Search Results - "Richerson, G. B."
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Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction
Published in Molecular psychiatry (01-10-2013)“…Autism spectrum disorders (ASDs) have been suggested to arise from abnormalities in the canonical and non-canonical Wnt signaling pathways. However, a direct…”
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Development of chemosensitivity of rat medullary raphe neurons
Published in Neuroscience (01-03-1999)“…In many neonatal mammals, including humans and rats, there is a developmental increase in the ventilatory response to elevated pCO 2. This maturation of…”
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Response to CO2 of neurons in the rostral ventral medulla in vitro
Published in Journal of neurophysiology (01-03-1995)“…1. It has been hypothesized that CO2-sensitive neurons are located in the rostral ventral medulla. To demonstrate this at the cellular level, perforated…”
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Homing in on the specific phenotype(s) of central respiratory chemoreceptors
Published in Experimental physiology (01-05-2005)“…To some it may seem that we now know less about respiratory chemoreception than we did 20 years ago. Back then, it was widely accepted that the central…”
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Origin of Variability in Quantal Size in Cultured Hippocampal Neurons and Hippocampal Slices
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-1990)“…The size of synaptic quanta has been found to display considerable variation in cultured hippocampal neurons, but the source of this variability was previously…”
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Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception
Published in Neuroscience (24-10-2014)“…Highlights • Pet1/DTR mice express diphtheria toxin receptors on serotonin neurons. • Systemic diphtheria toxin causes loss of 80% of serotonin neurons. •…”
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Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli
Published in Genes, brain and behavior (01-02-2014)“…Acid‐sensing ion channels (ASICs) generate H+‐gated Na+ currents that contribute to neuronal function and animal behavior. Like ASIC1, ASIC2 subunits are…”
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Dynamic Equilibrium of Neurotransmitter Transporters: Not Just for Reuptake Anymore
Published in Journal of neurophysiology (01-09-2003)“…Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven 06520 and Veteran's Affairs Medical Center, West…”
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Chemosensitivity of non-respiratory rat CNS neurons in tissue culture
Published in Brain research (31-03-2000)“…Neurons from many brainstem nuclei involved in respiratory control increase their firing rate in response to acidosis in vitro, suggesting that they are…”
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Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro
Published in Epilepsy research (01-03-1995)“…The anticonvulsant gabapentin (1-(aminomethyl)cyclohexane acetic acid) has been found to be effective for treatment of partial seizures, but the mechanism of…”
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Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction
Published in Molecular psychiatry (01-06-2014)Get full text
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12
Effect of composition of experimental solutions on neuronal survival during rat brain slicing
Published in Experimental neurology (1995)“…Brain slices are widely used for experimentation; however, preparing brain slices results in significant injury as a result of a combination of ischemia prior…”
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Vigabatrin Induces Tonic Inhibition Via GABA Transporter Reversal Without Increasing Vesicular GABA Release
Published in Journal of neurophysiology (01-04-2003)“… 1 Departments of Neurology, and 2 Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520; and 3 Veteran's…”
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Re: Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors
Published in Experimental physiology (01-05-2005)Get full text
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GABA Transaminase Inhibition Induces Spontaneous and Enhances Depolarization-Evoked GABA Efflux via Reversal of the GABA Transporter
Published in The Journal of neuroscience (15-04-2001)“…The GABA transporter can reverse with depolarization, causing nonvesicular GABA release. However, this is thought to occur only under pathological conditions…”
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Chemosensitive serotonergic neurons are closely associated with large medullary arteries
Published in Nature neuroscience (01-05-2002)“…We have previously shown that serotonergic neurons of the medulla are strongly stimulated by an increase in CO2, suggesting that they are central respiratory…”
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Acidosis-Stimulated Neurons of the Medullary Raphe Are Serotonergic
Published in Journal of neurophysiology (01-05-2001)“… 1 Departments of Neurology and Cellular and Molecular Physiology, Yale University, New Haven 06510; and 2 Veteran's Affairs Medical Center, West Haven,…”
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Re: Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors
Published in Experimental physiology (01-05-2005)Get full text
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Chemosensitivity of rat medullary raphe neurones in primary tissue culture
Published in The Journal of physiology (01-09-1998)“…The medullary raphe, within the ventromedial medulla (VMM), contains putative central respiratory chemoreceptors. To study the mechanisms of chemosensitivity…”
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Thyrotropin-Releasing Hormone Induces Rhythmic Bursting in Neurons of the Nucleus Tractus Solitarius
Published in Science (American Association for the Advancement of Science) (05-07-1985)“…The nucleus tractus solitarius (NTS) contains neurons that are part of the central neuronal network controlling rhythmic breathing movements in mammals. Nerve…”
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