Search Results - "Richard Breathnach"

The Juxtamembrane Domain of Butyrophilin BTN3A1 Controls Phosphoantigen-Mediated Activation of Human Vγ9Vδ2 T Cells by Peigné, Cassie-Marie, Léger, Alexandra, Gesnel, Marie-Claude, Konczak, Fabienne, Olive, Daniel, Bonneville, Marc, Breathnach, Richard, Scotet, Emmanuel

“…Vγ9Vδ2 T lymphocytes are the major human peripheral γδ T cell subset, with broad reactivity against stressed human cells, including tumor cells. Vγ9Vδ2 T cells…”
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Ex vivo evolution of human antibodies by CRISPR-X: from a naive B cell repertoire to affinity matured antibodies by Devilder, Marie-Claire, Moyon, Melinda, Gautreau-Rolland, Laetitia, Navet, Benjamin, Perroteau, Jeanne, Delbos, Florent, Gesnel, Marie-Claude, Breathnach, Richard, Saulquin, Xavier

“…Keywords: Human antibodies, SHM, CRISPR, CRISPR-X, AID, Tetramers, HLA, Cytofluorimetry…”
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hnRNP A1 Recruited to an Exon In Vivo Can Function as an Exon Splicing Silencer by Del Gatto-Konczak, Fabienne, Olive, Michelle, Gesnel, Marie-Claude, Breathnach, Richard

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The RNA-Binding Protein TIA-1 Is a Novel Mammalian Splicing Regulator Acting through Intron Sequences Adjacent to a 5′ Splice Site by Del Gatto-Konczak, Fabienne, Bourgeois, Cyril F., Le Guiner, Caroline, Kister, Liliane, Gesnel, Marie-Claude, Stévenin, James, Breathnach, Richard

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The CD44 Alternative v9 Exon Contains a Splicing Enhancer Responsive to the SR Proteins 9G8, ASF/SF2, and SRp20 by Galiana-Arnoux, Delphine, Lejeune, Fabrice, Gesnel, Marie-Claude, Stevenin, James, Breathnach, Richard, Del Gatto-Konczak, Fabienne

“…The CD44 gene alternative exons v8, v9, and v10 are frequently spliced as a block by epithelial cells. By transfecting minigenes containing only one of these…”
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TIA-1 or TIAR Is Required for DT40 Cell Viability by Le Guiner, Caroline, Gesnel, Marie-Claude, Breathnach, Richard

“…TIA-1 and TIAR are a pair of related RNA-binding proteins which have been implicated in apoptosis. We show that chicken DT40 cells with both tia-1 alleles and…”
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Epidermal growth factor stimulates transcription of the c- jun proto-oncogene in rat fibroblasts by Quantin, Béatrice, Breathnach, Richard

“…Some growth factor-induced genes, such as the c-fos gene, are activated rapidly and transiently without intervening protein synthesis. Others, like the rat…”
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TIA Proteins Are Necessary but Not Sufficient for the Tissue-specific Splicing of the Myosin Phosphatase Targeting Subunit 1 by Shukla, S, Dirksen, W P, Joyce, K M, Le Guiner-Blanvillain, C, Breathnach, R, Fisher, SA

“…We are using the tissue-specific splicing of myosin phosphatase targeting subunit (MYPT1) as a model to investigate smooth muscle phenotypic diversity. We…”
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The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V gamma 9V delta 2 T Cells by Sandstrom, Andrew, Peigne, Cassie-Marie, Leger, Alexandra, Crooks, James E, Konczak, Fabienne, Gesnel, Marie-Claude, Breathnach, Richard, Bonneville, Marc, Scotet, Emmanuel, Adams, Erin J

“…In humans, V gamma 9V delta 2 T cells detect tumor cells and microbial infections, including , through recognition of small pyrophosphate containing organic…”
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The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells by Sandstrom, Andrew, Peigné, Cassie-Marie, Léger, Alexandra, Crooks, James E., Konczak, Fabienne, Gesnel, Marie-Claude, Breathnach, Richard, Bonneville, Marc, Scotet, Emmanuel, Adams, Erin J.

“…In humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, including Mycobacterium tuberculosis, through recognition of small pyrophosphate…”
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Polypyrimidine Tract-binding Protein Represses Splicing of a Fibroblast Growth Factor Receptor-2 Gene Alternative Exon through Exon Sequences by Le Guiner, Caroline, Plet, Ariane, Galiana, Delphine, Gesnel, Marie-Claude, Del Gatto-Konczak, Fabienne, Breathnach, Richard

“…The fibroblast growth factor receptor (FGFR)-2 gene contains two mutually exclusive exons, K-SAM and BEK. We made a cell line designed to become drug-resistant…”
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Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset by Harly, Christelle, Guillaume, Yves, Nedellec, Steven, Peigné, Cassie-Marie, Mönkkönen, Hannu, Mönkkönen, Jukka, Li, Jianqiang, Kuball, Jürgen, Adams, Erin J., Netzer, Sonia, Déchanet-Merville, Julie, Léger, Alexandra, Herrmann, Thomas, Breathnach, Richard, Olive, Daniel, Bonneville, Marc, Scotet, Emmanuel

“…Human peripheral Vγ9Vδ2 T cells are activated by phosphorylated metabolites (phosphoagonists [PAg]) of the mammalian mevalonate or the microbial…”
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The Juxtamembrane Domain of Butyrophilin BTN3A1 Controls Phosphoantigen-Mediated Activation of Human V gamma 9V delta 2 T Cells by Peigne, Cassie-Marie, Leger, Alexandra, Gesnel, Marie-Claude, Konczak, Fabienne, Olive, Daniel, Bonneville, Marc, Breathnach, Richard, Scotet, Emmanuel

“…V gamma 9V delta 2 T lymphocytes are the major human peripheral gamma delta T cell subset, with broad reactivity against stressed human cells, including tumor…”
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Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases by Nicholson, Richard, Murphy, Gillian, Breathnach, Richard

“…Rat transin and human stromelysin 2 mRNAs, which have been associated with malignant tumors, code for potential proteins with significant sequence homology to…”
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Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7 by Jakowlew, Sonia B., Breathnach, Richard, Jeltsch, Jean-Marc, Masiakowski, Piotr, Chambon, Pierre

“…We present the complete sequence of an mRNA which is induced by estrogen in the human breast cancer cell line MCF-7 [pS2 mRNA, Masiakowski et al., Nucleic…”
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The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V[gamma]9V[delta]2 T Cells by Sandstrom, Andrew, Peigné, Cassie-Marie, Léger, Alexandra, Crooks, James E, Konczak, Fabienne, Gesnel, Marie-Claude, Breathnach, Richard, Bonneville, Marc, Scotet, Emmanuel, Adams, Erin J

“…In humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, includingMycobacterium tuberculosis, through recognition of small pyrophosphate…”
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TIA-1 and TIAR Activate Splicing of Alternative Exons with Weak 5′ Splice Sites followed by a U-rich Stretch on Their Own Pre-mRNAs by Le Guiner, Caroline, Lejeune, Fabrice, Galiana, Delphine, Kister, Liliane, Breathnach, Richard, Stévenin, James, Del Gatto-Konczak, Fabienne

“…TIA-1 has recently been shown to activate splicing of specific pre-mRNAs transcribed from transiently transfected minigenes, and of some 5′ splice sites in…”
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Complex Interplay of Activating and Inhibitory Signals Received by Vγ9Vδ2 T Cells Revealed by Target Cell β2-Microglobulin Knockdown by Trichet, Valérie, Benezech, Cécile, Dousset, Christelle, Gesnel, Marie-Claude, Bonneville, Marc, Breathnach, Richard

“…Abstract Tumor cells often escape immunosurveillance by down-regulating MHC class I molecule expression. For human Vγ9Vδ2 T cells, a major peripheral blood T…”
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Combined Use of MS2 and PP7 Coat Fusions Shows that TIA-1 Dominates hnRNP A1 for K-SAM Exon Splicing Control by Gesnel, Marie-Claude, Breathnach, Richard, Del Gatto-Konczak, Fabienne

“…Splicing of the FGFR2 K-SAM exon is repressed by hnRNP A1 bound to the exon and activated by TIA-1 bound to the downstream intron. Both proteins are expressed…”
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Competition of PTB with TIA proteins for binding to a U-rich cis-element determines tissue-specific splicing of the myosin phosphatase targeting subunit 1 by Shukla, Supriya, Del Gatto-Konczak, Fabienne, Breathnach, Richard, Fisher, Steven A

“…A considerable amount of smooth muscle phenotypic diversity is generated by tissue-specific and developmentally regulated splicing of alternative exons. The…”
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