Search Results - "Richards, James A"
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T cell Allorecognition Pathways in Solid Organ Transplantation
Published in Frontiers in immunology (05-11-2018)“…Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct pathways: as intact MHC alloantigen on the surface of donor cells…”
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Interactions between interfaces dictate stimuli-responsive emulsion behaviour
Published in Nature communications (23-10-2023)“…Stimuli-responsive emulsions offer a dual advantage, combining long-term storage with controlled release triggered by external cues such as pH or temperature…”
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Acute Liver Injury Is Independent of B Cells or Immunoglobulin M
Published in PloS one (25-09-2015)“…Acute liver injury is a clinically important pathology and results in the release of Danger Associated Molecular Patterns, which initiate an immune response…”
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Survival advantage for patients accepting the offer of a circulatory death liver transplant
Published in Journal of hepatology (01-05-2019)“…[Display omitted] •Outcomes for DCD are inferior to DBD liver transplantation in the UK experience.•There is a survival advantage in accepting a DCD offer…”
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Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD
Published in Wellcome open research (2017)“…: Non-alcoholic fatty liver disease (NAFLD) is a global health issue. Dietary methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis…”
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Ischemic preconditioning in the liver is independent of regulatory T cell activity
Published in PloS one (21-11-2012)“…Ischemic preconditioning (IPC) protects organs from ischemia reperfusion injury (IRI) through unknown mechanisms. Effector T cell populations have been…”
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Turning a yield-stress calcite suspension into a shear-thickening one by tuning inter-particle friction
Published in Rheologica acta (01-03-2021)“…We show that a suspension of non-Brownian calcite particles in glycerol-water mixtures can be tuned continuously from being a yield-stress suspension to a…”
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Optimizing non-Newtonian fluids for impact protection of laminates
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2024)“…Non-Newtonian fluids can be used for the protection of flexible laminates. Understanding the coupling between the flow of the protecting fluid and the…”
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Outcomes of livers from donation after circulatory death donors with extended agonal phase and the adjunct of normothermic regional perfusion
Published in British journal of surgery (11-08-2023)“…The liver performs important functions that are essential for life. If the liver fails, patients will die unless they receive a new liver from a donor…”
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Heme oxygenase system in hepatic ischemia-reperfusion injury
Published in World journal of gastroenterology : WJG (2010)Get full text
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To NRP or Not to NRP, That Is the Question
Published in Transplantation (01-12-2019)Get full text
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Machine Perfusion—Leaving Its Mark on Liver Transplantation
Published in Transplantation (01-02-2021)Get full text
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Model for early allograft function is predictive of early graft loss in donation after circulatory death liver transplantation
Published in Clinical transplantation (01-08-2020)“…Donation after circulatory death (DCD) liver transplantation is associated with higher rates of graft loss. In this paper, we explored whether the Model for…”
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The 6 C's of Normothermic Regional Perfusion
Published in Progress in transplantation (Aliso Viejo, Calif.) (01-06-2022)Get full text
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Granulocyte macrophage-colony stimulating factor: A key modulator of renal mononuclear phagocyte plasticity
Published in Immunobiology (1979) (01-01-2019)“…Macrophage-colony stimulating factor (M-CSF) and granulocyte macrophage-colony stimulating factor (GM-CSF) play key roles in the differentiation of macrophages…”
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NKT cells are important mediators of hepatic ischemia-reperfusion injury
Published in Transplant immunology (01-12-2017)“…IRI results from the interruption then reinstatement of an organ's blood supply, and this poses a significant problem in liver transplantation and resectional…”
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Heme oxygenase system in hepatic ischemia-reperfusion injury
Published in World journal of gastroenterology : WJG (28-12-2010)“…Hepatic ischemia-reperfusion injury (IRI) limits access to transplantation. Heme oxygenase-1 (HO-1) is a powerful antioxidant enzyme which degrades free heme…”
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Fresh cement as a frictional non-Brownian suspension
Published in Powder technology (15-05-2024)“…Cement is an essential construction material due to its ability to flow before later setting, however the rheological properties must be tightly controlled…”
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