IM IFN beta -1a in relapsing-remitting MS by Bushnell, SE, Zhao, Z, Stebbins, C C, Cadavid, D, Buko, A M, Whalley, E T, Davis, JA, Versage, E M, Richert, J R, Axtell, R C, Steinman, L, Medori, R

“…Objective: There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response…”
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Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment by Polman, C H, Reingold, S C, Barkhof, F, Calabresi, P A, Clanet, M, Cohen, J A, Cutter, G R, Freedman, M S, Kappos, L, Lublin, F D, McFarland, H F, Metz, L M, Miller, A E, Montalban, X, O'Connor, P W, Panitch, H, Richert, J R, Petkau, J, Schwid, S R, Sormani, M P, Thompson, A J, Weinshenker, B G, Wolinsky, J S

“…The increasing number of established effective therapies for relapsing multiple sclerosis (MS) and emerging consensus for early treatment raise practical…”
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A longitudinal study of brain atrophy in relapsing multiple sclerosis by SIMON, J. H, JACOBS, L. D, SIMONIAN, N, LAJAUNIE, M, MILLER, D. E, WENDE, K, MARTENS-DAVIDSON, A, KINKEL, R. P, MUNSCHAUER, F. E, BROWNSCHEIDLE, C. M, CAMPION, M. K, RUDICK, R. A, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, FISCHER, J. S, GOODKIN, D. E

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Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106 by Martin, R, Utz, U, Coligan, JE, Richert, JR, Flerlage, M, Robinson, E, Stone, R, Biddison, WE, McFarlin, DE, McFarland, HF

“…Multiple sclerosis (MS), a human demyelinating disease, is thought to be caused by an autoimmunologic process, and myelin basic protein (MBP) is considered a…”
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Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens by Jacobson, S, Richert, JR, Biddison, WE, Satinsky, A, Hartzman, RJ, McFarland, HF

“…We have generated measles virus-specific T cell clones from a patient with multiple sclerosis who has been described previously as a strong responder to…”
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A longitudinal study of T1 hypointense lesions in relapsing MS : MSCRG trial of interferon β-1a by SIMON, J. H, LULL, J, MCCABE, K, SERRA, A, CAMPION, M. K, FISCHER, J. S, GOODKIN, D. E, SIMONIAN, N, LAJAUNIE, M, WENDE, K, MARTENS-DAVIDSON, A, KINKEL, R. P, JACOBS, L. D, MUNSCHAUER, F. E, RUDICK, R. A, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, SHEEDER, J, MILLER, D

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Antigen Presentation to HLA Class II-Restricted Measles Virus-Specific T-Cell Clones Can Occur in the Absence of the Invariant Chain by Sekaly, Rafick P., Jacobson, Steven, Richert, John R., Tonnelle, Cecile, McFarland, Henry F., Long, Eric O.

“…A human fibroblast line expressing HLA-DR1 antigen on its surface was generated by transfection with DRα and DRβ cDNAs. Expression of the invariant chain gene…”
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Diversity of T-cell receptor Vα, Vβ, and CDR3 expression by myelin basic protein-specific human T-cell clones by RICHERT, J. R, ROBINSON, E. D, CAMPHAUSEN, K, MARTIN, R, VOSKUHL, R. R, FAERBER, M. A, MCFARLAND, H. F, HURLEY, C. K

“…We sequenced the cDNAs of alpha and beta T-cell receptors (TCRs), including V, J, and CDR3 regions, expressed by 54 myelin basic protein (MBP)-specific T-cell…”
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Open label gabapentin treatment for pain in multiple sclerosis by Houtchens, M K, Richert, J R, Sami, A, Rose, J W

“…Pain is a frequent and distressing complaint in patients with multiple sclerosis (MS) and may present a difficult therapeutic problem. Conventional therapy is…”
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A phase III trial of intramuscular recombinant interferon beta as treatment for exacerbating-remitting multiple sclerosis: design and conduct of study and baseline characteristics of patients. Multiple Sclerosis Collaborative Research Group (MSCRG) by Jacobs, L D, Cookfair, D L, Rudick, R A, Herndon, R M, Richert, J R, Salazar, A M, Fischer, J S, Goodkin, D E, Granger, C V, Simon, J H

“…The design and conduct of a randomized, double-blinded, placebo-controlled, multicenter, phase III study of recombinant interferon beta-1a (IFN-beta-1a) as…”
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Characterization of antigen-specific T cells in multiple sclerosis twins with elevated proliferative responses to measles virus by Greenstein, JI, McFarland, HF, Richert, JR

“…The proliferative response to measles virus in normal individuals is low compared with the response to mumps virus. This is probably due to a low precursor…”
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Polypeptide specificities of measles virus-reactive T cell lines and clones derived from a patient with multiple sclerosis by Richert, JR, Rose, JW, Reuben-Burnside, C, Kearns, MC, Jacobson, S, Mingioli, ES, Hartzman, RJ, McFarland, HF, McFarlin, DE

“…Eleven cloned and uncloned measles virus-specific T cell lines were generated from peripheral blood lymphocytes obtained from a patient with multiple sclerosis…”
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Cytomegalovirus encephalitis associated with episodic neurologic deficits and OKT-8+ pleocytosis by RICHERT, J. R, POTOLICCHIO, S. JR, GARAGUSI, V. F, MANZ, H. J, COHAN, S. L, HARTMANN, D. P, JOHNSON, R. T

“…After 3 days of symptoms suggesting a viral illness, a 35-year-old man experienced three episodes of aphasia, right-sided sensory symptoms, and bifrontal…”
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Measles-specific T cell clones derived from a twin with multiple sclerosis: genetic restriction studies by Richert, JR, McFarland, HF, McFarlin, DE, Johnson, AH, Woody, JN, Hartzman, RJ

“…The association between multiple sclerosis (MS) and HLA-DR2 suggests that the disease may be associated with an aberrant immune response, likely directed…”
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Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis: Multiple sclerosis by RUDICK, R. A, GOODKIN, D. E, ALAM, J. J, SIMONIAN, N. A, CAMPION, M. K, BARTOSZAK, D. M, BOURDETTE, D. N, BRAIMAN, J, BROWNSCHEIDLE, C. M, COATS, M. E, COHAN, S. L, DOUGHERTY, D. S, JACOBS, L. D, KINKEL, R. P, MASS, M. K, MUNSCHAUER, F. E, PRIORE, R. L, PULLICINO, P. M, SCHEROKMAN, B. J, WEISTOCK-GUTTMAN, B, WHITHAM, R. H, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, FISCHER, J. S, GRANGER, C. V, SIMON, J. H

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