Search Results - "Richele P. Severino"

Evaluation of synthetic acridones and 4-quinolinones as potent inhibitors of cathepsins L and V by Marques, Emerson F., Bueno, Mauro A., Duarte, Patrícia D., Silva, Larissa R.S.P., Martinelli, Ariani M., dos Santos, Caio Y., Severino, Richele P., Brömme, Dieter, Vieira, Paulo C., Corrêa, Arlene G.

“…Cathepsins, also known as lysosomal cysteine peptidases, are members of the papain-like peptidase family, involved in different physiological processes. In…”
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Salvia miltiorrhiza: An ancient Chinese herbal medicine as a source for anti-osteoporotic drugs by Guo, Yubo, Li, Yu, Xue, Liming, Severino, Richele P., Gao, Sihua, Niu, Jianzhao, Qin, Lu-Ping, Zhang, Dongwei, Brömme, Dieter

“…Red sage (Salvia miltiorrhiza Bunge), also known as Danshen in Chinese, has been used historically and is currently exploited in combination with other herbs…”
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Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi by Pereira, Junia M., Severino, Richele P., Vieira, Paulo C., Fernandes, João B., da Silva, M. Fátima G.F., Zottis, Aderson, Andricopulo, Adriano D., Oliva, Glaucius, Corrêa, Arlene G.

“…In this work, we describe the inhibitory effects of a small library of natural and synthetic anacardic acid derivatives against the enzyme…”
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Phosphoenolpyruvate carboxykinase from T. cruzi magnetic beads affinity-based screening assays on crude plant extracts from Brazilian Cerrado by do Amaral, Bruno S., da Silva, Larissa R.G., Valverde, Alessandra L., de Sousa, Lorena R.F., Severino, Richele P., de Souza, Dulce H.F., Cass, Quezia B.

“…[Display omitted] •Cerrado Brazilian plants ethanolic extract as natural products library.•High specificity affinity-based assay for PEPCK.•Eleven ligands…”
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Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents by Mendes, Léia da C., Dantas, Thais B. Vieira, Severino, Richele P., da Silva, Larissa Ramos G., de Souza, Dulce H. F., Cass, Quezia B., Ramalho, Suelem D., Vieira, Paulo C., de Souza, Guilherme E., Guido, Rafael V. C., Urschel, Marie-Kathrin, Kersten, Christian, de Sousa, Lorena R. F.

“…Arginase is a potential target of drugs against Leishmania spp. Natural products can be a source of arginase inhibitors. This study has investigated whether…”
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Structure and Absolute Configuration of Diterpenoids from Hymenaea stigonocarpa by Monteiro, Afif F, Batista, João M, Machado, Michelle A, Severino, Richele P, Blanch, Ewan W, Bolzani, Vanderlan S, Vieira, Paulo C, Severino, Vanessa G. P

“…Chemical investigations of the ethanolic extracts from the flowers and leaves of Hymenaea stigonocarpa Mart. ex Hayne afforded one new ent-halimane…”
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Syntheses of enantiopure aliphatic secondary alcohols and acetates by bioresolution with lipase B from Candida antarctica by Ferreira, Hercules V, Rocha, Lenilson C, Severino, Richele P, Porto, André L M

“…The lipase B from Candida antarctica (Novozym 435®, CALB) efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols:…”
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NEW DEGRADED QUINONE DITERPENOID FROM THE STEMS OF Byrsonima coccolobifolia Kunth. (Malpighiaceae) by Sousa, Lorena, Santos, Marcos, Severino, Vanessa, Severino, Richele, Vieira, Paulo

“…A chemical investigation of two specimens of Byrsonima coccolobifolia collected in the southeast cerrado and from central Brazil was performed. A new degraded…”
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Acridone alkaloids as potent inhibitors of cathepsin V by Severino, Richele P., Guido, Rafael V.C., Marques, Emerson F., Brömme, Dieter, da Silva, M. Fátima das G.F., Fernandes, João B., Andricopulo, Adriano D., Vieira, Paulo C.

“…In this work, we describe the inhibitory effects of acridone alkaloids isolated from Swinglea glutinosa a plant belonging to the Rutaceae family. This class of…”
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ALCALOIDES ACRIDÔNICOS INIBEM CATEPSINA L E V by Emerson F. Marques, Paulo C. Vieira, Richele P. Severino

“…Cathepsins represent a class of enzymes that has the primary function of randomly degrading proteins in the lysosomes, although are also involved in different…”
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ACRIDONE ALKALOIDS AS INHIBITORS OF CATHEPSIN L AND V by Marques, Emerson F., Vieira, Paulo C., Severino, Richele P.

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Chemical Prospection of Qualea grandiflora Mart. Fruit and Stem Extracts and Their in vitro and in vivo Antiplasmodial Activity by Gonçalves Neto, Geraldo, da Costa, Romário, Zanini, Camila, Aguiar, Anna Caroline, de Souza, Juliana, de Souza, Guilherme, Severino, Richele, Cass, Quezia, Cruz, Fábio, Oliva, Glaucius, Guido, Rafael, de Sousa, Lorena

“…Qualea grandiflora Mart. (“pau-terra”) is a medicinal plant symbolic from Cerrado biome. Qualea species reportedly have antiparasitic properties, but their…”
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Solution Phase Synthesis of a Combinatorial Library of Chalcones and Flavones as Potent Cathepsin V Inhibitors by Alvim, Joel, Severino, Richele P, Marques, Emerson F, Martinelli, Ariane M, Vieira, Paulo C, Fernandes, João B, da Silva, M. Fatima das G. F, Corrêa, Arlene G

“…Cathepsin V is a papain-like cysteine protease. It is involved in the control of human T cells (responsible for cell immunity), and presents the largest…”
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Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from em>Candida antarctica /em by Richele P. Severino, Hercules V. Ferreira, André L. M. Porto, Lenilson C. Rocha

“…The lipase B from Candida antarctica (Novozym 435 ® , CALB) efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols:…”
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