Search Results - "Richardson, Darcy M."

Mechanisms of aging-induced impairment of endothelium-dependent relaxation: role of tetrahydrobiopterin by Blackwell, Katherine A, Sorenson, Joseph P, Richardson, Darcy M, Smith, Leslie A, Suda, Osamu, Nath, Karl, Katusic, Zvonimir S

“…Oxidative stress has been implicated as an important mechanism of vascular endothelial dysfunction induced by aging. Previous studies suggested that…”
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Development of a flipped learning course to deliver and scale molecular variant evaluation education: A quality improvement initiative by Balcom, Jessica R., Ellingson, Marissa S., Bowler, Carrie A., Richardson, Darcy M., Kruisselbrink, Teresa, Thomas, Brittany C.

“…Over the past several decades, molecular genetic testing volumes have grown and testing has expanded from single‐gene assays to multigene panels, exome…”
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Implementation of a pharmacogenomics education program for pharmacists by Formea, Christine M, Nicholson, Wayne T, Vitek, Carolyn Rohrer, Wix, Kelly K, McCullough, Kristen B, Cunningham, Julie L, Zeuli, John D, Matey, Eric T, Merten, Julianna A, Richardson, Darcy M, Billings, Andrea L, Schramm, Garrett E

“…PURPOSE.The development, implementation, and evaluation of a pharmacogenomics education program for pharmacists in a large, integrated multicampus health…”
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Insulin and Insulin-like Growth Factor-I Cause Coronary Vasorelaxation In Vitro by Hasdai, David, Rizza, Robert A, Holmes, David R, Richardson, Darcy M, Cohen, Pinchas, Lerman, Amir

“…Insulin and insulin-like growth factor-I (IGF-I) may play a role in the modulation of coronary artery tone, yet there are few data regarding their vasoactive…”
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Insulin and insulin-like growth factor-I cause vasorelaxation in human vessels in vitro by Izhar, Uzi, Hasdai, David, Richardson, Darcy M, Cohen, Pinchas, Lerman, Amir

“…BACKGROUNDInsulin and insulin-like growth factor-I (IGF-I) are endogenous peptides with vasoactive activities. OBJECTIVETo evaluate the vasodilatory effects of…”
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Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin by Lam, Chen-Fuh, Peterson, Timothy E, Richardson, Darcy M, Croatt, Anthony J, d'Uscio, Livius V, Nath, Karl A, Katusic, Zvonimir S

“…Shear stress, imposed on the vascular endothelium by circulating blood, critically sustains vascular synthesis of nitric oxide (NO). Endothelial NO synthase…”
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Heart failure increases protein expression and enzymatic activity of heme oxygenase-1 in the lung by LAM, Chen F, CROATT, Anthony J, RICHARDSON, Darcy M, NATH, Karl A, KATUSIC, Zvonimir S

“…Heart failure (HF) cell or siderophages are pulmonary macrophages that phagonicytize erythrocytes leaked from the congested capillaries due to HF. Degradation…”
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In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery by Hynes, Sean O, Smith, Leslie A, Richardson, Darcy M, Kovesdi, Imre, O'Brien, Timothy, Katusic, Zvonimir S

“…Tetrahydrobiopterin (BH4) is an essential co-factor for endothelial nitric oxide synthase enzymatic activity. GTP cyclohydrolase I (GTPCH I) is the…”
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Genetic risk factors in inflammatory abdominal aortic aneurysms: Polymorphic residue 70 in the HLA-DR B1 gene as a key genetic element by Rasmussen, Todd E, Hallett, John W., Mathieu Metzger, Renate L., Richardson, Darcy M., Harmsen, William S., Goronzy, Jorg J., Weyand, Cornelia M.

“…Purpose: Evidence of a genetic predisposition to the development of inflammatory abdominal aortic aneurysms (AAAs) exists as a positive family history in 17%…”
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Implementation of preemptive DNA sequence–based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study by Wang, Liewei, Scherer, Steven E., Bielinski, Suzette J., Muzny, Donna M., Jones, Leila A., Black, John Logan, Moyer, Ann M., Giri, Jyothsna, Sharp, Richard R., Matey, Eric T., Wright, Jessica A., Oyen, Lance J., Wiepert, Mathieu, Sullard, Terri, Curry, Timothy B., Rohrer Vitek, Carolyn R., St. Sauver, Jennifer L., Lazaridis, Konstantinos N., Venner, Eric, Qin, Xiang, Kovar, Christie L., Korchina, Viktoriya, Walker, Kimberly, Doddapaneni, HarshaVardhan, Wu, Tsung-Jung, Raj, Ritika, Denson, Shawn, Chandanavelli, Gauthami, Zhang, Lan, Karow, Mary Beth, Harris, Kimberley J., Sicotte, Hugues, Peterson, Sandra E., Barthel, Amy E., Skierka, Jennifer M., Kluge, Michelle L., Kotzer, Katrina E., Kloke, Karen, Vander Pol, Jessica M., Sutton, Joseph A., Kekic, Adrijana, Ebenhoh, Ashley, Bierle, Dennis M., Schuh, Michael J., Grilli, Christopher, Erickson, Sara, Umbreit, Audrey, Ward, Leah, Nelson, Eric A., Levey, Sharon, Elliott, Michelle, Peters, Steve G., Pereira, Naveen, Frye, Mark, Shamoun, Fadi, Goetz, Matthew P., Kullo, Iftikhar J., Wermers, Robert, Anderson, Jan A., Formea, Christine M., El Melik, Razan M., Herges, Joseph R., Krieger, Carrie A., Hoel, Robert W., Taraba, Jodi L., St. Thomas, Scott R., Absah, Imad, Bernard, Matthew E., Fink, Stephanie R., Gossard, Andrea, Grubbs, Pamela L., Jacobson, Therese M., Takahashi, Paul, Buckles, Susan, Bumgardner, Michelle, Gallagher, Colette, Fee-Schroeder, Kelliann, Nicholas, Nichole R., Powers, Melody L., Ragab, Ahmed K., Richardson, Darcy M., Stai, Anthony, Olson, Janet E., Sutton, Erica J., Beck, Annika T., Horrow, Caroline, Kalari, Krishna R., Liu, Hongfang, Wang, Liwei, Zhu, Ye, Jacobson, Debra J., Hathcock, Matthew A., McGree, Michaela E., Koep, Tyler H., Ross, Jason L., Ramey, Bronwyn, Searcy, Isabelle, Boerwinkle, Eric, Gibbs, Richard A., Weinshilboum, Richard M.

“…The Mayo-Baylor RIGHT 10K Study enabled preemptive, sequence-based pharmacogenomics (PGx)-driven drug prescribing practices in routine clinical care within a…”
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Attenuated In Vitro Coronary Arteriolar Vasorelaxation to Insulin-like Growth Factor I in Experimental Hypercholesterolemia by Hasdai, David, Nielsen, Michael F, Rizza, Robert A, Holmes, David R, Richardson, Darcy M, Cohen, Pinchas, Lerman, Amir

“…Insulin and insulin-like growth factor (IGF) 1 affect coronary vasoactivity. Experimental hypercholesterolemia is associated with coronary atherogenesis and…”
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Coronary vasa vasorum neovascularization precedes epicardial endothelial dysfunction in experimental hypercholesterolemia by Herrmann, J, Lerman, L O, Rodriguez-Porcel, M, Holmes, Jr, D R, Richardson, D M, Ritman, E L, Lerman, A

“…Experimental hypercholesterolemia is associated with vasa vasorum neovascularization, unknown to occur before or after initial lesion formation. Thus, this…”
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Insulin and IGF-I attenuate the coronary vasoconstrictor effects of endothelin-1 but not of sarafotoxin 6c by HASDAI, D, HOLMES, D. R, RICHARDSON, D. M, IZHAR, U, LERMAN, A

“…To examine the hypothesis that insulin and insulin-like growth factor I (IGF-I) attenuate endothelin-induced contraction of porcine coronary epicardial…”
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Coronary vasa vasorum neovascularization precedes epicardial endothelial dysfunction in experimental hypercholesterolemia by HERRMANN, Joerg, LERMAN, Lilach O, RODRIGUEZ-PORCEL, Martin, HOLMES, David R, RICHARDSON, Darcy M, RITMAN, Erik L, LERMAN, Amir

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