Search Results - "Richardson, Magnus J. E"

Experimentally Verified Parameter Sets for Modelling Heterogeneous Neocortical Pyramidal-Cell Populations by Harrison, Paul M, Badel, Laurent, Wall, Mark J, Richardson, Magnus J E

“…Models of neocortical networks are increasingly including the diversity of excitatory and inhibitory neuronal classes. Significant variability in cellular…”
Get full text

Transmission of temporally correlated spike trains through synapses with short-term depression by Bird, Alex D, Richardson, Magnus J E

“…Short-term synaptic depression, caused by depletion of releasable neurotransmitter, modulates the strength of neuronal connections in a history-dependent…”
Get full text

Dynamic I-V Curves Are Reliable Predictors of Naturalistic Pyramidal-Neuron Voltage Traces by Badel, Laurent, Lefort, Sandrine, Brette, Romain, Petersen, Carl C. H, Gerstner, Wulfram, Richardson, Magnus J. E

“…1 Laboratory of Computational Neuroscience, School of Computer and Communication Sciences and Brain Mind Institute and 2 Laboratory of Sensory Processing,…”
Get full text

Spike-train spectra and network response functions for non-linear integrate-and-fire neurons by Richardson, Magnus J. E.

“…Reduced models have long been used as a tool for the analysis of the complex activity taking place in neurons and their coupled networks. Recent advances in…”
Get full text

From Subthreshold to Firing-Rate Resonance by Richardson, Magnus J. E, Brunel, Nicolas, Hakim, Vincent

“…  1 Laboratoire de Physique Statistique, Ecole Normale Supérieure, 75231 Paris Cedex 05, France;   2 Laboratory of Computational Neuroscience, Brain and Mind…”
Get full text

Extracting non-linear integrate-and-fire models from experimental data using dynamic I-V curves by Badel, Laurent, Lefort, Sandrine, Berger, Thomas K, Petersen, Carl C. H, Gerstner, Wulfram, Richardson, Magnus J. E

“…The dynamic I-V curve method was recently introduced for the efficient experimental generation of reduced neuron models. The method extracts the response…”
Get full text

Matched pre- and post-synaptic changes underlie synaptic plasticity over long time scales by Loebel, Alex, Le Bé, Jean-Vincent, Richardson, Magnus J E, Markram, Henry, Herz, Andreas V M

“…Modifications of synaptic efficacies are considered essential for learning and memory. However, it is not known how the underlying functional components of…”
Get full text

The dynamics of single spike‐evoked adenosine release in the cerebellum by Klyuch, Boris P., Richardson, Magnus J. E., Dale, Nicholas, Wall, Mark J.

“…Non‐technical summary Adenosine modulates brain activity in both health and disease. Although we know a lot about adenosine action, we know little about how it…”
Get full text

Single neuron dynamics and computation by Brunel, Nicolas, Hakim, Vincent, Richardson, Magnus JE

“…Highlights • LNP models provide a precise description of the static and dynamic responses of neurons. • Dynamic responses depend on neuron electrophysiological…”
Get full text

Measurement and Analysis of Postsynaptic Potentials Using a Novel Voltage-Deconvolution Method by Richardson, Magnus J. E, Silberberg, Gilad

“…1 Warwick Systems Biology Centre, University of Warwick, Coventry, United Kingdom; and 2 Department of Neuroscience, Nobel Institute for Neurophysiology,…”
Get full text

Low-rate firing limit for neurons with axon, soma and dendrites driven by spatially distributed stochastic synapses by Gowers, Robert P, Timofeeva, Yulia, Richardson, Magnus J E

“…Analytical forms for neuronal firing rates are important theoretical tools for the analysis of network states. Since the 1960s, the majority of approaches have…”
Get full text

Intracellular soluble α‐synuclein oligomers reduce pyramidal cell excitability by Kaufmann, Timothy J., Harrison, Paul M., Richardson, Magnus J. E., Pinheiro, Teresa J. T., Wall, Mark J.

“…Key points The presynaptic protein α‐synuclein forms aggregates during Parkinson's disease. Accumulating evidence suggests that the small soluble oligomers of…”
Get full text

Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength by Kerr, Michael I., Wall, Mark J., Richardson, Magnus J. E.

“…Key points •  Neocortical layer 5 pyramidal cell synapses exhibit a developmental reduction in neurotransmitter release probability. Mature synapses are…”
Get full text

Localized adenosine signaling provides fine-tuned negative feedback over a wide dynamic range of neocortical network activities by Wall, Mark J, Richardson, Magnus J E

“…Although the patterns of activity produced by neocortical networks are now better understood, how these states are activated, sustained, and terminated still…”
Get full text

Reducing Extracellular Ca2+ Induces Adenosine Release via Equilibrative Nucleoside Transporters to Provide Negative Feedback Control of Activity in the Hippocampus by Diez, Rebecca, Richardson, Magnus J. E., Wall, Mark J.

“…Neural circuit activity increases the release of the purine neuromodulator adenosine into the extracellular space leading to A1 receptor activation and…”
Get full text

Comparing Smooth Arm Movements with the Two-Thirds Power Law and the Related Segmented-Control Hypothesis by Richardson, Magnus J. E, Flash, Tamar

“…The movements of the human arm have been extensively studied for a variety of goal-directed experimental tasks. Analyses of the trajectory and velocity of the…”
Get full text

Bayesian Inference of Synaptic Quantal Parameters from Correlated Vesicle Release by Bird, Alex D, Wall, Mark J, Richardson, Magnus J E

“…Synaptic transmission is both history-dependent and stochastic, resulting in varying responses to presentations of the same presynaptic stimulus. This…”
Get full text

Single-cell mechanics and calcium signalling in organotypic slices of human myometrium by Loftus, Fiona C, Richardson, Magnus J.E, Shmygol, Anatoly

“…Abstract Elucidation of cellular mechanisms regulating myometrial contractility is crucial for improvement in management of many obstetric abnormalities, such…”
Get full text

Fine spatiotemporal activity in contracting myometrium revealed by motion‐corrected calcium imaging by Loftus, Fiona C., Shmygol, Anatoly, Richardson, Magnus J. E.

“…Key points Calcium indicator fluorescence imaging is a key tool for investigating the physiological mechanisms that initiate and regulate myometrial…”
Get full text

Long-term plasticity determines the postsynaptic response to correlated afferents with multivesicular short-term synaptic depression by Bird, Alex D, Richardson, Magnus J E

“…Synchrony in a presynaptic population leads to correlations in vesicle occupancy at the active sites for neurotransmitter release. The number of independent…”
Get full text