Search Results - "Riceputi, Laura"
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Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships
Published in Journal of medicinal chemistry (24-01-2013)“…Valosine containing protein (VCP), also known as p97, is a member of AAA ATPase family that is involved in several biological processes and plays a central…”
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Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors
Published in Bioorganic & medicinal chemistry (01-08-2014)“…[Display omitted] In the last decade the heat shock protein 90 (Hsp90) has emerged as a major therapeutic target and many efforts have been dedicated to the…”
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Henoch-Schönlein purpura and drug and vaccine use in childhood: a case-control study
Published in Italian journal of pediatrics (18-06-2016)“…Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood; nevertheless, its etiology and pathogenesis remain unknown despite the fact that a…”
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Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)
Published in Bioorganic & medicinal chemistry (15-11-2013)“…Fragment based approach and subsequent optimization of the fragment 1 led to the identification of the heat shock protein 90 (Hsp90) inhibitor 18 (NMS-E973),…”
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Vaccine effectiveness against severe laboratory-confirmed influenza in children: Results of two consecutive seasons in Italy
Published in Vaccine (31-07-2014)“…Highlights • Vaccine effectiveness in children visiting an Emergency Department for influenza. • Test negative case-control study in 11 paediatric centres in…”
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