Search Results - "Richards, Anna"
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The relationship between glucocerebrosidase mutations and Parkinson disease
Published in Journal of neurochemistry (01-10-2016)“…Parkinson disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease, whereas Gaucher disease (GD) is the most frequent…”
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Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice
Published in Annals of neurology (01-11-2016)“…Objective Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase. Both…”
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Atypical Hemolytic Uremic Syndrome
Published in Seminars in nephrology (01-11-2013)“…Summary Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is…”
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L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
Published in PloS one (24-08-2020)“…Parkinson disease is the most common neurodegenerative movement disorder, estimated to affect one in twenty-five individuals over the age of 80. Mutations in…”
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Immersive landscapes: modelling ecosystem reference conditions in virtual reality
Published in Landscape ecology (01-05-2022)“…Context Understanding the variability and dynamics of ecosystems, as well as their responses to climate or land use change, is challenging for policy makers…”
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Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate
Published in Synapse (New York, N.Y.) (01-07-2017)“…Mutations in the glucocerebrosidase 1 (GBA1) gene are related to both Parkinson disease (PD) and Gaucher disease (GD). In both cases, the condition is…”
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STAT3 Signaling in Breast Cancer: Multicellular Actions and Therapeutic Potential
Published in Cancers (15-01-2022)“…Interleukin (IL)-6 family cytokines, such as IL-6 and IL-11, are defined by the shared use of the gp130 receptor for the downstream activation of STAT3…”
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Socioeconomic factors associated with uptake and satisfaction with a post‐hospitalization meals benefit in Medicare Advantage
Published in Journal of the American Geriatrics Society (JAGS) (01-08-2024)“…Background Kaiser Permanente Southern California began offering a 4‐week supplemental benefit of home‐delivered meals to Medicare Advantage members after…”
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Effects of plant hydraulic traits on the flammability of live fine canopy fuels
Published in Functional ecology (01-04-2021)“…Plant species vary in how they regulate moisture and this has implications for their flammability during wildfires. We explored how fuel moisture is shaped by…”
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The influence of mixed tree plantations on the nutrition of individual species: a review
Published in Tree physiology (01-09-2010)“…Productivity of tree plantations is a function of the supply, capture and efficiency of use of resources, as outlined in the Production Ecology Equation…”
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An Overview of Epigenetic Changes in the Parkinson's Disease Brain
Published in International journal of molecular sciences (01-06-2024)“…Parkinson's disease is a progressive neurodegenerative disorder, predominantly of the motor system. Although some genetic components and cellular mechanisms of…”
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relationship between stem biomechanics and wood density is modified by rainfall in 32 Australian woody plant species
Published in The New phytologist (01-01-2010)“…Stem mechanical properties are critically linked to foliage deployment and growth strategy, yet variation in stem mechanics across species and habitats is…”
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Climate and soils together regulate photosynthetic carbon isotope discrimination within C3 plants worldwide
Published in Global ecology and biogeography (01-09-2018)“…AimWithin C3 plants, photosynthesis is a balance between CO2 supply from the atmosphere via stomata and demand by enzymes within chloroplasts. This process is…”
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Fire regime shapes butterfly communities through changes in nectar resources in an Australian tropical savanna
Published in Ecosphere (Washington, D.C) (01-11-2023)“…Fire‐dependent savanna provides key habitat for butterflies globally, but we know little about how fire regimes, including fire frequency and season, affect…”
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Nitrogen but not phosphorus addition affects symbiotic N2 fixation by legumes in natural and semi-natural grasslands located on four continents
Published in Plant and soil (01-09-2022)“…Background and aims The amount of nitrogen (N) derived from symbiotic N 2 fixation by legumes in grasslands might be affected by anthropogenic N and phosphorus…”
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Sapwood capacitance is greater in evergreen sclerophyll species growing in high compared to low‐rainfall environments
Published in Functional ecology (01-06-2014)“…The capacitative release of water from sapwood allows photosynthesis to continue for longer into dry periods, both diurnally and seasonally. However, costs of…”
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A globally relevant change taxonomy and evidence‐based change framework for land monitoring
Published in Global change biology (01-11-2022)“…A globally relevant and standardized taxonomy and framework for consistently describing land cover change based on evidence is presented, which makes use of…”
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A systematic review of eculizumab for atypical haemolytic uraemic syndrome (aHUS)
Published in BMJ open (04-11-2013)“…Objective To determine the efficacy and safety of eculizumab for patients with atypical haemolytic uraemic syndrome (aHUS), compared with current treatment…”
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Rapid response of habitat structure and above-ground carbon storage to altered fire regimes in tropical savanna
Published in Biogeosciences (10-04-2019)“…Fire regimes across the globe have been altered through changes in land use, land management, and climate conditions. Understanding how these modified fire…”
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Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface–selective regulation of complement activation
Published in The Journal of biological chemistry (11-08-2017)“…Spontaneous activation enables the complement system to respond very rapidly to diverse threats. This activation is efficiently suppressed by complement factor…”
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